Publications by authors named "Gregory D McCluskey"

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A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Matthew J McLeod, Norman Tran, Gregory D McCluskey, Tom D Gillis, Stephen L Bearne

Protein Sci· June 2023

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Ancestral acetylcholine receptor β-subunit forms homopentamers that prime before opening spontaneously.
Christian J G Tessier, Raymond M Sturgeon, Johnathon R Emlaw, Gregory D McCluskey, F Javier Pérez-Areales

Elife· July 2022

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A single historical substitution drives an increase in acetylcholine receptor complexity.
Johnathon R Emlaw, Christian J G Tessier, Gregory D McCluskey, Melissa S McNulty, Yusuf Sheikh

Proc Natl Acad Sci U S A· February 2021

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Substrate-product analogue inhibitors of isoleucine 2-epimerase from Lactobacillus buchneri by rational design.
Noa T Sorbara, Joshua W M MacMillan, Gregory D McCluskey, Stephen L Bearne

Org Biomol Chem· September 2019

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"Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage.
Gregory D McCluskey, Stephen L Bearne

Biochim Biophys Acta Gen Subj· December 2018

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Anfractuous assemblies of IMP dehydrogenase and CTP synthase: new twists on regulation?
Gregory D McCluskey, Stephen L Bearne

FEBS J· October 2018

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Biophysical Analysis of Bacterial CTP Synthase Filaments Formed in the Presence of the Chemotherapeutic Metabolite Gemcitabine-5'-triphosphate.
Gregory D McCluskey, Stephen L Bearne

J Mol Biol· April 2018

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Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5'-Triphosphate.
Gregory D McCluskey, Samy Mohamady, Scott D Taylor, Stephen L Bearne

Chembiochem· December 2016

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