Publications by authors named "Giulia Bononi"

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ProSECFPs: A Novel Fingerprint-Based Protein Representation Method for Missense Mutation Pathogenicity Prediction.
Clarissa Poles, Miriana Di Stefano, Lisa Piazza, Giulia Bononi, Giulio Poli

J Chem Inf Model· December 2025

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ADvisor: An Open-Source Tool for Applicability Domain Definition and Optimization in Molecular Predictive Modeling.
Lisa Piazza, Clarissa Poles, Giulia Bononi, Carlotta Granchi, Miriana Di Stefano

J Chem Inf Model· November 2025

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Methods for Assessing MAGL Enzymatic Activity: An Extensive Review of Past and Emerging Approaches.
Giulia Bononi, Eva Landucci, Miriana Di Stefano, Lisa Piazza, Simone Bertini

Int J Mol Sci· October 2025

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Discovery of reversible monoacylglycerol lipase (MAGL) inhibitors based on ortho-hydroxyanilide scaffold.
Giulia Bononi, Francesca Gado, Samuele Masoni, Diana Scalabrini, Larissa Della Vedova

Bioorg Chem· August 2025

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A Machine Learning Platform for Isoform-Specific Identification and Profiling of Human Carbonic Anhydrase Inhibitors.
Lisa Piazza, Miriana Di Stefano, Clarissa Poles, Giulia Bononi, Giulio Poli

Pharmaceuticals (Basel)· July 2025

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Identification of a Possible Endocannabinoid-Mediated Mechanism of Action of Cetylated Fatty Acids.
Giulia Bononi, Carlotta Granchi, Tiziano Tuccinardi, Filippo Minutolo

Biomolecules· March 2025

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A patent review of lactate dehydrogenase inhibitors (2014-present).
Giulia Bononi, Valeria Di Bussolo, Tiziano Tuccinardi, Filippo Minutolo, Carlotta Granchi

Expert Opin Ther Pat· November 2024

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The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review.
Giulia Bononi, Chiara Lonzi, Tiziano Tuccinardi, Filippo Minutolo, Carlotta Granchi

Molecules· April 2024

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Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors.
Miriana Di Stefano, Samuele Masoni, Giulia Bononi, Giulio Poli, Salvatore Galati

Eur J Med Chem· January 2024

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Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying cardioprotective activities.
Giulia Bononi, Valentina Citi, Alma Martelli, Giulio Poli, Tiziano Tuccinardi

RSC Med Chem· January 2024

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Historical perspective of tumor glycolysis: A century with Otto Warburg.
Giulia Bononi, Samuele Masoni, Valeria Di Bussolo, Tiziano Tuccinardi, Carlotta Granchi

Semin Cancer Biol· November 2022

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Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives.
Giulia Bononi, Valentina Citi, Margherita Lapillo, Alma Martelli, Giulio Poli

Molecules· October 2022

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Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors.
Miriana Di Stefano, Salvatore Galati, Gabriella Ortore, Isabella Caligiuri, Flavio Rizzolio, Giulia Bononi

Int J Mol Sci· September 2022

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Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives.
Giulia Bononi, Miriana Di Stefano, Giulio Poli, Gabriella Ortore, Philip Meier

J Med Chem· May 2022

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New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds.
Giulia Bononi, Lorenzo Flori, Valentina Citi, Cecilia Acciai, Viviana Nocilla

Pharmaceuticals (Basel)· March 2022

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Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold.
Giulia Bononi, Giacomo Tonarini, Giulio Poli, Ivana Barravecchia, Isabella Caligiuri

Eur J Med Chem· November 2021

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α/β-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases.
Giulia Bononi, Tiziano Tuccinardi, Flavio Rizzolio, Carlotta Granchi

J Med Chem· July 2021

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An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present).
Giulia Bononi, Giulio Poli, Flavio Rizzolio, Tiziano Tuccinardi, Marco Macchia

Expert Opin Ther Pat· February 2021

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Glycoconjugated Metal Complexes as Cancer Diagnostic and Therapeutic Agents.
Giulia Bononi, Dalila Iacopini, Gaspare Cicio, Sebastiano Di Pietro, Carlotta Granchi

ChemMedChem· January 2021

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Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.
Carlotta Granchi, Giulia Bononi, Rebecca Ferrisi, Eleonora Gori, Giulia Mantini

Eur J Med Chem· January 2021

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The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies.
Btissame El Hassouni, Carlotta Granchi, Andrea Vallés-Martí, I Gede Putu Supadmanaba, Giulia Bononi

Semin Cancer Biol· February 2020

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Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor.
Carlotta Granchi, Margherita Lapillo, Sandra Glasmacher, Giulia Bononi, Cristina Licari

J Med Chem· February 2019

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An Update on Patents Covering Agents That Interfere with the Cancer Glycolytic Cascade.
Serena Fortunato, Giulia Bononi, Carlotta Granchi, Filippo Minutolo

ChemMedChem· November 2018

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Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors.
Giulia Bononi, Carlotta Granchi, Margherita Lapillo, Massimiliano Giannotti, Daniela Nieri

Eur J Med Chem· September 2018

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New Phenylethanoid Glycosides from Cistanche phelypaea and Their Activity as Inhibitors of Monoacylglycerol Lipase (MAGL).
Khadidja Aya Beladjila, Djemaa Berrehal, Nunziatina De Tommasi, Carlotta Granchi, Giulia Bononi

Planta Med· July 2018

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