Publications by authors named "Grazia Raffa"

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Mutational analysis of the Drosophila CMG helicase reveals relationships among chromosome integrity and the maintenance of spindle and centrosome structure.
Lucia Graziadio, Livia Scatolini, Elisabetta Bucciarelli, Grazia Daniela Raffa, Silvia Bonaccorsi

Genetics· September 2025

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Maintaining Telomeres without Telomerase in : Novel Mechanisms and Rapid Evolution to Save a Genus.
Stefano Cacchione, Giovanni Cenci, Anne-Marie Dion-Côté, Daniel A Barbash, Grazia Daniela Raffa

Cold Spring Harb Perspect Biol· March 2025

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Correction to: 'The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence' (2016), by Burla .
Romina Burla, Mariateresa Carcuro, Mattia La Torre, Federica Fratini, Marco Crescenzi, Grazia Daniela Raffa

Open Biol· November 2024

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TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.
Lu Chen, Caitlin M Roake, Paolo Maccallini, Francesca Bavasso, Roozbeh Dehghannasiri, Grazia D Raffa

Nucleic Acids Res· November 2022

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TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance.
Valentina Buemi, Odessa Schillaci, Mariangela Santorsola, Deborah Bonazza, Pamela Veneziano Broccia, Grazia Daniela Raffa

Nat Commun· April 2022

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The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening.
Alessandra Galati, Livia Scatolini, Emanuela Micheli, Francesca Bavasso, Alessandro Cicconi, Grazia D Raffa

FEBS Lett· January 2022

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Atomic Force Microscopy Reveals that the Drosophila Telomere-Capping Protein Verrocchio Is a Single-Stranded DNA-Binding Protein.
Alessandro Cicconi, Emanuela Micheli, Grazia Daniela Raffa, Stefano Cacchione

Methods Mol Biol· June 2021

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Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements.
Stefano Cacchione, Giovanni Cenci, Grazia Daniela Raffa

J Mol Biol· July 2020

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Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development.
Paolo Maccallini, Francesca Bavasso, Livia Scatolini, Elisabetta Bucciarelli, Gemma Noviello, Grazia Daniela Raffa

PLoS Genet· May 2020

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Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation.
Lu Chen, Caitlin M Roake, Alessandra Galati, Francesca Bavasso, Emanuela Micheli, Grazia D Raffa

Cell Rep· February 2020

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Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
Caitlin M Roake, Lu Chen, Ananya L Chakravarthy, James E Ferrell, Grazia D Raffa

Mol Cell· May 2019

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WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models.
Maria Laura Di Giorgio, Alessandro Esposito, Paolo Maccallini, Emanuela Micheli, Francesca Bavasso, Grazia Daniela Raffa

Neurobiol Dis· September 2017

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The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response.
Alessandro Cicconi, Emanuela Micheli, Fiammetta Vernì, Alison Jackson, Ana Citlali Gradilla, Grazia Daniela Raffa

Nucleic Acids Res· April 2017

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The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.
Romina Burla, Mariateresa Carcuro, Mattia La Torre, Federica Fratini, Marco Crescenzi, Grazia Daniela Raffa

Open Biol· August 2016

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A role for Separase in telomere protection.
Francesca Cipressa, Patrizia Morciano, Giuseppe Bosso, Linda Mannini, Alessandra Galati, Grazia Daniela Raffa

Nat Commun· January 2016

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AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance.
Romina Burla, Mariateresa Carcuro, Grazia D Raffa, Alessandra Galati, Domenico Raimondo

PLoS Genet· June 2015

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The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres.
Giovanni Cenci, Laura Ciapponi, Marta Marzullo, Grazia D Raffa, Patrizia Morciano

PLoS Genet· June 2015

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GOLPH3 is essential for contractile ring formation and Rab11 localization to the cleavage site during cytokinesis in Drosophila melanogaster.
Stefano Sechi, Gianni Colotti, Giorgio Belloni, Vincenzo Mattei, Anna Frappaolo, Grazia D Raffa

PLoS Genet· May 2014

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Organization and Evolution of Drosophila Terminin: Similarities and Differences between Drosophila and Human Telomeres.
Grazia D Raffa, Giovanni Cenci, Laura Ciapponi, Maurizio Gatti

Front Oncol· May 2013

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Terminin: a protein complex that mediates epigenetic maintenance of Drosophila telomeres.
Grazia D Raffa, Laura Ciapponi, Giovanni Cenci, Maurizio Gatti

Nucleus· March 2012

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Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex.
Grazia D Raffa, Domenico Raimondo, Cristina Sorino, Simona Cugusi, Giovanni Cenci

Genes Dev· August 2010

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Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc.
Jochen Abel, Ragnhild Eskeland, Grazia D Raffa, Elisabeth Kremmer, Axel Imhof

PLoS One· July 2009

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The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection.
Grazia D Raffa, Giorgia Siriaco, Simona Cugusi, Laura Ciapponi, Giovanni Cenci

Proc Natl Acad Sci U S A· February 2009

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Autosomal mutations affecting Y chromosome loops in Drosophila melanogaster.
Francesca Ceprani, Grazia D Raffa, Romano Petrucci, Roberto Piergentili

BMC Genet· April 2008

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SUMO-targeted ubiquitin ligases in genome stability.
John Prudden, Stephanie Pebernard, Grazia Raffa, Daniela A Slavin, J Jefferson P Perry

EMBO J· September 2007

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