Publications by authors named "Greg Brennan"

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Molecular Determinants of Species-Specific Interactions Between Protein Kinase R and Poxvirus K3 Orthologs.
Chorong Park, Greg Brennan, Chen Peng, Chi Zhang, Jingxin Cao

Viruses· November 2025

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Poxvirus K3 Orthologs Regulate NF-κB-Dependent Inflammatory Responses by Targeting the PKR-eIF2α Axis in Multiple Species.
Huibin Yu, Mary Eloise L Fernandez, Chen Peng, Dewi Megawati, Greg Brennan

Vaccines (Basel)· July 2025

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Experimental Evolution of Poxviruses.
Shefali Banerjee, Kelsea A Jewell, Greg Brennan

Methods Mol Biol· December 2024

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Host species-specific activity of the poxvirus PKR inhibitors E3 and K3 mediate host range function.
Sherry L Haller, Chorong Park, Ryan C Bruneau, Dewi Megawati, Chi Zhang, Greg Brennan

J Virol· November 2024

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Tanapox Virus and Yaba Monkey Tumor Virus K3 Orthologs Inhibit Primate Protein Kinase R in a Species-Specific Fashion.
Dewi Megawati, Jeannine N Stroup, Chorong Park, Taylor Clarkson, Loubna Tazi, Greg Brennan

Viruses· July 2024

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Molecular basis for the host range function of the poxvirus PKR inhibitor E3.
Sherry L Haller, Chorong Park, Ryan C Bruneau, Dewi Megawati, Chi Zhang, Greg Brennan

bioRxiv· May 2024

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Molecular Mechanisms of Poxvirus Evolution.
Greg Brennan, Ana M M Stoian, Huibin Yu, M Julhasur Rahman, Shefali Banerjee

mBio· February 2023

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Adaptive duplication and genetic diversification of protein kinase R contribute to the specificity of bat-virus interactions.
Stéphanie Jacquet, Michelle Culbertson, Chi Zhang, Adil El Filali, Clément De La Myre Mory, Greg Brennan

Sci Adv· November 2022

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Gene amplification acts as a molecular foothold to facilitate cross-species adaptation and evasion of multiple antiviral pathways.
Shefali Banerjee, Cathy Smith, Adam P Geballe, Stefan Rothenburg, Jacob O Kitzman, Greg Brennan

Virus Evol· November 2022

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Gene amplification acts as a molecular foothold to facilitate cross-species adaptation and evasion of multiple antiviral pathways.
Shefali Banerjee, Cathy Smith, Adam Geballe, Stefan Rothenburg, Jacob O Kitzman, Greg Brennan

bioRxiv· October 2022

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LINE-1 retrotransposons facilitate horizontal gene transfer into poxviruses.
M Julhasur Rahman, Sherry L Haller, Ana M M Stoian, Jie Li, Greg Brennan

Elife· September 2022

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Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway.
Huibin Yu, Chen Peng, Chi Zhang, Ana M M Stoian, Loubna Tazi, Greg Brennan

Proc Natl Acad Sci U S A· May 2022

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SARS-CoV-2 detection and genomic sequencing from hospital surface samples collected at UC Davis.
David A Coil, Timothy Albertson, Shefali Banerjee, Greg Brennan, A J Campbell

PLoS One· July 2021

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Battle Royale: Innate Recognition of Poxviruses and Viral Immune Evasion.
Huibin Yu, Ryan C Bruneau, Greg Brennan, Stefan Rothenburg

Biomedicines· July 2021

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Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR.
Chorong Park, Chen Peng, M Julhasur Rahman, Sherry L Haller, Loubna Tazi, Greg Brennan

PLoS Pathog· January 2021

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Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection.
Sameera Vipat, Greg Brennan, Chorong Park, Sherry L Haller, Stefan Rothenburg

J Vis Exp· May 2020

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Species-Specific Host-Virus Interactions: Implications for Viral Host Range and Virulence.
Stefan Rothenburg, Greg Brennan

Trends Microbiol· January 2020

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Species-specific inhibition of antiviral protein kinase R by capripoxviruses and vaccinia virus.
Chorong Park, Chen Peng, Greg Brennan, Stefan Rothenburg

Ann N Y Acad Sci· February 2019

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Adaptation by copy number variation in monopartite viruses.
Avraham Bayer, Greg Brennan, Adam P Geballe

Curr Opin Virol· December 2018

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Experimental Evolution Identifies Vaccinia Virus Mutations in A24R and A35R That Antagonize the Protein Kinase R Pathway and Accompany Collapse of an Extragenic Gene Amplification.
Greg Brennan, Jacob O Kitzman, Jay Shendure, Adam P Geballe

J Virol· October 2015

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Adaptive gene amplification as an intermediate step in the expansion of virus host range.
Greg Brennan, Jacob O Kitzman, Stefan Rothenburg, Jay Shendure, Adam P Geballe

PLoS Pathog· March 2014

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Species specificity of protein kinase r antagonism by cytomegalovirus TRS1 genes.
Stephanie J Child, Greg Brennan, Jacquelyn E Braggin, Adam P Geballe

J Virol· April 2012

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Variable prevalence and functional diversity of the antiretroviral restriction factor TRIMCyp in Macaca fascicularis.
Elizabeth A Dietrich, Greg Brennan, Betsy Ferguson, Roger W Wiseman, David O'Connor

J Virol· October 2011

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TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis.
Greg Brennan, Yury Kozyrev, Shiu-Lok Hu

Proc Natl Acad Sci U S A· March 2008

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Novel TRIM5 isoforms expressed by Macaca nemestrina.
Greg Brennan, Yury Kozyrev, Toshiaki Kodama, Shiu-Lok Hu

J Virol· November 2007

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