Publications by authors named "Guanghao Qi"

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Transcriptome-wide association studies at cell-state level using single-cell eQTL data.
Guanghao Qi, Eardi Lila, Zhicheng Ji, Ali Shojaie, Alexis Battle

Cell Genom· November 2025

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DAESC+: High-performance, integrated software for single-cell allele-specific expression data.
Tengfei Cui, Guanghao Qi

bioRxiv· September 2025

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Transcriptome-wide association studies at cell state level using single-cell eQTL data.
Guanghao Qi, Eardi Lila, Zhicheng Ji, Ali Shojaie, Alexis Battle

medRxiv· March 2025

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Computational methods for allele-specific expression in single cells.
Guanghao Qi, Alexis Battle

Trends Genet· November 2024

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Mendelian randomization analysis using multiple biomarkers of an underlying common exposure.
Jin Jin, Guanghao Qi, Zhi Yu, Nilanjan Chatterjee

Biostatistics· October 2024

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Genome-wide large-scale multi-trait analysis characterizes global patterns of pleiotropy and unique trait-specific variants.
Guanghao Qi, Surya B Chhetri, Debashree Ray, Diptavo Dutta, Alexis Battle

Nat Commun· August 2024

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SURGE: uncovering context-specific genetic-regulation of gene expression from single-cell RNA sequencing using latent-factor models.
Benjamin J Strober, Karl Tayeb, Joshua Popp, Guanghao Qi, M Grace Gordon

Genome Biol· January 2024

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Single-cell allele-specific expression analysis reveals dynamic and cell-type-specific regulatory effects.
Guanghao Qi, Benjamin J Strober, Joshua M Popp, Rebecca Keener, Hongkai Ji

Nat Commun· October 2023

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Genome-wide association studies of 27 accelerometry-derived physical activity measurements identified novel loci and genetic mechanisms.
Guanghao Qi, Diptavo Dutta, Andrew Leroux, Debashree Ray, John Muschelli

Genet Epidemiol· March 2022

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Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation.
Reem Elorbany, Joshua M Popp, Katherine Rhodes, Benjamin J Strober, Kenneth Barr, Guanghao Qi

PLoS Genet· January 2022

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A comprehensive evaluation of methods for Mendelian randomization using realistic simulations and an analysis of 38 biomarkers for risk of type 2 diabetes.
Guanghao Qi, Nilanjan Chatterjee

Int J Epidemiol· August 2021

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Linear and Nonlinear Mendelian Randomization Analyses of the Association Between Diastolic Blood Pressure and Cardiovascular Events: The J-Curve Revisited.
Marios Arvanitis, Guanghao Qi, Deepak L Bhatt, Wendy S Post, Nilanjan Chatterjee

Circulation· March 2021

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A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure.
Zhi Yu, Josef Coresh, Guanghao Qi, Morgan Grams, Eric Boerwinkle

Kidney Int· September 2020

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Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.
Haoyu Zhang, Thomas U Ahearn, Julie Lecarpentier, Daniel Barnes, Jonathan Beesley, Guanghao Qi, Qin Wang

Nat Genet· June 2020

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Mendelian randomization analysis using mixture models for robust and efficient estimation of causal effects.
Guanghao Qi, Nilanjan Chatterjee

Nat Commun· April 2019

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Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.
Guanghao Qi, Nilanjan Chatterjee

PLoS Genet· October 2018

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Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits.
Yan Zhang, Guanghao Qi, Ju-Hyun Park, Nilanjan Chatterjee

Nat Genet· September 2018

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