Publications by authors named "Graham Jang"

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Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease.
Edmund C Lee, Tania Valencia, Charles Allerson, Annelie Schairer, Andrea Flaten, Graham Jang

Nat Commun· September 2019

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Population PK and Exposure-Response Relationships for the Antibody-Drug Conjugate Brentuximab Vedotin in CTCL Patients in the Phase III ALCANZA Study.
Ajit Suri, Diane R Mould, Yi Liu, Graham Jang, Karthik Venkatakrishnan

Clin Pharmacol Ther· November 2018

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Population Pharmacokinetics of Brentuximab Vedotin in Patients With CD30-Expressing Hematologic Malignancies.
Hong Li, Tae H Han, Naomi N Hunder, Graham Jang, Baiteng Zhao

J Clin Pharmacol· September 2017

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The pharmacokinetics and pharmacodynamics of denosumab in patients with advanced solid tumours and bone metastases: a systematic review.
Winnie Sohn, Mary Ann Simiens, Kelly Jaeger, Shauna Hutton, Graham Jang

Br J Clin Pharmacol· September 2014

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A clinical therapeutic protein drug-drug interaction study: coadministration of denosumab and midazolam in postmenopausal women with osteoporosis.
Graham Jang, Allegra Kaufman, Edward Lee, Lisa Hamilton, Shauna Hutton

Pharmacol Res Perspect· April 2014

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Multiple doses of sclerostin antibody romosozumab in healthy men and postmenopausal women with low bone mass: a randomized, double-blind, placebo-controlled study.
Desmond Padhi, Mark Allison, Alan J Kivitz, Maria J Gutierrez, Brian Stouch, Graham Jang

J Clin Pharmacol· February 2014

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Denosumab dose selection for patients with bone metastases from solid tumors.
Sameer Doshi, Liviawati Sutjandra, Jenny Zheng, Winnie Sohn, Mark Peterson, Graham Jang

Clin Cancer Res· May 2012

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Population pharmacokinetic analysis of denosumab in patients with bone metastases from solid tumours.
Leonid Gibiansky, Liviawati Sutjandra, Sameer Doshi, Jenny Zheng, Winnie Sohn, Graham R Jang

Clin Pharmacokinet· April 2012

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Population pharmacokinetic meta-analysis of denosumab in healthy subjects and postmenopausal women with osteopenia or osteoporosis.
Liviawati Sutjandra, Rachelle D Rodriguez, Sameer Doshi, Mark Ma, Mark C Peterson, Graham R Jang

Clin Pharmacokinet· December 2011

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Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody.
Desmond Padhi, Graham Jang, Brian Stouch, Liang Fang, Edward Posvar

J Bone Miner Res· January 2011

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Investigation of the effects of altered receptor binding activity on the clearance of erythropoiesis-stimulating proteins: Nonerythropoietin receptor-mediated pathways may play a major role.
Balaji Agoram, Ken Aoki, Sameer Doshi, Colin Gegg, Graham Jang

J Pharm Sci· June 2009

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Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans.
Narender R Gavva, James J S Treanor, Andras Garami, Liang Fang, Sekhar Surapaneni, Graham R Jang

Pain· May 2008

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Drug interactions involving ethanol and alcoholic beverages.
Graham R Jang, Robert Z Harris

Expert Opin Drug Metab Toxicol· October 2007

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Pharmacology of darbepoetin alfa.
Iain C Macdougall, Desmond Padhi, Graham Jang

Nephrol Dial Transplant· June 2007

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An extended terminal half-life for darbepoetin alfa: results from a single-dose pharmacokinetic study in patients with chronic kidney disease not receiving dialysis.
Desmond Padhi, Liyun Ni, Blaire Cooke, Rafael Marino, Graham Jang

Clin Pharmacokinet· October 2006

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Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization.
William C Rose, Punit H Marathe, Graham R Jang, Thomas M Monticello, Balu N Balasubramanian

Cancer Chemother Pharmacol· July 2006

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Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase.
Nuria Tamayo, Lillian Liao, Martin Goldberg, David Powers, Yan-Yan Tudor, Graham Jang

Bioorg Med Chem Lett· May 2005

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Dietary effects on drug metabolism and transport.
Robert Z Harris, Graham R Jang, Shirley Tsunoda

Clin Pharmacokinet· March 2004

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