Publications by authors named "Graham Allaway"

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Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist.
Priya Muralidharan, Brielle Jones, Graham Allaway, Shyam S Biswal, Heidi M Mansour

Sci Rep· November 2020

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Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative.
Jun Wei, Hongyan Zhu, Gabriel Lord, Mitra Bhattachayya, Brielle M Jones, Graham Allaway

Transl Res· May 2017

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Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy.
Nicole Lounsbury, George Mateo, Brielle Jones, Srinivas Papaiahgari, Rajash K Thimmulappa, Graham Allaway

Bioorg Med Chem· September 2015

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Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation.
Abdul S Yunus, Trent P Jackson, Katherine Crisafi, Irina Burimski, Nicole R Kilgore, Graham P Allaway

Virology· January 2010

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Susceptibility of human immunodeficiency virus type 1 to the maturation inhibitor bevirimat is modulated by baseline polymorphisms in Gag spacer peptide 1.
Kurt Van Baelen, Karl Salzwedel, Evelien Rondelez, Veerle Van Eygen, Stephanie De Vos, Graham P Allaway

Antimicrob Agents Chemother· May 2009

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Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.
Keduo Qian, Donglei Yu, Chin-Ho Chen, Li Huang, Susan L Morris-Natschke, Graham P Allaway

J Med Chem· May 2009

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Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection.
David E Martin, Karl Salzwedel, Graham P Allaway

Antivir Chem Chemother· December 2008

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Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives.
Keduo Qian, Kyoko Nakagawa-Goto, Donglei Yu, Susan L Morris-Natschke, Theodore J Nitz, Graham P Allaway

Bioorg Med Chem Lett· December 2007

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Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv mice.
Cheryl A Stoddart, Pheroze Joshi, Barbara Sloan, Jennifer C Bare, Philip C Smith, Graham P Allaway

PLoS One· November 2007

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Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection.
Patrick F Smith, Abayomi Ogundele, Alan Forrest, John Wilton, Karl Salzwedel, Graham P Allaway

Antimicrob Agents Chemother· October 2007

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Determinants of activity of the HIV-1 maturation inhibitor PA-457.
Feng Li, Dorian Zoumplis, Claudia Matallana, Nicole R Kilgore, Mary Reddick, Graham P Allaway

Virology· January 2007

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The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV.
Donglei Yu, Carl T Wild, David E Martin, Susan L Morris-Natschke, Chin-Ho Chen, Graham P Allaway

Expert Opin Investig Drugs· June 2005

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Computational studies and drug design for HIV-1 reverse transcriptase inhibitors of 3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogs.
Hai-Feng Chen, Bo-Tao Fan, Chen-Yang Zhao, Lan Xie, Chun-Hong Zhao, Graham Allaway

J Comput Aided Mol Des· April 2005

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3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents.
Yoshiki Kashiwada, Michiko Sekiya, Yasumasa Ikeshiro, Toshihiro Fujioka, Nicole R Kilgore, Graham P Allaway

Bioorg Med Chem Lett· December 2004

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Anti-AIDS agents. 52. Synthesis and anti-HIV activity of hydroxymethyl (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone derivatives.
Lan Xie, Donglei Yu, Carl Wild, Graham Allaway, Jim Turpin

J Med Chem· January 2004

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Direct evidence that C-peptide inhibitors of human immunodeficiency virus type 1 entry bind to the gp41 N-helical domain in receptor-activated viral envelope.
Nicole R Kilgore, Karl Salzwedel, Mary Reddick, Graham P Allaway, Carl T Wild

J Virol· July 2003

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Anti-HIV agents. Part 55: 3'R,4'R-Di-(O)-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP), a novel anti-HIV agent.
Donglei Yu, Arnold Brossi, Nicole Kilgore, Carl Wild, Graham Allaway

Bioorg Med Chem Lett· May 2003

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