Publications by authors named "Grace H Chan"

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Evaluation of the Selectivity of Several Organic Anion Transporting Polypeptide 1B Biomarkers Using Relative Activity Factor Method.
Grace Hoyee Chan, Robert Houle, Jinghui Zhang, Ravi Katwaru, Yang Li

Drug Metab Dispos· September 2023

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In Vitro Assessment of Transporter Mediated Perpetrator DDIs for Several Hepatitis C Virus Direct-Acting Antiviral Drugs and Prediction of DDIs with Statins Using Static Models.
Xiaoyan Chu, Grace Hoyee Chan, Robert Houle, Meihong Lin, Jocelyn Yabut

AAPS J· March 2022

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Evaluation of the Drug Interaction Potential of Doravirine.
Kelly Bleasby, Kerry L Fillgrove, Robert Houle, Bing Lu, Jairam Palamanda, Grace Hoyee Chan

Antimicrob Agents Chemother· April 2019

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Identification of Endogenous Biomarkers to Predict the Propensity of Drug Candidates to Cause Hepatic or Renal Transporter-Mediated Drug-Drug Interactions.
Xiaoyan Chu, Grace Hoyee Chan, Raymond Evers

J Pharm Sci· September 2017

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The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes, Raymond Evers

Drug Metab Dispos· September 2016

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Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.
Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H Chan

Drug Metab Dispos· June 2015

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Raltegravir has a low propensity to cause clinical drug interactions through inhibition of major drug transporters: an in vitro evaluation.
Matthew L Rizk, Robert Houle, Grace Hoyee Chan, Mike Hafey, Elizabeth G Rhee

Antimicrob Agents Chemother· October 2014

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Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein.
Xiao-Yan Chu, Kelly Bleasby, Jocelyn Yabut, Xiaoxin Cai, Grace Hoyee Chan

J Pharmacol Exp Ther· May 2007

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