Publications by authors named "Gordon Otto"

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Tepotinib in patients with non-small cell lung cancer with high-level MET amplification detected by liquid biopsy: VISION Cohort B.
Xiuning Le, Luis G Paz-Ares, Jan Van Meerbeeck, Santiago Viteri, Carlos Cabrera Galvez, Gordon Otto

Cell Rep Med· November 2023

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Tepotinib Treatment in Patients With MET Exon 14-Skipping Non-Small Cell Lung Cancer: Long-term Follow-up of the VISION Phase 2 Nonrandomized Clinical Trial.
Julien Mazieres, Paul K Paik, Marina C Garassino, Xiuning Le, Hiroshi Sakai, Gordon Otto

JAMA Oncol· September 2023

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Safety of Tepotinib in Patients With MET Exon 14 Skipping NSCLC and Recommendations for Management.
Remi Veillon, Hiroshi Sakai, Xiuning Le, Enriqueta Felip, Alexis B Cortot, Gordon Otto

Clin Lung Cancer· June 2022

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Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice.
Xiuning Le, Hiroshi Sakai, Enriqueta Felip, Remi Veillon, Marina Chiara Garassino, Gordon Otto

Clin Cancer Res· March 2022

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A large multicentre, randomized, double-blind, cross-over study in healthy volunteers to compare pharmacokinetics, pharmacodynamics and safety of a pegfilgrastim biosimilar with its US- and EU-reference biologics.
Anne Bellon, Jessie Wang, Andrej Skerjanec, Maria Velinova, Daniel Dickerson, Gordon P Otto

Br J Clin Pharmacol· June 2020

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Safety analysis of proposed pegfilgrastim biosimilar in Phase I and Phase III studies.
Nadia Harbeck, Jessie Wang, Gordon Philipp Otto, Sreekanth Gattu, Andriy Krendyukov

Future Oncol· April 2019

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Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching.
James Trauer, Stephen Muhi, Emma S McBryde, Shmeylan A Al Harbi, Yaseen M Arabi, Gordon P Otto

Crit Care Med· November 2017

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Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).
Gordon P Otto, Birgit Rathkolb, Manuela A Oestereicher, Christoph J Lengger, Corinna Moerth

J Am Assoc Lab Anim Sci· February 2017

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Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis.
Ha-Yeun Chung, Daniel C Hupe, Gordon P Otto, Marcel Sprenger, Alexander C Bunck

Mol Med· September 2016

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Plasma Neutrophil Gelatinase-Associated Lipocalin Is Primarily Related to Inflammation during Sepsis: A Translational Approach.
Gordon P Otto, Jorge Hurtado-Oliveros, Ha-Yeun Chung, Kristin Knoll, Thomas Neumann

PLoS One· February 2016

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Impact of antibiotic treatment intensity on long-term sepsis-associated kidney injury in a polymicrobial peritoneal contamination and infection model.
Gordon P Otto, Benedikt Grünwald, Christian Geis, Susanne Köthe, Jorge Hurtado-Oliveros

Nephron· December 2015

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Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation.
Michael Liembo Ekaney, Gordon Philipp Otto, Maik Sossdorf, Christoph Sponholz, Michael Boehringer

Crit Care· September 2014

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Renal outcome after vancomycin treatment and renal replacement therapy in patients with severe sepsis and septic shock: a retrospective study.
Gordon P Otto, Maik Sossdorf, Hannes Breuel, Peter Schlattmann, Ole Bayer

J Crit Care· August 2014

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Criticizing reporting standards fails to improve quality in animal research.
Gordon P Otto, Ralf A Claus

Crit Care· March 2014

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Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock.
Gordon Philipp Otto, Maik Sossdorf, Janina Boettel, Björn Kabisch, Hannes Breuel

Platelets· February 2014

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Potential effect of physiotherapeutic treatment on mortality rate in patients with severe sepsis and septic shock: a retrospective cohort analysis.
Maik Sossdorf, Gordon P Otto, Katja Menge, Ralf A Claus, Wolfgang Lösche

J Crit Care· December 2013

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Physical exercise induces specific adaptations resulting in reduced organ injury and mortality during severe polymicrobial sepsis.
Maik Sossdorf, Jacqueline Fischer, Stefan Meyer, Katja Dahlke, Bianka Wissuwa, Gordon P Otto

Crit Care Med· October 2013

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Novel approach for bacteremia detection in patients with end-stage renal failure undergoing hemodialysis.
Gordon P Otto, Madlen Kropf, Jürgen Rödel, Wolfgang Lösche, Christiane Rüster

Int J Artif Organs· October 2013

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Limitation of (1→3)-β-D-glucan monitoring in major elective surgery involving cardiopulmonary bypass.
Gordon P Otto, Katrin Ludewig, Ilse D Jacobsen, Barbara Schaarschmidt, Bernhard Hube

Crit Care· June 2013

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Impact of sepsis-associated cytokine storm on plasma NGAL during acute kidney injury in a model of polymicrobial sepsis.
Gordon P Otto, Martin Busch, Maik Sossdorf, Ralf A Claus

Crit Care· March 2013

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Benefit of low-dose aspirin and non-steroidal anti-inflammatory drugs in septic patients.
Maik Sossdorf, Gordon P Otto, Janina Boettel, Johannes Winning, Wolfgang Lösche

Crit Care· January 2013

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Arginine metabolism is markedly impaired in polymicrobial infected mice.
Gordon P Otto, Sophie Neugebauer, Ralf A Claus, Maik Sossdorf

Crit Care· December 2012

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A method for detection and quantification of hydroxyethyl starch in plasma.
Gordon P Otto, Bianka Wissuwa, Anne Mehnert, Sascha Marx, Michael Raessler

Crit Care· May 2012

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Persistent Chlamydia trachomatis infection of HeLa cells mediates apoptosis resistance through a Chlamydia protease-like activity factor-independent mechanism and induces high mobility group box 1 release.
Jürgen Rödel, Christina Grosse, Hangxing Yu, Katharina Wolf, Gordon P Otto

Infect Immun· January 2012

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The late phase of sepsis is characterized by an increased microbiological burden and death rate.
Gordon P Otto, Maik Sossdorf, Ralf A Claus, Jürgen Rödel, Katja Menge

Crit Care· July 2011

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