Publications by authors named "Gregory Kujoth"

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Endoglucanase 2 (Eng2), a shared immunodominant antigen in dimorphic fungi that elicits immunity during infection.
Uju J Okaa, Cleison Ledesma Taira, Lucas Dos Santos Dias, Hannah Dobson, Gregory C Kujoth

J Clin Invest· November 2025

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Endoglucanase-2 (Eng2), a conserved immunodominant antigen in dimorphic fungi that elicits immunity and resistance during infection.
Uju Joy Okaa, Cleison Ledesma Taira, Lucas Dos Santos Dias, Hannah Dobson, Gregory Kujoth

bioRxiv· June 2025

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Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity.
Lucas Dos Santos Dias, Hannah E Dobson, Brock Kingstad Bakke, Gregory C Kujoth, Junfeng Huang

PLoS Pathog· March 2021

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Gene Editing in Dimorphic Fungi Using CRISPR/Cas9.
Gregory C Kujoth, Thomas D Sullivan, Bruce S Klein

Curr Protoc Microbiol· December 2020

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Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition.
Ryota Kuroki, Yui Murata, Satoshi Fuke, Yutaka Nakachi, Jun Nakashima, Gregory C Kujoth

Front Genet· September 2020

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Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance.
Hannah E Dobson, Lucas Dos Santos Dias, Elaine M Kohn, Scott Fites, Darin L Wiesner, Gregory C Kujoth

Mucosal Immunol· May 2020

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Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.
Darin L Wiesner, Richard M Merkhofer, Carole Ober, Gregory C Kujoth, Mengyao Niu

Cell Host Microbe· April 2020

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Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features.
Jeroen Geurts, Sonia Nasi, Pascal Distel, Magdalena Müller-Gerbl, Tomas A Prolla, Gregory C Kujoth

Sci Rep· January 2020

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CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis.
Gregory C Kujoth, Thomas D Sullivan, Richard Merkhofer, Taek-Jin Lee, Huafeng Wang

mBio· April 2018

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Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice.
Shinichi Someya, Gregory C Kujoth, Mi-Jung Kim, Timothy A Hacker, Marc Vermulst

PLoS One· August 2017

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Monitoring Ischemic Cerebral Injury in Spontaneously Hypertensive Rats by Diffusion Tensor Imaging.
Gregory C Kujoth, Gabriel F Neves, Ulas Cikla, Erinc Akture, Kutluay Uluc

Turk Neurosurg· April 2017

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Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice.
Ying Dai, Joanne Clark, Kangni Zheng, Gregory C Kujoth, Tomas A Prolla

Neurotoxicol Teratol· November 2015

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Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions.
Satoshi Fuke, Mizue Kametani, Kazuyuki Yamada, Takaoki Kasahara, Mie Kubota-Sakashita, Gregory C Kujoth

Ann Clin Transl Neurol· November 2014

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Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease.
Lokesh Kukreja, Gregory C Kujoth, Tomas A Prolla, Fred Van Leuven, Robert Vassar

Mol Neurodegener· May 2014

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Dysregulation of mitochondrial quality control processes contribute to sarcopenia in a mouse model of premature aging.
Anna-Maria Joseph, Peter J Adhihetty, Nicholas R Wawrzyniak, Stephanie E Wohlgemuth, Anna Picca, Gregory C Kujoth

PLoS One· March 2014

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A stepwise illustration of the retrosigmoid approach for resection of a cerebellopontine meningioma.
Ulaş Cıkla, Gregory C Kujoth, Mustafa K Başkaya

Neurosurg Focus· January 2014

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Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice.
Ying Dai, Tomas Kiselak, Joanne Clark, Elizabeth Clore, Kangni Zheng, Gregory C Kujoth

Mitochondrion· July 2013

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Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption.
Raymond G Fox, Scott Magness, Gregory C Kujoth, Tomas A Prolla, Nobuyo Maeda

Am J Physiol Gastrointest Liver Physiol· May 2012

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Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
Raymond Fox, Hyung-Suk Kim, Robert L Reddick, Gregory C Kujoth, Tomas A Prolla

Proc Natl Acad Sci U S A· May 2011

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Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice.
Adeel Safdar, Jacqueline M Bourgeois, Daniel I Ogborn, Jonathan P Little, Bart P Hettinga, Gregory C Kujoth

Proc Natl Acad Sci U S A· March 2011

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Focal cerebral ischemia model by endovascular suture occlusion of the middle cerebral artery in the rat.
Kutluay Uluç, Amrendra Miranpuri, Gregory C Kujoth, Erinç Aktüre, Mustafa K Başkaya

J Vis Exp· February 2011

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Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.
Asimina Hiona, Alberto Sanz, Gregory C Kujoth, Reinald Pamplona, Arnold Y Seo

PLoS One· July 2010

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Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction.
Michael L Chen, T Daniel Logan, Maryann L Hochberg, Suresh G Shelat, Xiang Yu, Gregory C Kujoth

Blood· November 2009

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Operating microscopes: past, present, and future.
Kutluay Uluç, Gregory C Kujoth, Mustafa K Başkaya

Neurosurg Focus· September 2009

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DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.
Marc Vermulst, Jonathan Wanagat, Gregory C Kujoth, Jason H Bielas, Peter S Rabinovitch

Nat Genet· April 2008

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