Publications by authors named "Gregory Bird"

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A triple-action PROTAC for wild-type p53 cancer therapy.
Gregory H Bird, Utsarga Adhikary, Michael J Schmidt, Marina Godes, Bethany Tesar

Cell Rep Med· December 2025

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Inhibition of oligomeric BAX by an anti-apoptotic dimer.
Catherine E Newman, Micah A Gygi, Haleh Alimohamadi, Thomas M DeAngelo, Christina M Camara, Gregory H Bird

Cell· November 2025

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Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices.
Thomas M DeAngelo, Utsarga Adhikary, Kyle J Korshavn, Hyuk-Soo Seo, Clara R Brotzen-Smith, Gregory H Bird

Nat Commun· September 2025

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Targeting NEDD9-SH3 with a Covalent Peptide Controls Endothelial Phenotype.
Andriy O Samokhin, Hyuk-Soo Seo, Alison Leed, Behnoush Hajian, Gregory H Bird

bioRxiv· July 2025

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Dissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor.
Sophia X Tang, Christina M Camara, Joy A Franco, Maria F Pazyra-Murphy, Yihang Li, Gregory H Bird

Cell Chem Biol· October 2024

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A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential.
Gregory H Bird, J J Patten, William Zavadoski, Nicole Barucci, Marina Godes

Nat Commun· January 2024

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Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.
Katrina M Hawley, Rachel J Eclov, Mathew R Schnorenberg, Yu Tian, Rhea N Shah, Gregory H Bird

Proc Natl Acad Sci U S A· October 2022

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Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency.
Michelle S Prew, Christina M Camara, Thomas Botzanowski, Jamie A Moroco, Noah B Bloch, Gregory H Bird

Nat Commun· June 2022

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Generation of Potent and Stable GLP-1 Analogues Via "Serine Ligation".
Paul M Levine, Timothy W Craven, Xinting Li, Aaron T Balana, Gregory H Bird

ACS Chem Biol· April 2022

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Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets.
Accalia Fu, Lara van Rooyen, Lindsay Evans, Nina Armstrong, Daina Avizonis, Gregory H Bird

Cell Rep· November 2021

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Characterizing Native and Hydrocarbon-Stapled Enfuvirtide Conformations with Ion Mobility Mass Spectrometry and Hydrogen-Deuterium Exchange.
Bradley B Stocks, Gregory H Bird, Loren D Walensky, Jeremy E Melanson

J Am Soc Mass Spectrom· March 2021

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Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival.
Yusuke Fukuda, Maria F Pazyra-Murphy, Elizabeth S Silagi, Ozge E Tasdemir-Yilmaz, Yihang Li, Gregory H Bird

J Cell Biol· January 2021

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Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer.
Ann M Cathcart, Gregory H Bird, Thomas E Wales, Henry D Herce, Edward P Harvey

Nat Chem Biol· November 2020

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A redox switch regulates the structure and function of anti-apoptotic BFL-1.
Kyle J Korshavn, Thomas E Wales, Gregory H Bird, John R Engen, Loren D Walensky

Nat Struct Mol Biol· September 2020

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Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.
Gregory H Bird, Accalia Fu, Silvia Escudero, Marina Godes, Kwadwo Opoku-Nsiah

ACS Chem Biol· June 2020

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Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.
Edward P Harvey, Zachary J Hauseman, Daniel T Cohen, T Justin Rettenmaier, Susan Lee, Gregory H Bird

Cell Chem Biol· June 2020

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Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation.
Accalia Fu, Juan Carlos Alvarez-Perez, Daina Avizonis, Tatsuya Kin, Scott B Ficarro, Gregory H Bird

Nat Metab· May 2020

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MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors.
Thomas P Howard, Taylor E Arnoff, Melinda R Song, Andrew O Giacomelli, Xiaofeng Wang, Gregory H Bird

Cancer Res· May 2019

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Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer.
Rachel M Guerra, Gregory H Bird, Edward P Harvey, Neekesh V Dharia, Kyle J Korshavn

Cell Rep· September 2018

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Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in wild-type Ewing sarcoma.
Björn Stolte, Amanda Balboni Iniguez, Neekesh V Dharia, Amanda L Robichaud, Amy Saur Conway, Gregory H Bird

J Exp Med· August 2018

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Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD.
Silvia Escudero, Elma Zaganjor, Susan Lee, Christopher P Mill, Ann M Morgan, Gregory H Bird

Mol Cell· March 2018

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Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.
Edward P Harvey, Hyuk-Soo Seo, Rachel M Guerra, Gregory H Bird, Sirano Dhe-Paganon

Structure· January 2018

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Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Raheleh Rezaei Araghi, Gregory H Bird, Jeremy A Ryan, Justin M Jenson, Marina Godes

Proc Natl Acad Sci U S A· January 2018

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Paclitaxel Reduces Axonal Bclw to Initiate IPR1-Dependent Axon Degeneration.
Sarah E Pease-Raissi, Maria F Pazyra-Murphy, Yihang Li, Franziska Wachter, Yusuke Fukuda, Gregory H Bird

Neuron· October 2017

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The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes.
Nicholas R Casewell, Jeroen C Visser, Kate Baumann, James Dobson, Han Han, Gregory C Bird

Curr Biol· May 2017

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