Publications by authors named "Gregory Ciszewski"

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Cyclic Peptide C5aR1 Antagonist Design Using Solution Conformational Analysis Derived from Residual Dipolar Couplings.
Kathleen A Farley, Ye Che, Ricardo Lira, Peter Jones, Nikolaos Papaioannou, Gregory Ciszewski

ACS Med Chem Lett· November 2024

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An Automated Purification Workflow Coupled with Material-Sparing High-Throughput H NMR for Parallel Medicinal Chemistry.
Justin Bellenger, Martin R M Koos, Melissa Avery, Mark Bundesmann, Gregory Ciszewski

ACS Med Chem Lett· September 2024

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Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure-Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H Receptor Inverse Agonist.
Manjinder S Lall, Asser Bassyouni, James Bradow, Maria Brown, Mark Bundesmann, Gregory Ciszewski

J Med Chem· July 2020

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Synthesis of pyrazolo[1,5-alpha]pyrimidinone regioisomers.
Lori K Gavrin, Arthur Lee, Brian A Provencher, Walter W Massefski, Stephen D Huhn, Gregory M Ciszewski

J Org Chem· February 2007

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Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.
Ariamala Gopalsamy, Rajiv Chopra, Kitae Lim, Gregory Ciszewski, Mengxiao Shi

J Med Chem· June 2006

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Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.
Ariamala Gopalsamy, Mengxiao Shi, Gregory Ciszewski, Kaapjoo Park, John W Ellingboe

Bioorg Med Chem Lett· May 2006

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Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.
Ariamala Gopalsamy, Alexis Aplasca, Gregory Ciszewski, Kaapjoo Park, John W Ellingboe

Bioorg Med Chem Lett· January 2006

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Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.
Ariamala Gopalsamy, Kitae Lim, Gregory Ciszewski, Kaapjoo Park, John W Ellingboe

J Med Chem· December 2004

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