Publications by authors named "Greg Springsteen"

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Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways.
Sunil Pulletikurti, Mahipal Yadav, Greg Springsteen, Ramanarayanan Krishnamurthy

Nat Chem· October 2022

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From Amino Acids to α-Keto Acids via β-Elimination and Transamination Initiates a Pathway to Prebiotic Reaction Networks.
Louis M P Ter-Ovanessian, Kate L Ryan, Joshua Shaarda, R Trent Stubbs, Ramanarayanan Krishnamurthy, Greg Springsteen

Angew Chem Int Ed Engl· July 2025

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A Plausible Prebiotic One-Pot Synthesis of Orotate and Pyruvate Suggestive of Common Protometabolic Pathways.
Alyssa P Clay, Rachel E Cooke, Ravi Kumar, Mahipal Yadav, Ramanarayanan Krishnamurthy, Greg Springsteen

Angew Chem Int Ed Engl· March 2022

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A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids.
R Trent Stubbs, Mahipal Yadav, Ramanarayanan Krishnamurthy, Greg Springsteen

Nat Chem· November 2020

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The Messy Alkaline Formose Reaction and Its Link to Metabolism.
Arthur Omran, Cesar Menor-Salvan, Greg Springsteen, Matthew Pasek

Life (Basel)· July 2020

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Synthesis of 2-Thioorotidine and Comparison of Its Unusual Instability with Its Canonical Pyrimidine Counterparts.
Ravi Kumar, Greg Springsteen, Ramanarayanan Krishnamurthy

J Org Chem· November 2019

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Linked cycles of oxidative decarboxylation of glyoxylate as protometabolic analogs of the citric acid cycle.
Greg Springsteen, Jayasudhan Reddy Yerabolu, Julia Nelson, Chandler Joel Rhea, Ramanarayanan Krishnamurthy

Nat Commun· January 2018

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Reaching Back to Jump Forward: Recent Efforts towards a Systems-Level Hypothesis for an Early RNA World.
Greg Springsteen

Chembiochem· July 2015

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From formamide to adenine: a self-catalytic mechanism for an abiotic approach.
Jing Wang, Jiande Gu, Minh Tho Nguyen, Greg Springsteen, Jerzy Leszczynski

J Phys Chem B· November 2013

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From formamide to purine: a self-catalyzed reaction pathway provides a feasible mechanism for the entire process.
Jing Wang, Jiande Gu, Minh Tho Nguyen, Greg Springsteen, Jerzy Leszczynski

J Phys Chem B· August 2013

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From formamide to purine: an energetically viable mechanistic reaction pathway.
Jing Wang, Jiande Gu, Minh Tho Nguyen, Greg Springsteen, Jerzy Leszczynski

J Phys Chem B· February 2013

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A unified mechanism for abiotic adenine and purine synthesis in formamide.
Jeremy S Hudson, Joseph F Eberle, Raj H Vachhani, Luther C Rogers, James H Wade, Greg Springsteen

Angew Chem Int Ed Engl· May 2012

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Conversion of a ribozyme to a deoxyribozyme through in vitro evolution.
Natasha Paul, Greg Springsteen, Gerald F Joyce

Chem Biol· March 2006

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Regulating the fluorescence intensity of an anthracene boronic acid system: a B-N bond or a hydrolysis mechanism?
Weijuan Ni, Gurpreet Kaur, Greg Springsteen, Binghe Wang, Stefan Franzen

Bioorg Chem· December 2004

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Selective derivatization and sequestration of ribose from a prebiotic mix.
Greg Springsteen, Gerald F Joyce

J Am Chem Soc· August 2004

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The design of boronic acid spectroscopic reporter compounds by taking advantage of the pK(a)-lowering effect of diol binding: nitrophenol-based color reporters for diols.
Weijuan Ni, Hao Fang, Greg Springsteen, Binghe Wang

J Org Chem· March 2004

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A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH.
Wenqian Yang, Jun Yan, Greg Springsteen, Susan Deeter, Binghe Wang

Bioorg Med Chem Lett· March 2003

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