Publications by authors named "Guang Bo Ge"

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Discovery of baicalein derivatives as novel covalent inhibitors of SARS CoV-2 M: Structure-activity relationships and inhibitory mechanisms.
Zhao-Qin Zhang, Guang-Hao Zhu, Rong Zhu, Jing-Xuan Lei, Shu-Yan Liu, Guang-Bo Ge

Bioorg Chem· July 2025

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Qing-Fei-Pai-Du-Tang ameliorates lipopolysaccharide-induced rat acute lung injury through attenuating pulmonary microcirculatory disturbances via multi-target regulation.
Shu-Ya He, Chun-Shui Pan, Li Yan, Ping Huang, Lu-Lu Yan, Guang-Bo Ge

Phytomedicine· July 2025

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[Research progress in pharmacological activities and pharmacokinetics of geniposidic acid].
Zi-Wei Li, Sheng-Lan Qi, Qing-Guang Zhang, Ling Chen, Jing Hu, Guang-Bo Ge

Zhongguo Zhong Yao Za Zhi· July 2025

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A patent review of CYP3A4 inhibitors (2018 - present).
Dong-Zhu Tu, Xue-Yan Hu, Jing-Xuan Lei, Shu-Yan Liu, Zhang-Ping Xiao, Guang-Bo Ge

Expert Opin Ther Pat· May 2025

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Uncovering the naturally occurring covalent inhibitors of SARS-CoV-2 M from the Chinese medicine sappanwood and deciphering their synergistic anti-M effects.
Qing Hu, Yi-Wen Zhang, Ya-Ni Zhang, Guang-Hao Zhu, Peng-Cheng Chen, Guang-Bo Ge

J Ethnopharmacol· February 2025

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The study of halogen effect on the reactivity of the serine-targeting covalent warheads.
Conghao Gai, Ya Zhang, Shihao Zhang, Xueyan Hu, Yun-Qing Song, Guang-Bo Ge

Front Chem· December 2024

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Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent -Inhibitor Against Gut Microbial Bile Salt Hydrolases.
Xue-Zhang, Chun-Yu Li, Guang-Hao Zhu, Li-Lin Song, Yi-Wen Zhao, Guang-Bo Ge

J Agric Food Chem· October 2024

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ERRATUM: Cytokine Storm in Acute Viral Respiratory Injury: Role of Qing-Fei-Pai-Du Decoction in Inhibiting the Infiltration of Neutrophils and Macrophages through TAK1/IKK/NF-κB Pathway.
Xiao-Lan Ye, Sai-Sai Tian, Chen-Chen Tang, Xin-Ru Jiang, Dan Liu, Guang-Bo Ge

Am J Chin Med· September 2024

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Discovery of baicalein derivatives as novel inhibitors against human pancreatic lipase: Structure-activity relationships and inhibitory mechanisms.
Xiao-Ya Qin, Rong Zhu, Xu-Dong Hou, Guang-Hao Zhu, Min Zhang, Guang-Bo Ge

Int J Biol Macromol· August 2024

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Human UDP-glucuronosyltransferase 1As catalyze aristolochic acid D O-glucuronidation to form a lesser nephrotoxic glucuronide.
Dong-Zhu Tu, Pei-Qi Liu, Guang-Hao Zhu, Hai-Rong Zeng, Yan-Yan Deng, Guang-Bo Ge

J Ethnopharmacol· June 2024

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Discovery of a botanical compound as a broad-spectrum inhibitor against gut microbial β-glucuronidases from the Tibetan medicine Rhodiola crenulata.
Lu Chen, Xu-Dong Hou, Guang-Hao Zhu, Jian Huang, Zhao-Bin Guo, Guang-Bo Ge

Int J Biol Macromol· May 2024

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Uncovering the anti-obesity constituents in Ginkgo biloba extract and deciphering their synergistic effects.
Min Zhang, Xu-Dong Hou, Wei Liu, Lu Wang, Mei-Fang Jiang, Guang-Bo Ge

