Publications by authors named "Githa Elizabeth Mathew"

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3D-QSAR, Pharmacophore Modeling, ADMET and DFT Studies of Halogenated Conjugated Dienones as Potent MAO-B Inhibitors.
Githa Elizabeth Mathew, Chonny Herrera-Acevedo, Marcus Tullius Scotti, Sunil Kumar, Avni Berisha, Bijo Mathew

Curr Comput Aided Drug Des· April 2025

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Advancements in COVID-19 Testing: An In-depth Overview.
Rajesh Kumar, Seetha Harilal, Abdullah G Al-Sehemi, Mehboobali Pannipara, Githa Elizabeth Mathew, Bijo Mathew

Curr Pharm Biotechnol· June 2023

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Biological investigation of -methyl thiosemicarbazones as antimicrobial agents and bacterial carbonic anhydrases inhibitors.
Ilaria D'Agostino, Githa Elizabeth Mathew, Paola Angelini, Roberto Venanzoni, Giancarlo Angeles Flores, Bijo Mathew

J Enzyme Inhib Med Chem· December 2022

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Replacement of Chalcone-Ethers with Chalcone-Thioethers as Potent and Highly Selective Monoamine Oxidase-B Inhibitors and Their Protein-Ligand Interactions.
Bijo Mathew, Jong Min Oh, Ahmed Khames, Mohamed A Abdelgawad, T M Rangarajan, Githa Elizabeth Mathew

Pharmaceuticals (Basel)· November 2021

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Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson's disease.
Githa Elizabeth Mathew, Jong Min Oh, Kumar Mohan, Anandkumar Tengli, Bijo Mathew

J Biomol Struct Dyn· August 2021

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The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic.
Rajesh Kumar, Seetha Harilal, Abdullah G Al-Sehemi, Githa Elizabeth Mathew, Simone Carradori, Bijo Mathew

Curr Med Chem· June 2021

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Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.
Bijo Mathew, Della Grace Thomas Parambi, Vishnu Sankar Sivasankarapillai, Md Sahab Uddin, Jerad Suresh, Githa Elizabeth Mathew

CNS Neurol Disord Drug Targets· September 2020

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Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules.
Seetha Harilal, Jobin Jose, Della Grace Thomas Parambi, Rajesh Kumar, Mazhuvancherry Kesavan Unnikrishnan, Githa Elizabeth Mathew, Bijo Mathew

Brain Res Bull· July 2020

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Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.
Jobin Jose, Rajesh Kumar, Seetha Harilal, Githa Elizabeth Mathew, Della Grace Thomas Parambi, Bijo Mathew

Environ Sci Pollut Res Int· June 2020

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Advancements in nanotherapeutics for Alzheimer's disease: current perspectives.
Seetha Harilal, Jobin Jose, Della Grace Thomas Parambi, Rajesh Kumar, Githa Elizabeth Mathew, Bijo Mathew

J Pharm Pharmacol· September 2019

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Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.
Bijo Mathew, Seung Cheol Baek, Della Grace Thomas Parambi, Jae Pil Lee, Monu Joy, Githa Elizabeth Mathew

Medchemcomm· November 2018

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Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.
Bijo Mathew, Githa Elizabeth Mathew, Jacobus P Petzer, Anel Petzer

Comb Chem High Throughput Screen· November 2017

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Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.
Bijo Mathew, Githa Elizabeth Mathew, Gulberk Ucar, Monu Joy, E K Nafna

Int J Biol Macromol· November 2017

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Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.
Bijo Mathew, Adebayo A Adeniyi, Sanal Dev, Monu Joy, Gülberk Ucar, Githa Elizabeth Mathew

J Phys Chem B· February 2017

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Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.
Bijo Mathew, Gülberk Uçar, Githa Elizabeth Mathew, Sincy Mathew, Praseedha Kalatharakkal Purapurath

ChemMedChem· December 2016

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Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.
Bijo Mathew, Abitha Haridas, Gülberk Uçar, Ipek Baysal, Adebayo A Adeniyi, Githa Elizabeth Mathew

Int J Biol Macromol· October 2016

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Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.
Bijo Mathew, Githa Elizabeth Mathew, Gülberk Uçar, Ipek Baysal, Jerad Suresh, Sincy Mathew

Chem Biodivers· August 2016

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Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.
Bijo Mathew, Githa Elizabeth Mathew, Jerad Suresh, Dhasthakeer Usman, Puthucode Natarajan Shiva Subramanyan

Cent Nerv Syst Agents Med Chem· January 2016

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Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.
Bijo Mathew, Githa Elizabeth Mathew, Gülberk Uçar, Ipek Baysal, Jerad Suresh

Bioorg Chem· October 2015

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Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.
Githa Elizabeth Mathew, Bijo Mathew, S Gokul, Rahul Krishna, M P Farisa

Anc Sci Life· June 2015

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Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.
Bijo Mathew, Jerad Suresh, Sockalingam Anbazhagan, Githa Elizabeth Mathew

Cent Nerv Syst Agents Med Chem· December 2014

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