Publications by authors named "Giuseppa Pennetta"

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Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy.
Anzer Khan, Simona Paro, Leeanne McGurk, Nagraj Sambrani, Marion C Hogg, Giuseppa Pennetta

BMC Biol· February 2020

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Emerging Links between Lipid Droplets and Motor Neuron Diseases.
Giuseppa Pennetta, Michael A Welte

Dev Cell· May 2018

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Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture.
Laura C Graham, Samantha L Eaton, Paula J Brunton, Abdelmadjid Atrih, Colin Smith, Giuseppa Pennetta

Mol Neurodegener· October 2017

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Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo.
Maica Llavero Hurtado, Heidi R Fuller, Andrew M S Wong, Samantha L Eaton, Thomas H Gillingwater, Giuseppa Pennetta

Sci Rep· September 2017

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Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.
Rachel A Kline, Kevin A Kaifer, Erkan Y Osman, Francesco Carella, Ariana Tiberi, Giuseppa Pennetta

PLoS Genet· March 2017

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Sideroflexin 3 is an α-synuclein-dependent mitochondrial protein that regulates synaptic morphology.
Inês S Amorim, Laura C Graham, Roderick N Carter, Nicholas M Morton, Fella Hammachi, Giuseppa Pennetta

J Cell Sci· January 2017

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Insights into ALS pathomechanisms: from flies to humans.
Andrea Chai, Giuseppa Pennetta

Fly (Austin)· October 2016

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Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense.
Otto Morris, Xi Liu, Celia Domingues, Christopher Runchel, Andrea Chai, Giuseppa Pennetta

Cell Host Microbe· September 2016

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Why Quantification Matters: Characterization of Phenotypes at the Drosophila Larval Neuromuscular Junction.
Mario Sanhueza, Anisha Kubasik-Thayil, Giuseppa Pennetta

J Vis Exp· May 2016

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Network analyses reveal novel aspects of ALS pathogenesis.
Mario Sanhueza, Andrea Chai, Colin Smith, Brett A McCray, T Ian Simpson, Giuseppa Pennetta

PLoS Genet· March 2015

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Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles.
Mario Sanhueza, Luigi Zechini, Trudy Gillespie, Giuseppa Pennetta

Biol Open· January 2014

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Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis.
Stuart Forrest, Andrea Chai, Mario Sanhueza, Manuela Marescotti, Katherine Parry, Giuseppa Pennetta

Hum Mol Genet· July 2013

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Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis.
Han-Jou Chen, Georgia Anagnostou, Andrea Chai, James Withers, Alex Morris, Giuseppa Pennetta

J Biol Chem· December 2010

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hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction.
Andrea Chai, James Withers, Young Ho Koh, Katherine Parry, Hong Bao, Giuseppa Pennetta

Hum Mol Genet· January 2008

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Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner.
Giuseppa Pennetta, Peter Robin Hiesinger, Ruth Fabian-Fine, Ian A Meinertzhagen, Hugo J Bellen

Neuron· July 2002

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Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila.
Thomas E Lloyd, Richard Atkinson, Mark N Wu, Yi Zhou, Giuseppa Pennetta

Cell· January 2002

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