Publications by authors named "Graham M Wheeler"

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"Improving the performance of Bayesian logistic regression model with overdose control in oncology dose-finding studies" by Hongtao Zhang, Alan Chiang, and Jixian Wang.
Alexia Iasonos, Graham M Wheeler

Stat Med· November 2022

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Effectiveness and cost-effectiveness of referral to a commercial open group behavioural weight management programme in adults with overweight and obesity: 5-year follow-up of the WRAP randomised controlled trial.
Amy L Ahern, Penny Breeze, Francesco Fusco, Stephen J Sharp, Nazrul Islam, Graham M Wheeler

Lancet Public Health· October 2022

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The effect of referral to an open-group behavioural weight-management programme on the relative risk of normoglycaemia, non-diabetic hyperglycaemia and type 2 diabetes: Secondary analysis of the WRAP trial.
Amy L Ahern, Simon J Griffin, Graham M Wheeler, Stephen J Sharp, Paul Aveyard

Diabetes Obes Metab· November 2020

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Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs.
Thomas Burnett, Pavel Mozgunov, Philip Pallmann, Sofia S Villar, Graham M Wheeler

BMC Med· November 2020

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Ganetespib in Combination with Pemetrexed-Platinum Chemotherapy in Patients with Pleural Mesothelioma (MESO-02): A Phase Ib Trial.
Dean A Fennell, Sarah Danson, Penella J Woll, Martin Forster, Denis Talbot, Graham M Wheeler

Clin Cancer Res· September 2020

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A review of available software for adaptive clinical trial design.
Michael John Grayling, Graham Mark Wheeler

Clin Trials· June 2020

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Designing and evaluating dose-escalation studies made easy: The MoDEsT web app.
Philip Pallmann, Fang Wan, Adrian P Mander, Graham M Wheeler, Christina Yap

Clin Trials· April 2020

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A Bayesian model-free approach to combination therapy phase I trials using censored time-to-toxicity data.
Graham M Wheeler, Michael J Sweeting, Adrian P Mander

J R Stat Soc Ser C Appl Stat· February 2019

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How to design a dose-finding study using the continual reassessment method.
Graham M Wheeler, Adrian P Mander, Alun Bedding, Kristian Brock, Victoria Cornelius

BMC Med Res Methodol· January 2019

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Incoherent dose-escalation in phase I trials using the escalation with overdose control approach.
Graham M Wheeler

Stat Pap (Berl)· June 2018

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Adaptive designs in clinical trials: why use them, and how to run and report them.
Philip Pallmann, Alun W Bedding, Babak Choodari-Oskooei, Munyaradzi Dimairo, Laura Flight, Graham M Wheeler

BMC Med· February 2018

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AplusB: A Web Application for Investigating A + B Designs for Phase I Cancer Clinical Trials.
Graham M Wheeler, Michael J Sweeting, Adrian P Mander

PLoS One· July 2017

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Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials.
Graham M Wheeler, Michael J Sweeting, Adrian P Mander

Stat Med· July 2017

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Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial.
Amy L Ahern, Graham M Wheeler, Paul Aveyard, Emma J Boyland, Jason C G Halford

Lancet· June 2017

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Modelling semi-attributable toxicity in dual-agent phase I trials with non-concurrent drug administration.
Graham M Wheeler, Michael J Sweeting, Adrian P Mander, Shing M Lee, Ying Kuen K Cheung

Stat Med· January 2017

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Adaptive designs for dual-agent phase I dose-escalation studies.
Jennifer A Harrington, Graham M Wheeler, Michael J Sweeting, Adrian P Mander, Duncan I Jodrell

Nat Rev Clin Oncol· May 2013

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