Publications by authors named "Graham Coutts"

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Filter exchange imaging with crusher gradient modelling detects increased blood-brain barrier water permeability in response to mild lung infection.
Yolanda Ohene, William J Harris, Elizabeth Powell, Nina W Wycech, Katherine F Smethers, Samo Lasič, Kieron South, Graham Coutts, Andrew Sharp, Catherine B Lawrence

Fluids Barriers CNS· April 2023

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Comparison of the Novel Thrombolytic Constitutively Active ADAMTS13 With Clinical Thrombolytics in a Murine Stroke Model.
Lucy Roberts, Graham Coutts, Ben R Dickie, Craig J Smith, Kieron South

Stroke· June 2025

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The Role of the VWF/ADAMTS13 Axis in the Thromboinflammatory Response in Ischemic Stroke After SARS-CoV2 Infection.
Nadim Luka, Kieron South, Rachel Jones, Amanda J Unsworth, Graham Coutts

Brain Behav· February 2025

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Inhibition of neutrophil rolling and migration by caADAMTS13 in vitro and in mouse models of thrombosis and inflammation.
Kieron South, Lucy Roberts, Anna Gray, Nadim Luka, Patrick Strangward, Graham Coutts

Biomed Pharmacother· September 2024

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Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions.
Rose Wellens, Victor S Tapia, Paula I Seoane, Hayley Bennett, Antony Adamson, Graham Coutts

Nat Commun· August 2024

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Targeting firing rate neuronal homeostasis can prevent seizures.
Fred Mulroe, Wei-Hsiang Lin, Connie Mackenzie-Gray Scott, Najat Aourz, Yuen Ngan Fan, Graham Coutts

Dis Model Mech· October 2022

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Selective brain entry of lipid nanoparticles in haemorrhagic stroke is linked to biphasic blood-brain barrier disruption.
Zahraa S Al-Ahmady, Ben R Dickie, Isabelle Aldred, Dhifaf A Jasim, Jack Barrington, Graham Coutts

Theranostics· July 2022

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Robust thrombolytic and anti-inflammatory action of a constitutively active ADAMTS13 variant in murine stroke models.
Kieron South, Ohud Saleh, Eloise Lemarchand, Graham Coutts, Craig J Smith

Blood· March 2022

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Characterisation of microvessel blood velocity and segment length in the brain using multi-diffusion-time diffusion-weighted MRI.
Lauren A Scott, Ben R Dickie, Shelley D Rawson, Graham Coutts, Timothy L Burnett

J Cereb Blood Flow Metab· August 2021

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Selective Liposomal Transport through Blood Brain Barrier Disruption in Ischemic Stroke Reveals Two Distinct Therapeutic Opportunities.
Zahraa S Al-Ahmady, Dhifaf Jasim, Sabahuddin Syed Ahmad, Raymond Wong, Michael Haley, Graham Coutts

ACS Nano· November 2019

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Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome.
Eloise Lemarchand, Jack Barrington, Alistair Chenery, Michael Haley, Graham Coutts

Stroke· May 2019

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Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.
Raymond Wong, Nikolett Lénárt, Laura Hill, Lauren Toms, Graham Coutts

Brain Behav Immun· February 2019

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Neutrophil infiltration to the brain is platelet-dependent, and is reversed by blockade of platelet GPIbα.
James A Giles, Andrew D Greenhalgh, Adam Denes, Bernhard Nieswandt, Graham Coutts

Immunology· June 2018

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Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia.
Jesus M Pradillo, Katie N Murray, Graham A Coutts, Ana Moraga, Fernando Oroz-Gonjar

Brain Behav Immun· March 2017

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IL-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination.
Ewa Oleszycka, Hannah B T Moran, Graham A Tynan, Claire H Hearnden, Graham Coutts

FEBS J· January 2016

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AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.
Adam Denes, Graham Coutts, Nikolett Lénárt, Sheena M Cruickshank, Pablo Pelegrin

Proc Natl Acad Sci U S A· March 2015

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Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity.
James A Giles, Andrew D Greenhalgh, Claire L Davies, Adam Denes, Tovah Shaw, Graham Coutts

Eur J Immunol· February 2015

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Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α-dependent inflammation.
Graham A Tynan, Claire H Hearnden, Ewa Oleszycka, Claire L Lyons, Graham Coutts

Diabetes· June 2014

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Effects of TWIN-OF-EYELESS on Clock Gene Expression and Central-Pacemaker Neuron Development in Drosophila.
Nicholas R J Glossop, Jennet O Gummadova, Indrayani Ghangrekar, Paul E Hardin, Graham A Coutts

J Biol Rhythms· June 2014

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Recombinant tissue plasminogen activator enhances microglial cell recruitment after stroke in mice.
Sébastien Lenglet, Fabrizio Montecucco, Adam Denes, Graham Coutts, Emmanuel Pinteaux

J Cereb Blood Flow Metab· May 2014

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Analysis of the Drosophila Clock promoter reveals heterogeneity in expression between subgroups of central oscillator cells and identifies a novel enhancer region.
Jennet Orazmuradovna Gummadova, Graham Andrew Coutts, Nicholas Robert John Glossop

J Biol Rhythms· October 2009

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Catalase (KatA) and alkyl hydroperoxide reductase (AhpC) have compensatory roles in peroxide stress resistance and are required for survival, persistence, and nasal colonization in Staphylococcus aureus.
Kate Cosgrove, Graham Coutts, Ing-Marie Jonsson, Andrej Tarkowski, John F Kokai-Kun

J Bacteriol· February 2007

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Purification of the Escherichia coli ammonium transporter AmtB reveals a trimeric stoichiometry.
Dan Blakey, Andrew Leech, Gavin H Thomas, Graham Coutts, Kim Findlay

Biochem J· June 2002

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Membrane sequestration of the signal transduction protein GlnK by the ammonium transporter AmtB.
Graham Coutts, Gavin Thomas, Dan Blakey, Mike Merrick

EMBO J· February 2002

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