Publications by authors named "Gopal Dhar"

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Design, Synthesis, and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408.
Denise C Grünenfelder, Upender Velaparthi, Jayakumar S Warrier, Louis Chupak, Chetan Padmakar Darne, T G Murali Dhar, Gopal Dhar

J Med Chem· October 2025

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Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.
Emily C Cherney, Liping Zhang, Weiwei Guo, Audris Huang, David Williams, Gopal Dhar

ACS Med Chem Lett· July 2021

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Discovery of Imidazopyridines as Potent Inhibitors of Indoleamine 2,3-Dioxygenase 1 for Cancer Immunotherapy.
Liping Zhang, Emily C Cherney, Xiao Zhu, Tai-An Lin, Johnni Gullo-Brown, Gopal Dhar

ACS Med Chem Lett· March 2021

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Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent.
Upender Velaparthi, Chetan Padmakar Darne, Jayakumar Warrier, Peiying Liu, Hasibur Rahaman, Gopal Dhar

ACS Med Chem Lett· February 2020

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The MAZ transcription factor is a downstream target of the oncoprotein Cyr61/CCN1 and promotes pancreatic cancer cell invasion via CRAF-ERK signaling.
Gargi Maity, Inamul Haque, Arnab Ghosh, Gopal Dhar, Vijayalaxmi Gupta, Abhishek Choudhary

J Biol Chem· March 2018

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Deficiency of CCN5/WISP-2-Driven Program in breast cancer Promotes Cancer Epithelial cells to mesenchymal stem cells and Breast Cancer growth.
Amlan Das, Kakali Dhar, Gargi Maity, Sandipto Sarkar, Arnab Ghosh, Gopal Dhar

Sci Rep· April 2017

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Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1.
Kakali Dhar, Gopal Dhar, Monami Majumder, Inamul Haque, Smita Mehta

Mol Cancer· August 2010

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2-methoxyestradiol inhibits Barrett's esophageal adenocarcinoma growth and differentiation through differential regulation of the beta-catenin-E-cadherin axis.
Suman Kambhampati, Snigdha Banerjee, Kakali Dhar, Smita Mehta, Inamul Haque, Gopal Dhar

Mol Cancer Ther· March 2010

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Crocetin inhibits pancreatic cancer cell proliferation and tumor progression in a xenograft mouse model.
Animesh Dhar, Smita Mehta, Gopal Dhar, Kakali Dhar, Snigdha Banerjee

Mol Cancer Ther· February 2009

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CCN5/WISP-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells.
Snigdha Banerjee, Gopal Dhar, Inamul Haque, Suman Kambhampati, Smita Mehta

Cancer Res· September 2008

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Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2.
Gopal Dhar, Snigdha Banerjee, Kakali Dhar, Ossama Tawfik, Matthew S Mayo

Cancer Res· June 2008

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2-Methoxyestradiol modulates beta-catenin in prostate cancer cells: a possible mediator of 2-methoxyestradiol-induced inhibition of cell growth.
Peter J Van Veldhuizen, Gibanananda Ray, Snigdha Banerjee, Gopal Dhar, Suman Kambhampati, Animesh Dhar

Int J Cancer· February 2008

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Loss of WISP-2/CCN5 signaling in human pancreatic cancer: a potential mechanism for epithelial-mesenchymal-transition.
Gopal Dhar, Smita Mehta, Snigdha Banerjee, Ashleigh Gardner, Bryan M McCarty

Cancer Lett· August 2007

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Insulin-like growth factor-1 (IGF-1) induces WISP-2/CCN5 via multiple molecular cross-talks and is essential for mitogenic switch by IGF-1 axis in estrogen receptor-positive breast tumor cells.
Kakali Dhar, Snigdha Banerjee, Gopal Dhar, Krishanu Sengupta, Sushanta K Banerjee

Cancer Res· February 2007

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Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1.
Snigdha Banerjee, Krishanu Sengupta, Kakali Dhar, Smita Mehta, Patricia A D'Amore, Gopal Dhar

Mol Carcinog· November 2006

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Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways.
Gibanananda Ray, Gopal Dhar, Peter J Van Veldhuizen, Snigdha Banerjee, Neela K Saxena

Biochemistry· March 2006

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Molecular basis of protective effect by crocetin on survival and liver tissue damage following hemorrhagic shock.
Animesh Dhar, George Cherian, Gopal Dhar, Gibanananda Ray, Ram Sharma

Mol Cell Biochem· October 2005

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Epidermal growth factor receptor: is a novel therapeutic target for pancreatic cancer?
Animesh Dhar, Smita Mehta, Snigdha Banerjee, Kakali Dhar, Gopal Dhar

Front Biosci· May 2005

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Influence of the organophosphorus insecticide phosphamidon on lentic water.
Gopal Dhar, Sudip Barat, Kakali Mitra Dhar

J Environ Biol· July 2004

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