Publications by authors named "Gregory Cook"

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Advancing the antituberculosis activity of nitropicolinic acids and amides.
Andrew M Thompson, Chen-Yi Cheung, Matthew B McNeil, Ashley C Campbell, Monika Záhorszká, Gregory M Cook

Eur J Med Chem· January 2026

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Prolonged exposure to teixobactin generates cross-tolerance to other cell wall-targeting antimicrobials in .
Rachel L Darnell, Melanie K Knottenbelt, Olivia E Rose, Caitlin S B Cleary, Francesca O Todd Rose, Gregory M Cook

Antimicrob Agents Chemother· December 2025

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Primary Prevention of Clostridioides difficile Infection With Oral Vancomycin in Pediatric Hematopoietic Stem Cell Transplant Patients.
Heather Valdin, Blake Gray, Gregory Cook, Mackenzie Creamer, Lolie Yu

Pediatr Transplant· December 2025

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Design, synthesis and biological activity of potential retrometabolic polymyxins thiol-ene chemistry.
Catherine Smith, Andrew Siow, Renata Kowalczyk, Scott A Ferguson, Matigan J B Smith, Gregory M Cook

Chem Commun (Camb)· December 2025

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Perinatal fentanyl exposure drives enduring addiction risk and central amygdala gene dysregulation.
Courtney P Wood, Yeji Shin, Maria G Balaguer, Paola Campo, Selen Dirik, Gregory M R Cook

Neuropharmacology· November 2025

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Beyond the "2 + 2 Pharmacophore" Electronic and Hydrophobic Effects Control the Activity of Cationic Amphiphilic Antimicrobial 2,5-Diketopiperazines.
Christy Siu, Tashia Siew, Freda F Li, Sonya Mros, Caitlin S B Cleary, Gregory M Cook

J Med Chem· November 2025

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ClpC1 Modulating Ohmyungsamycin A and Ecumicin Natural Product Analogues are Potent Antimycobacterials.
Paige M E Hawkins, Max J Bedding, David M Hoi, Isabel K Barter, Chen-Yi Cheung, Gregory M Cook

ACS Infect Dis· November 2025

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Remission spectroscopy resolves the mechanism of action of bedaquiline within living mycobacteria.
Suzanna H Harrison, Rowan C Walters, Chen-Yi Cheung, Roger J Springett, Gregory M Cook

Nat Commun· November 2025

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Comparative genomics of endemic ST1 in New Zealand.
Emma M Voss, Gregory M Cook, Christine Couldrey, Scott A Ferguson, Chad Harland

mSphere· October 2025

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Cannabidiol mitigates alcohol dependence and withdrawal with neuroprotective effects in the basolateral amygdala and striatum.
Selen Dirik, Michelle R Doyle, Courtney P Wood, Paola Campo, Angelica R Martinez, Gregory M R Cook

Neuropsychopharmacology· July 2025

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ATP synthesis driven by atmospheric hydrogen concentrations.
Sarah Soom, Stefan Urs Moning, Gregory M Cook, James P Lingford, Ashleigh Kropp

Proc Natl Acad Sci U S A· July 2025

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Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis.
Zhiqi Xiong, Xiaolin Yang, Shule Wang, Caitlan J Smart, Hazel M Sisson, Gregory M Cook

Nat Commun· May 2025

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Perinatal Fentanyl Exposure Drives Enduring Addiction Risk and Central Amygdala Gene Dysregulation.
Courtney P Wood, Yeji Shin, Maria G Balaguer, Paola Campo, Selen Dirik, Gregory M R Cook

bioRxiv· May 2025

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Structure of Mycobacterial NDH-2 Bound to a 2-Mercapto-Quinazolinone Inhibitor.
Yingke Liang, Stephanie A Bueler, Gregory M Cook, John L Rubinstein

J Med Chem· April 2025

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Verapamil and its metabolite norverapamil inhibit the MmpS5L5 efflux pump to increase bedaquiline activity.
Adam J Fountain, Natalie J E Waller, Chen-Yi Cheung, William Jowsey, Michael T Chrisp, Gregory M Cook

Proc Natl Acad Sci U S A· April 2025

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Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in Mycobacterium smegmatis.
Gloria Mavinga Bundutidi, Kota Mochizuki, Yuichi Matsuo, Mizuki Hayashishita, Takaya Sakura, Gregory Murray Cook

Commun Biol· February 2025

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Cryo-EM of native membranes reveals an intimate connection between the Krebs cycle and aerobic respiration in mycobacteria.
Justin M Di Trani, Jiacheng Yu, Gautier M Courbon, Ana Paula Lobez Rodriguez, Chen-Yi Cheung, Gregory M Cook

Proc Natl Acad Sci U S A· February 2025

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A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against .
Xirong Tian, Yamin Gao, Chunyu Li, Wanli Ma, Jingran Zhang, Gregory M Cook

Front Pharmacol· January 2025

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Phenotypic-Based Discovery and Exploration of a Resorufin Scaffold with Activity against Mycobacterium tuberculosis.
Eric Tran, Chen-Yi Cheung, Lucy Li, Glen P Carter, Robert W Gable, Gregory M Cook

ChemMedChem· December 2024

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Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis.
XinYue Wang, William J Jowsey, Chen-Yi Cheung, Caitlan J Smart, Hannah R Klaus, Gregory M Cook

Nat Commun· November 2024

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Identification of Chemical Scaffolds That Inhibit the Respiratory Complex Succinate Dehydrogenase.
Cara Adolph, Kiel Hards, Zoe C Williams, Chen-Yi Cheung, Laura M Keighley, Gregory M Cook

ACS Infect Dis· October 2024

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Allenamides as a Powerful Tool to Incorporate Diversity: Thia-Michael Lipidation of Semisynthetic Peptides and Access to β-Keto Amides.
Tae-Ung Na, Veronika Sander, Alan J Davidson, Rolland Lin, Yann O Hermant, Gregory M Cook

Angew Chem Int Ed Engl· September 2024

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Dual transcriptional inhibition of glutamate and alanine racemase is synergistic in .
Matthew B McNeil, Gregory M Cook, Kurt L Krause

Microbiology (Reading)· August 2024

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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus.
Sacha J Pidot, Stephan Klatt, Louis S Ates, Wafa Frigui, Fadel Sayes, Gregory M Cook

PLoS Pathog· August 2024

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Blueprints for ATP machinery will aid tuberculosis drug design.
Gregory M Cook, Matthew B McNeil

Nature· July 2024

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