Publications by authors named "Graeme Alexander"

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Cost of hepatocellular carcinoma to the national health service in England: a registry-based analysis.
Katherine Cullen, Mari Jones, Rhys D Pockett, Anya Burton, Timothy J S Cross, Graeme Alexander

BMJ Open Gastroenterol· February 2023

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Role of Hepatocyte Senescence in the Activation of Hepatic Stellate Cells and Liver Fibrosis Progression.
Pramudi Wijayasiri, Stuart Astbury, Philip Kaye, Fiona Oakley, Graeme J Alexander

Cells· July 2022

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Investigation and management of Wilson's disease: a practical guide from the British Association for the Study of the Liver.
Samuel Shribman, Thomas Marjot, Abubakar Sharif, Sunitha Vimalesvaran, Aftab Ala, Graeme Alexander

Lancet Gastroenterol Hepatol· June 2022

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Regional variations in hepatocellular carcinoma incidence, routes to diagnosis, treatment and survival in England.
Anya Burton, Vinay K Balachandrakumar, Robert J Driver, Daniela Tataru, Lizz Paley, Graeme Alexander

Br J Cancer· March 2022

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Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1.
Ana Valencia, Candelaria Vergara, Chloe L Thio, Nicolas Vince, Venceslas Douillard, Graeme Alexander

Am J Hum Genet· February 2022

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A Multiancestry Sex-Stratified Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus.
Candelaria Vergara, Ana Valencia, Chloe L Thio, James J Goedert, Alessandra Mangia, Graeme Alexander

J Infect Dis· June 2021

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New dimensions for hospital services and early detection of disease: a Review from the Lancet Commission into liver disease in the UK.
Roger Williams, Charles Alessi, Graeme Alexander, Michael Allison, Richard Aspinall

Lancet· May 2021

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Primary liver cancer in the UK: Incidence, incidence-based mortality, and survival by subtype, sex, and nation.
Anya Burton, Daniela Tataru, Robert J Driver, Thomas G Bird, Dyfed Huws, Graeme Alexander

JHEP Rep· April 2021

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Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10.
Nicola E Owen, Duuamene Nyimanu, Rhoda E Kuc, Paul D Upton, Nicholas W Morrell, Graeme J Alexander

Peptides· February 2021

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Impact of a nurse-led enhanced monitoring, management and contact tracing intervention for chronic hepatitis B in England, 2015-2017.
Kazim Beebeejaun, Zahin Amin-Chowdhury, Louise Letley, Edna Kara, Beauty Mahange, Graeme Alexander

J Viral Hepat· January 2021

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Correction: Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection.
Candelaria Vergara, Priya Duggal, Chloe L Thio, Ana Valencia, Thomas R O'Brien, Graeme Alexander

Genes Immun· December 2020

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Multi-ancestry fine mapping of interferon lambda and the outcome of acute hepatitis C virus infection.
Candelaria Vergara, Priya Duggal, Chloe L Thio, Ana Valencia, Thomas R O'Brien, Graeme Alexander

Genes Immun· November 2020

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The Alpha-1 Antitrypsin Polymer Load Correlates With Hepatocyte Senescence, Fibrosis Stage and Liver-Related Mortality.
Marianna Mela, Wendy Smeeton, Susan E Davies, Elena Miranda, Cinzia Scarpini, Graeme J M Alexander

Chronic Obstr Pulm Dis· July 2020

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Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis.
Nicola E Owen, Graeme J Alexander, Sambit Sen, Katherine Bunclark, Gary Polwarth

EBioMedicine· June 2020

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Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK.
Roger Williams, Guruprasad Aithal, Graeme J Alexander, Michael Allison, Iain Armstrong

Lancet· January 2020

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British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis.
Michael Huw Chapman, Douglas Thorburn, Gideon M Hirschfield, George G J Webster, Simon M Rushbrook, Graeme Alexander

Gut· August 2019

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Pruritus Is Common and Undertreated in Patients With Primary Biliary Cholangitis in the United Kingdom.
Vinod S Hegade, George F Mells, Holly Fisher, Stuart Kendrick, Julia DiBello, Graeme J Alexander

Clin Gastroenterol Hepatol· June 2019

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Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System.
Elizabeth C Goode, Allan B Clark, George F Mells, Brijesh Srivastava, Kelly Spiess, Graeme J Alexander

Hepatology· May 2019

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Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus.
Candelaria Vergara, Chloe L Thio, Eric Johnson, Alex H Kral, Thomas R O'Brien, Graeme Alexander

Gastroenterology· April 2019

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Is the conquest of Hepatitis C imminent?
Lucy Rivett, Graeme Alexander

Expert Rev Mol Med· March 2019

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Gathering momentum for the way ahead: fifth report of the Lancet Standing Commission on Liver Disease in the UK.
Roger Williams, Graeme Alexander, Richard Aspinall, Rachel Batterham, Neeraj Bhala

Lancet· December 2018

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Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis.
Rebecca Darlay, Kristin L Ayers, George F Mells, Lynsey S Hall, Jimmy Z Liu, Graeme J Alexander

PLoS Genet· December 2018

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The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines.
Gideon M Hirschfield, Jessica K Dyson, Graeme J M Alexander, Michael H Chapman, Jane Collier

Gut· September 2018

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Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.
Marco Carbone, Alessandra Nardi, Steve Flack, Guido Carpino, Nikoletta Varvaropoulou, Graeme J Alexander

Lancet Gastroenterol Hepatol· September 2018

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imaging of hepatic neutrophil migration in severe alcoholic hepatitis with In-radiolabelled leucocytes.
Jonathan R Potts, Neda Farahi, Mark R Howard, Mark R Taylor, Sarah Heard, Graeme J Alexander

Biosci Rep· August 2018

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