Publications by authors named "Gregory Hamilton"

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Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases.
Snahel Patel, Huifen Chen, Eugene Varfolomeev, Youngsu Kwon, Sreemathy Ramaswamy, Gregory L Hamilton

J Med Chem· November 2025

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Acetylation of histone H2B on lysine 120 regulates BRD4 binding to intergenic enhancers.
Gregory A Hamilton, Penelope D Ruiz, Kenny Ye, Matthew J Gamble

bioRxiv· February 2025

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MacroH2A1.1 has evolved to let PARP1 do more by loosening its grip on PAR.
Gregory A Hamilton, Matthew J Gamble

Nat Struct Mol Biol· December 2021

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H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction.
Sean E Healton, Hugo D Pinto, Laxmi N Mishra, Gregory A Hamilton, Justin C Wheat

Proc Natl Acad Sci U S A· June 2020

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Impact of the Canterbury earthquakes on dispensing of psychiatric medication for children and adolescents: longitudinal quantitative study.
Ben Beaglehole, Stephanie Moor, Tao Zhang, Gregory J Hamilton, Roger T Mulder

Br J Psychiatry· March 2020

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MacroH2A1 Regulation of Poly(ADP-Ribose) Synthesis and Stability Prevents Necrosis and Promotes DNA Repair.
Penelope D Ruiz, Gregory A Hamilton, Jong Woo Park, Matthew J Gamble

Mol Cell Biol· December 2019

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Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group.
Gregory L Hamilton, Huifen Chen, Gauri Deshmukh, Charles Eigenbrot, Rina Fong

Bioorg Med Chem Lett· June 2019

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ICare-ACS (Improving Care Processes for Patients With Suspected Acute Coronary Syndrome): A Study of Cross-System Implementation of a National Clinical Pathway.
Martin P Than, John W Pickering, Jeremy M Dryden, Sally J Lord, S Andrew Aitken, Gregory J Hamilton

Circulation· January 2018

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Preface.
Gregory S Hamilton

Cent Nerv Syst Agents Med Chem· January 2018

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Farnesyltransferase-Mediated Delivery of a Covalent Inhibitor Overcomes Alternative Prenylation to Mislocalize K-Ras.
Chris J Novotny, Gregory L Hamilton, Frank McCormick, Kevan M Shokat

ACS Chem Biol· July 2017

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Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice.
Martin P Than, John W Pickering, Sally J Aldous, Louise Cullen, Christopher M A Frampton, Gregory J Hamilton

Ann Emerg Med· July 2016

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Antibody-drug conjugates for cancer therapy: The technological and regulatory challenges of developing drug-biologic hybrids.
Gregory S Hamilton

Biologicals· September 2015

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A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trial.
Martin Than, Sally Aldous, Sarah Jane Lord, Stephen Goodacre, Christopher M A Frampton, Gregory Hamilton

JAMA Intern Med· January 2014

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Uncontrolled hemorrhagic shock results in a hypercoagulable state modulated by initial fluid resuscitation regimens.
Gordon M Riha, Nicholas R Kunio, Philbert Y Van, Igor Kremenevskiy, Ross Anderson, Gregory J Hamilton

J Trauma Acute Care Surg· July 2013

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The pharmaceutical industry. Preface.
Gregory S Hamilton

Cent Nerv Syst Agents Med Chem· March 2013

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The use of lyophilized plasma in a severe multi-injury pig model.
Tim H Lee, Philbert Y Van, Nicholas J Spoerke, Gregory J Hamilton, S David Cho

Transfusion· January 2013

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The progression of chiral anions from concepts to applications in asymmetric catalysis.
Robert J Phipps, Gregory L Hamilton, F Dean Toste

Nat Chem· July 2012

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Editorial.
Gregory S Hamilton, Maria Luz Lopez Rodriguez

Cent Nerv Syst Agents Med Chem· March 2012

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Hextend and 7.5% hypertonic saline with Dextran are equivalent to Lactated Ringer's in a swine model of initial resuscitation of uncontrolled hemorrhagic shock.
Gordon M Riha, Nicholas R Kunio, Philbert Y Van, Gregory J Hamilton, Ross Anderson

J Trauma· December 2011

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Asymmetric electrophilic fluorination using an anionic chiral phase-transfer catalyst.
Vivek Rauniyar, Aaron D Lackner, Gregory L Hamilton, F Dean Toste

Science· December 2011

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Management and outcomes of traumatic colon injury in civilian and military patients.
Chitra N Sambasivan, Samantha J Underwood, Reed B Kuehn, S D Cho, Laszlo N Kiraly, Gregory J Hamilton

Am Surg· December 2011

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Two distinct routes to oral cancer differing in genome instability and risk for cervical node metastasis.
Aditi Bhattacharya, Ritu Roy, Antoine M Snijders, Gregory Hamilton, Jesse Paquette

Clin Cancer Res· November 2011

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Lyophilized plasma with ascorbic acid decreases inflammation in hemorrhagic shock.
Gregory J Hamilton, Philbert Y Van, Jerome A Differding, Igor V Kremenevskiy, Nicholas J Spoerke

J Trauma· August 2011

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Lyophilized plasma reconstituted with ascorbic acid suppresses inflammation and oxidative DNA damage.
Philbert Y Van, Gregory J Hamilton, Igor V Kremenevskiy, Chitra Sambasivan, Nicholas J Spoerke

J Trauma· July 2011

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Advanced hemostatic dressings are not superior to gauze for care under fire scenarios.
Jennifer M Watters, Philbert Y Van, Gregory J Hamilton, Chitra Sambasivan, Jerome A Differding

J Trauma· June 2011

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