Publications by authors named "Giuseppina Comito"

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ESR1 Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer.
Francesca Bonechi, Marina Bacci, Nicla Lorito, Alfredo Smiriglia, Angela Subbiani, Giuseppina Comito

Cancer Res· November 2025

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GPR55 senses lactate to sustain motility in prostate cancer cells.
Giovanna Sgrignani, Marta Iozzo, Lara Di Leonardo, Elisa Pardella, Erica Pranzini, Giuseppina Comito

Mol Cell Biochem· September 2025

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Targeting carbonic anhydrase IX/XII prevents the anti-ferroptotic effect of stromal lactic acid in prostate carcinoma.
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo

Mol Oncol· September 2025

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Sex-related changes in lactate dehydrogenase A expression differently impact the immune response in melanoma.
Marta Iozzo, Giuseppina Comito, Luigi Ippolito, Giada Sandrini, Elisa Pardella

FEBS J· June 2025

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Setup of an In Vitro Three-Dimensional Stromalized Prostate Cancer Model Using Gelatin Microparticles.
Giulia Gangarossa, Marta Iozzo, Giulia Mugnaini, Rita Gelli, Luigi Ippolito, Giuseppina Comito

ACS Omega· June 2025

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Piezo1, F-Actin Remodeling, and Podocyte Survival and Regeneration.
Maria Elena Melica, Giulia Antonelli, Roberto Semeraro, Gilda La Regina, Tommaso Dafichi, Giuseppina Comito

J Am Soc Nephrol· April 2025

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Ganglioside GD2 Contributes to a Stem-Like Phenotype in Intrahepatic Cholangiocarcinoma.
Antonella Mannini, Mirella Pastore, Alessia Giachi, Margherita Correnti, Elena Spínola Lasso, Giuseppina Comito

Liver Int· January 2025

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Estrogen-dependent activation of TRX2 reverses oxidative stress and metabolic dysfunction associated with steatotic disease.
Alfredo Smiriglia, Nicla Lorito, Marina Bacci, Angela Subbiani, Francesca Bonechi, Giuseppina Comito

Cell Death Dis· January 2025

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Limiting serine availability during tumor progression promotes muscle wasting in cancer cachexia.
Erica Pranzini, Livio Muccillo, Ilaria Nesi, Alice Santi, Caterina Mancini, Giuseppina Comito

Cell Death Discov· December 2024

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Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer.
Luigi Ippolito, Assia Duatti, Marta Iozzo, Giuseppina Comito, Elisa Pardella

EMBO Rep· August 2024

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FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.
Nicla Lorito, Angela Subbiani, Alfredo Smiriglia, Marina Bacci, Francesca Bonechi, Giuseppina Comito

EMBO Mol Med· July 2024

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Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER breast cancer.
Marina Bacci, Nicla Lorito, Alfredo Smiriglia, Angela Subbiani, Francesca Bonechi, Giuseppina Comito

Sci Transl Med· February 2024

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Editorial: Tumor microenvironment, inflammation, and resistance to immunotherapies.
Julie Decock, Giuseppina Comito, Apostolos Zaravinos

Front Oncol· May 2023

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Lactate Rewires Lipid Metabolism and Sustains a Metabolic-Epigenetic Axis in Prostate Cancer.
Luigi Ippolito, Giuseppina Comito, Matteo Parri, Marta Iozzo, Assia Duatti

Cancer Res· April 2022

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Endocannabinoid System and Tumour Microenvironment: New Intertwined Connections for Anticancer Approaches.
Marta Iozzo, Giovanna Sgrignani, Giuseppina Comito, Paola Chiarugi, Elisa Giannoni

Cells· December 2021

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Zoledronic Acid Inhibits the RhoA-mediated Amoeboid Motility of Prostate Cancer Cells.
Laura Pietrovito, Giuseppina Comito, Matteo Parri, Elisa Giannoni, Paola Chiarugi

Curr Cancer Drug Targets· September 2020

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Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repression.
Antonio Pezone, Maria Letizia Taddei, Alfonso Tramontano, Jacopo Dolcini, Francesca Ludovica Boffo, Giuseppina Comito

Nucleic Acids Res· September 2020

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Glucose Metabolic Reprogramming of ER Breast Cancer in Acquired Resistance to the CDK4/6 Inhibitor Palbociclib.
Nicla Lorito, Marina Bacci, Alfredo Smiriglia, Michele Mannelli, Matteo Parri, Giuseppina Comito

Cells· March 2020

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Nutritional Exchanges Within Tumor Microenvironment: Impact for Cancer Aggressiveness.
Giuseppina Comito, Luigi Ippolito, Paola Chiarugi, Paolo Cirri

Front Oncol· March 2020

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Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer.
Luigi Ippolito, Andrea Morandi, Maria Letizia Taddei, Matteo Parri, Giuseppina Comito

Oncogene· July 2019

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Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer.
Marina Bacci, Nicla Lorito, Luigi Ippolito, Matteo Ramazzotti, Simone Luti, Giuseppina Comito

Cell Rep· July 2019

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Stromal-induced downregulation of miR-1247 promotes prostate cancer malignancy.
Maria Letizia Taddei, Lorenzo Cavallini, Matteo Ramazzotti, Giuseppina Comito, Laura Pietrovito

J Cell Physiol· June 2019

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Conjugation of a GM3 lactone mimetic on carbon nanotubes enhances the related inhibition of melanoma-associated metastatic events.
Paolo Arosio, Giuseppina Comito, Francesco Orsini, Alessandro Lascialfari, Paola Chiarugi

Org Biomol Chem· August 2018

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Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).
Marco Fragai, Giuseppina Comito, Lorenzo Di Cesare Mannelli, Roberta Gualdani, Vito Calderone

J Med Chem· November 2017

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Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1.
Pedro Barcellos-de-Souza, Giuseppina Comito, Coral Pons-Segura, Maria Letizia Taddei, Valentina Gori

Stem Cells· October 2016

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