Publications by authors named "Gordon Bolger"

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Relationship between the in vitro efficacy, pharmacokinetics and in vivo efficacy of curcumin.
Gordon T Bolger, Kresimir Pucaj, Yvonne O Minta, Peter Sordillo

Biochem Pharmacol· November 2022

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Ketotifen is a Prodrug. Norketotifen is the active metabolite.
Axel Karl Gunnar Aberg, Nada Arulnesan, Gordon T Bolger, Vincent B Ciofalo, Kresimir Pucaj

Drug Dev Res· April 2022

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Towards an exposure narrative for metals and arsenic in historically contaminated Ni refinery soils: Relationships between speciation, bioavailability, and bioaccessibility.
Michael D Dutton, Luba Vasiluk, Frederick Ford, Maria Bellantino Perco, Simon R Taylor, Gordon T Bolger

Sci Total Environ· October 2019

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Intense Uptake of Liposomal Curcumin by Multiple Myeloma Cell Lines: Comparison to Normal Lymphocytes, Red Blood Cells and Chronic Lymphocytic Leukemia Cells.
Gordon T Bolger, Albert Licollari, Richard Bagshaw, Aimin Tan, Richard Greil

Anticancer Res· March 2019

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Pharmacokinetics of liposomal curcumin (Lipocurc™) infusion: effect of co-medication in cancer patients and comparison with healthy individuals.
Gordon T Bolger, Albert Licollari, Amin Tan, Richard Greil, Brigitta Vcelar

Cancer Chemother Pharmacol· February 2019

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A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc) in patients with locally advanced or metastatic cancer.
Richard Greil, Sigrun Greil-Ressler, Lukas Weiss, Charlotte Schönlieb, Teresa Magnes, Gordon T Bolger

Cancer Chemother Pharmacol· October 2018

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Improving the selectivity and sensitivity for quantifying 8-α-hydroxy-mutilin in rabbit tissues by using basic mobile phases and negative ionization.
Aimin Tan, Guifen Gu, Xuan Gui, Yanxin Wu, Gordon Bolger

J Chromatogr B Analyt Technol Biomed Life Sci· January 2018

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Distribution of Curcumin and THC in Peripheral Blood Mononuclear Cells Isolated from Healthy Individuals and Patients with Chronic Lymphocytic Leukemia.
Gordon T Bolger, Albert Licollari, Aimin Tan, Richard Greil, Lisa Pleyer

Anticancer Res· January 2018

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Distribution and Metabolism of Lipocurc™ (Liposomal Curcumin) in Dog and Human Blood Cells: Species Selectivity and Pharmacokinetic Relevance.
Gordon T Bolger, Albert Licollari, Aimin Tan, Richard Greil, Brigitta Vcelar

Anticancer Res· July 2017

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Safety and Biosimilarity of iorLeukoCIM Compared to Neupogen Based on Toxicity, Pharmacodynamic, and Pharmacokinetic Studies in the Sprague-Dawley Rat.
Albert Licollari, Katherine Riddle, Simon R Taylor, Nuris Ledon, Gordon T Bolger

J Pharm Sci· June 2017

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Use of basic mobile phase to improve chromatography and boost sensitivity for quantifying tetrahydrocurcumin in human plasma by LC-MS/MS.
Aimin Tan, Yanxin Wu, Molly Wong, Albert Licollari, Gordon Bolger

J Chromatogr B Analyt Technol Biomed Life Sci· August 2016

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From B.Sc. to Ph.D., my shuffle off to Buffalo.
Gordon T Bolger

Biochem Pharmacol· November 2015

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Characterization and Validation of a Canine Pruritic Model.
Gunnar A K Aberg, Nada Arulnesan, Gordon T Bolger, Vincent B Ciofalo, Kresimir Pucaj

Drug Dev Res· August 2015

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Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite.
Pierre L Beaulieu, Gordon Bolger, Martin Duplessis, Alexandre Gagnon, Michel Garneau

Bioorg Med Chem Lett· March 2015

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Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity.
Pierre L Beaulieu, Gordon Bolger, Dan Deon, Martin Duplessis, Gulrez Fazal

Bioorg Med Chem Lett· March 2015

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Safety, tolerability and pharmacokinetics of liposomal curcumin in healthy humans.
Angela Storka, Brigitta Vcelar, Uros Klickovic, Ghazaleh Gouya, Stefan Weisshaar, Gordon Bolger

Int J Clin Pharmacol Ther· January 2015

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Safety and biosimilarity of ior(®) EPOCIM compared with Eprex(®) based on toxicologic, pharmacodynamic, and pharmacokinetic studies in the Sprague-Dawley rat.
Kresimir Pucaj, Katherine Riddle, Simon R Taylor, Nuris Ledon, Gordon T Bolger

J Pharm Sci· November 2014

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Monitoring drug self-aggregation and potential for promiscuity in off-target in vitro pharmacology screens by a practical NMR strategy.
Steven R LaPlante, Norman Aubry, Gordon Bolger, Pierre Bonneau, Rebekah Carson

J Med Chem· September 2013

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Safety and pharmacokinetic studies of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol or γ-tocopherol in beagle dogs.
Misagh Alipour, Panagiotis Mitsopoulos, Milton G Smith, Gordon Bolger, Kresimir Pucaj

Toxicol Mech Methods· July 2013

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The liver partition coefficient-corrected inhibitory quotient and the pharmacokinetic-pharmacodynamic relationship of directly acting anti-hepatitis C virus agents in humans.
Jianmin Duan, Gordon Bolger, Michel Garneau, Ma'an Amad, Joëlle Batonga

Antimicrob Agents Chemother· October 2012

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Tissue distribution of (Lipocurc™) liposomal curcumin and tetrahydrocurcumin following two- and eight-hour infusions in Beagle dogs.
Dharmendr Matabudul, Kresimir Pucaj, Gordon Bolger, Brigitta Vcelar, Muhammed Majeed

Anticancer Res· October 2012

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Infusion pharmacokinetics of Lipocurc™ (liposomal curcumin) and its metabolite tetrahydrocurcumin in Beagle dogs.
Lawrence Helson, Gordon Bolger, Muhammed Majeed, Brigitta Vcelar, Kresimir Pucaj

Anticancer Res· October 2012

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Cross-species absorption, metabolism, distribution and pharmacokinetics of BI 201335, a potent HCV genotype 1 NS3/4A protease inhibitor.
Jianmin Duan, Chan-Loi Yong, Michel Garneau, Ma'an Amad, Gordon Bolger

Xenobiotica· February 2012

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Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease.
Peter W White, Montse Llinàs-Brunet, Ma'an Amad, Richard C Bethell, Gordon Bolger

Antimicrob Agents Chemother· November 2010

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Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase.
Michel Liuzzi, Stephen W Mason, Mireille Cartier, Carol Lawetz, Robert S McCollum, Gordon Bolger

J Virol· October 2005

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