Publications by authors named "Giles Hardingham"

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FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation.
Roza H A Masalmeh, John C Dawson, Virginia Alvarez Garcia, Morwenna T Muir, Roderick N Carter, Giles E Hardingham

Dis Model Mech· November 2025

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Maternal high fat and high sugar diet impacts on key DNA methylation enzymes in offspring brain in a sex-specific manner.
Kahyee Hor, Laura Dearden, Emily Herzstein, Susan Ozanne, Giles Hardingham

J Neuroendocrinol· August 2025

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Embracing the Modern Biochemistry of Brain Metabolism.
Juan P Bolaños, Cristina M Alberini, Angeles Almeida, L Felipe Barros, Gilles Bonvento, Giles E Hardingham

J Neurochem· July 2025

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Absence of GluN2A in hippocampal CA1 neurons leads to altered dendritic structure and reduced frequency of miniature excitatory synaptic events.
Farhana Yasmin, Katie F M Marwick, Daniel W Hunter, Sarfaraz Nawaz, Grant F Marshall, Giles E Hardingham

Brain Commun· March 2025

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Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus.
Mary O'Keeffe, Sam A Booker, Darren Walsh, Mosi Li, Chloe Henley, Giles E Hardingham

Nat Neurosci· February 2025

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Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.
Suvankar Pal, Jeremy Chataway, Robert Swingler, Malcolm R Macleod, Neil O Carragher, Giles Hardingham

Lancet Neurol· November 2024

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Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10 + 16 mutation.
Owen Dando, Robert McGeachan, Jamie McQueen, Paul Baxter, Nathan Rockley, Giles Hardingham

Neuropathol Appl Neurobiol· August 2024

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A comparison of basal and activity-dependent exon splicing in cortical-patterned neurons of human and mouse origin.
Owen Dando, Jamie McQueen, Karen Burr, Peter C Kind, Siddharthan Chandran, Giles E Hardingham

Front Mol Neurosci· August 2024

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Transfection in Primary Cultured Neuronal Cells.
Katie F M Marwick, Giles E Hardingham

Methods Mol Biol· July 2024

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Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder.
Laura Simões de Oliveira, Heather E O'Leary, Sarfaraz Nawaz, Rita Loureiro, Elizabeth C Davenport, Giles E Hardingham

Mol Autism· June 2024

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Synaptic gene expression changes in frontotemporal dementia due to the 10+16 mutation.
Owen Dando, Robert McGeachan, Jamie McQueen, Paul Baxter, Nathan Rockley, Giles Hardingham

medRxiv· April 2024

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Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.
Katharine E Askew, Joshua Beverley, Emma Sigfridsson, Stefan Szymkowiak, Katherine Emelianova, Giles E Hardingham

Glia· February 2024

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Laboratory Automated Interrogation of Data: an interactive web application for visualization of multilevel data from biological experiments.
Owen R Dando, Zrinko Kozic, Sam A Booker, Giles E Hardingham, Peter C Kind

Brain Commun· February 2024

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The consequences of neurodegenerative disease on neuron-astrocyte metabolic and redox interactions.
Zoeb Jiwaji, Giles E Hardingham

Neurobiol Dis· September 2023

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Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
Makis Tzioras, Michael J D Daniels, Caitlin Davies, Paul Baxter, Declan King, Giles E Hardingham

Cell Rep Med· September 2023

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General anesthesia alters CNS and astrocyte expression of activity-dependent and activity-independent genes.
Zoeb Jiwaji, Nóra M Márkus, Jamie McQueen, Katie Emelianova, Xin He, Giles E Hardingham

Front Netw Physiol· August 2023

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Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration.
Rickie Patani, Giles E Hardingham, Shane A Liddelow

Nat Rev Neurol· July 2023

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Differential splicing choices made by neurons and astrocytes and their importance when investigating signal-dependent alternative splicing in neural cells.
Paul S Baxter, Owen Dando, Giles E Hardingham

Front Mol Neurosci· July 2023

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Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration.
Irene Molina-Gonzalez, Rebecca K Holloway, Zoeb Jiwaji, Owen Dando, Sarah A Kent, Giles E Hardingham

Nat Commun· June 2023

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Long-term plasticity of astrocytic phenotypes and their control by neurons in health and disease.
Kyle S Wardlaw, Giles E Hardingham

Essays Biochem· March 2023

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Activation of Nrf2 to Optimise Immune Responses to Intracerebral Haemorrhage.
James J M Loan, Rustam Al-Shahi Salman, Barry W McColl, Giles E Hardingham

Biomolecules· October 2022

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NMDA Receptor C-Terminal Domain Signalling in Development, Maturity, and Disease.
Kirsty Haddow, Peter C Kind, Giles E Hardingham

Int J Mol Sci· September 2022

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Good, bad, and neglectful: Astrocyte changes in neurodegenerative disease.
Zoeb Jiwaji, Giles E Hardingham

Free Radic Biol Med· March 2022

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Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Zoeb Jiwaji, Sachin S Tiwari, Rolando X Avilés-Reyes, Monique Hooley, David Hampton, Giles E Hardingham

Nat Commun· January 2022

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Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model.
Samantha K Barton, Dario Magnani, Owen G James, Matthew R Livesey, Bhuvaneish T Selvaraj, Giles E Hardingham

Brain Commun· October 2021

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