Publications by authors named "Guanglan Wu"

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RNA-DNA hybrid binding domain broadens the editing window of base editors.
Yue Yang, Zihao Fu, Shengcheng Deng, Guanglan Wu, Chuanle Wang

Mol Ther· September 2025

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Rationally designed Cas9 enables efficient gene activation and base editing.
Yuxi Chen, Rui Kang, Yuanling Jiang, Qi Zheng, Yue Yang, Guanglan Wu, Guifang Wu

Mol Ther Nucleic Acids· December 2024

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Correction of a CADASIL point mutation using adenine base editors in hiPSCs and blood vessel organoids.
Jingwen Wang, Lei Zhang, Guanglan Wu, Jinni Wu, Xinyao Zhou, Xueqing Wu

J Genet Genomics· February 2024

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Identification and Analysis of Small Molecule Inhibitors of CRISPR-Cas9 in Human Cells.
Yue Yang, Donghua Li, Fen Wan, Bohong Chen, Guanglan Wu

Cells· November 2022

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Single AAV-mediated CRISPR-Nme2Cas9 efficiently reduces mutant hTTR expression in a transgenic mouse model of transthyretin amyloidosis.
Jinkun Wen, Tianqi Cao, Jinni Wu, Yuxi Chen, Shengyao Zhi, Guanglan Wu

Mol Ther· January 2022

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Dual-AAV delivering split prime editor system for in vivo genome editing.
Shengyao Zhi, Yuxi Chen, Guanglan Wu, Jinkun Wen, Jinni Wu

Mol Ther· January 2022

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Cost-effective generation of A-to-G mutant mice by zygote electroporation of adenine base editor ribonucleoproteins.
Hongwei Sun, Shengyao Zhi, Guifang Wu, Guanglan Wu, Tianqi Cao

J Genet Genomics· June 2020

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