Publications by authors named "Guanzhen Yu"

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Chinese expert opinion on AI-based identification of lymph node metastases in solid tumors.
Xiaodong Wang, Hong Tang, Ying Chen, Xiaolin Zhang, Xiyang Liu, Guanzhen Yu

J Histotechnol· December 2025

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Xylulose 5-phosphate fosters sustained antitumor activity of progenitor-like exhausted SLC35E2 CD8 T effector cells.
Tiezhu Shi, Jialiang Shao, Yufeng Ding, Hong Tang, Xiangyin Tan, Shaoqing Yu, Guanzhen Yu

Cell Metab· September 2025

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Spatial transcriptomic analysis of 4NQO-induced tongue cancer revealed cellular lineage diversity and evolutionary trajectory.
Feng Liu, Xiaojun Wu, Shaoqing Yu, Deqiang Cheng, Jun Pan, Guanzhen Yu

Front Oncol· July 2025

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Automatic segmentation of clear cell renal cell carcinoma based on deep learning and a preliminary exploration of the tumor microenvironment.
Hong Tang, Haibin Zhao, Shaoqing Yu, Yang Wang, Jinzhu Su, Guanzhen Yu

Transl Androl Urol· July 2025

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Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways.
Qijie Chen, Shaoqing Yu, Yating Pan, Hong Tang, Yang Wang, Guanzhen Yu

Transl Androl Urol· June 2025

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Neoplasms in the Nasal Cavity Identified and Tracked with an Artificial Intelligence-Assisted Nasal Endoscopic Diagnostic System.
Xiayue Xu, