Publications by authors named "Giulia Candini"

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Safety and efficacy of Igk-TATk-CDKL5 gene therapy in mosaic CDKL5 deficiency.
Giorgio Medici, Marianna Tassinari, Manuela Loi, Angelica Marina Bove, Beatrice Casadei Garofani, Giulia Candini

Neurotherapeutics· October 2025

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Lactic acid bacteria as microbial cell factories for the in vivo delivery of therapeutic proteins as secretable TAT fusion products.
Giorgio Medici, Giulia Candini, Nicola Mottolese, Beatrice Uguagliati, Federica Trebbi

J Biol Eng· July 2025

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Adult-Onset Deletion of CDKL5 in Forebrain Glutamatergic Neurons Impairs Synaptic Integrity and Behavior in Mice.
Nicola Mottolese, Feliciana Iannibelli, Giulia Candini, Federica Trebbi, Manuela Loi

Int J Mol Sci· July 2025

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Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder.
Manuela Loi, Francesca Valenti, Giorgio Medici, Nicola Mottolese, Giulia Candini

Int J Mol Sci· February 2025

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Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder.
Nicola Mottolese, Manuela Loi, Stefania Trazzi, Marianna Tassinari, Beatrice Uguagliati, Giulia Candini

J Neurodev Disord· November 2024

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Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder.
Nicola Mottolese, Beatrice Uguagliati, Marianna Tassinari, Camilla Bruna Cerchier, Manuela Loi, Giulia Candini

Biomolecules· September 2023

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Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder.
Marianna Tassinari, Beatrice Uguagliati, Stefania Trazzi, Camilla Bruna Cerchier, Ottavia Vera Cavina, Giulia Candini

Neurobiol Dis· June 2023

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Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder.
Manuela Loi, Stefano Bastianini, Giulia Candini, Nicola Rizzardi, Giorgio Medici

Int J Mol Sci· March 2023

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Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder.
Giorgio Medici, Marianna Tassinari, Giuseppe Galvani, Stefano Bastianini, Laura Gennaccaro, Giulia Candini

Neurotherapeutics· October 2022

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Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder.
Marianna Tassinari, Nicola Mottolese, Giuseppe Galvani, Domenico Ferrara, Laura Gennaccaro, Giulia Candini

Int J Mol Sci· August 2022

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