Publications by authors named "Guan Ning Lin"

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Predicting the regulatory impacts of noncoding variants on gene expression through epigenomic integration across tissues and single-cell landscapes.
Zhe Liu, Yihang Bao, An Gu, Weichen Song, Guan Ning Lin

Nat Comput Sci· October 2025

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MEMO-Stab2: Multi-View Sequence-Based Deep Learning Framework for Predicting Mutation-Induced Stability Changes in Transmembrane Proteins.
Yihang Bao, Zhe Liu, Hui Jin, Han Wang, Weidi Wang, Guan Ning Lin

J Chem Inf Model· October 2025

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Multi-omic dissection of clinically diagnosed and self-reported major depressive disorder reveals phenotype-specific genetic and proteomic architecture in East Asian populations.
Weidi Wang, Xuechen Wang, Miaohan Deng, Yueyang Li, Lei Ding, Guan Ning Lin

Asian J Psychiatr· September 2025

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Enhancing Automated Seizure Detection via Self-Calibrating Spatial-Temporal EEG Features with SC-LSTM.
Wenhao Li, Qiran Chen, Zhenyu Hou, Shi Chang, Zhenhong Ye, Guan Ning Lin

IEEE J Biomed Health Inform· September 2025

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Epigenetic Impacts of Non-Coding Mutations Deciphered Through Pre-Trained DNA Language Model at Single-Cell Resolution.
Zhe Liu, An Gu, Yihang Bao, Guan Ning Lin

Adv Sci (Weinh)· March 2025

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Leveraging deep neural network and language models for predicting long-term hospitalization risk in schizophrenia.
Yihang Bao, Wanying Wang, Zhe Liu, Weidi Wang, Xue Zhao, Guan Ning Lin

Schizophrenia (Heidelb)· March 2025

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Peripheral molecular and brain structural profile implicated stress activation and hyperoxidation in methamphetamine use disorder.
Hang Su, Weichen Song, Qiming Lv, Tianzhen Chen, Xiaotong Li, Guan Ning Lin

Psychiatry Clin Neurosci· February 2025

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Genomic insights into genes expressed specifically during infancy highlight their dominant influence on the neuronal system.
Weidi Wang, Zhe Liu, Daihui Peng, Guan Ning Lin, Zhen Wang

BMC Genomics· October 2024

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Causality Investigation between Gut Microbiome and Sleep-Related Traits: A Bidirectional Two-Sample Mendelian Randomization Study.
Mingxia Zhai, Weichen Song, Zhe Liu, Wenxiang Cai, Guan Ning Lin

Genes (Basel)· June 2024

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Interaction between RNF4 and SART3 is associated with the risk of schizophrenia.
Ying Cheng, Xi Chen, Xiao Qing Zhang, Pei Jun Ju, Wei Di Wang, Guan Ning Lin

Heliyon· June 2024

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Human lineage mutations regulate RNA-protein binding of conserved genes and involved in human evolution.
Wenxiang Cai, Weichen Song, Shunying Yu, Min Zhao, Guan Ning Lin

Gen Psychiatr· May 2024

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Haplotype function score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits.
Weichen Song, Yongyong Shi, Guan Ning Lin

Elife· April 2024

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Emden: A novel method integrating graph and transformer representations for predicting the effect of mutations on clinical drug response.
Zhe Liu, Yihang Bao, Weidi Wang, Liangwei Pan, Han Wang, Guan Ning Lin

Comput Biol Med· December 2023

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Rhesus monkeys exhibiting spontaneous ritualistic behaviors resembling obsessive-compulsive disorder.
Rongwei Zhai, Geya Tong, Zheqin Li, Weichen Song, Yang Hu, Guan Ning Lin

Natl Sci Rev· November 2023

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Inferring the Effects of Protein Variants on Protein-Protein Interactions with Interpretable Transformer Representations.
Zhe Liu, Wei Qian, Wenxiang Cai, Weichen Song, Weidi Wang, Guan Ning Lin

Research (Wash D C)· September 2023

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Author Correction: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen

Nat Commun· February 2023

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Locus-level antagonistic selection shaped the polygenic architecture of human complex diseases.
Weichen Song, Kai Yuan, Zhe Liu, Wenxiang Cai, Jue Chen, Guan Ning Lin

Hum Genet· December 2022

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A Comprehensive Study of De Novo Mutations on the Protein-Protein Interaction Interfaces Provides New Insights into Developmental Delay.
Dhruba Tara Maharjan, Weichen Song, Zhe Liu, Weidi Wang, Wenxiang Cai, Guan Ning Lin

Biomolecules· November 2022

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Evaluation of the Effectiveness of Derived Features of AlphaFold2 on Single-Sequence Protein Binding Site Prediction.
Zhe Liu, Weihao Pan, Weihao Li, Xuyang Zhen, Jisheng Liang, Guan Ning Lin

Biology (Basel)· October 2022

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Mendelian Randomization and GWAS Meta Analysis Revealed the Risk-Increasing Effect of Schizophrenia on Cancers.
Kai Yuan, Weichen Song, Zhe Liu, Guan Ning Lin, Shunying Yu

Biology (Basel)· September 2022

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An Integrative Analysis of Identified Schizophrenia-Associated Brain Cell Types and Gene Expression Changes.
Wenxiang Cai, Weichen Song, Zhe Liu, Dhruba Tara Maharjan, Jisheng Liang, Guan Ning Lin

Int J Mol Sci· September 2022

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Peripheral transcriptome of clinical high-risk psychosis reflects symptom alteration and helps prognosis prediction.
Weichen Song, Lihua Xu, Tianhong Zhang, Weidi Wang, Yingmei Fu, Ailing Ning, Guan Ning Lin

Psychiatry Clin Neurosci· June 2022

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Genome-wide identification of the shared genetic basis of cannabis and cigarette smoking and schizophrenia implicates NCAM1 and neuronal abnormality.
Weichen Song, Guan Ning Lin, Shunying Yu, Min Zhao

Psychiatry Res· April 2022

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An Integrative Segmentation Framework for Cell Nucleus of Fluorescence Microscopy.
Weihao Pan, Zhe Liu, Weichen Song, Xuyang Zhen, Kai Yuan, Guan Ning Lin

Genes (Basel)· February 2022

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De novo mutations identified by whole-genome sequencing implicate chromatin modifications in obsessive-compulsive disorder.
Guan Ning Lin, Weichen Song, Weidi Wang, Pei Wang, Huan Yu

Sci Adv· January 2022

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