Fitoterapia· December 2023

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Human Carboxylesterase 1A Plays a Predominant Role in Hydrolysis of the Anti-Dyslipidemia Agent Fenofibrate in Humans.
Hong-Xin Li, Meng-Ru Sun, Ya Zhang, Li-Lin Song, Feng Zhang, Guang-Bo Ge

Drug Metab Dispos· November 2023

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Discovery of the covalent SARS-CoV-2 M inhibitors from antiviral herbs via integrating target-based high-throughput screening and chemoproteomic approaches.
Ya-Ni Zhang, Guang-Hao Zhu, Wei Liu, Xi-Xiang Chen, Yuan-Yuan Xie, Guang-Bo Ge

J Med Virol· November 2023

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Discovery of 4'-trifluoromethylchalcones as novel, potent and selective hCYP1B1 inhibitors without concomitant AhR activation.
Yue Wu, Jin-Hui Shi, Guang-Hao Zhu, Yuan Xiong, Jia-Hao Gong, Guang-Bo Ge

Eur J Med Chem· October 2023

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Cytokine Storm in Acute Viral Respiratory Injury: Role of Qing-Fei-Pai-Du Decoction in Inhibiting the Infiltration of Neutrophils and Macrophages through TAK1/IKK/NF-[Formula: see text]B Pathway.
Xiao-Lan Ye, Sai-Sai Tian, Chen-Chen Tang, Xin-Ru Jiang, Dan Liu, Guang-Bo Ge

Am J Chin Med· October 2023

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Air-ventilated normothermic machine perfusion alleviates hepatic injury from DCD rat through CYP1A2.
Ji-Hua Shi, Nuo Cheng, Wen Zhang, Qiang Jin, Wen-Zhi Guo, Guang-Bo Ge

Heliyon· August 2023

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Licochalcone A Derivatives as Selective Dipeptidyl Peptidase 4 Inhibitors with Anti-Inflammatory Effects.
Ci-Qin Li, Jin-Hui Shi, Jie Mu, An-Qi Wang, Li-Wei Zou, Guang-Bo Ge

J Nat Prod· July 2023

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Protective effects and regulatory mechanisms of Shen-shuai-yi recipe on renal fibrosis in unilateral ureteral obstruction-induced mice.
Ping-Lan Lin, Tao-Tao Weng, Lian-Xiang Duan, Lin-Zhang Zhang, Xia Wei, Guang-Bo Ge

Heliyon· July 2023

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Discovery and characterization of the covalent SARS-CoV-2 3CL inhibitors from Ginkgo biloba extract via integrating chemoproteomic and biochemical approaches.
Ya-Ni Zhang, Guang-Hao Zhu, Wei Liu, Yuan Xiong, Qing Hu, Guang-Bo Ge

Phytomedicine· June 2023

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A rationally engineered specific near-infrared fluorogenic substrate of human pancreatic lipase for functional imaging and inhibitor screening.
Fan-Bin Hou, Na Zhang, Xu-Dong Hou, Wei Liu, Yu-Fan Fan, Guang-Bo Ge

Analyst· May 2023

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Rationally Engineered CYP3A4 Fluorogenic Substrates for Functional Imaging Analysis and Drug-Drug Interaction Studies.
Rong-Jing He, Zhen-Hao Tian, Jian Huang, Meng-Ru Sun, Feng Wei, Guang-Bo Ge

J Med Chem· May 2023

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Enzyme-Based Biosensors and Their Applications.
Yu-Fan Fan, Zhao-Bin Guo, Guang-Bo Ge

Biosensors (Basel)· April 2023

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[Strategy and challenge of innovative drug research and development from clinically effective ingredients of traditional Chinese medicine].
Xin Luan, Min Huang, Bo-Wen Ke, Guang-Bo Ge, Wei-Dong Zhang

Zhongguo Zhong Yao Za Zhi· April 2023

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Synthesis and biological evaluation of esculetin derivatives as potential anti-HBV agents.
Zhen Ye, Tong-Shi-Yao Zhao, Shan-Bin Li, Xian-Li Zhou, Qin Luo, Guang-Bo Ge

Med Chem Res· March 2023

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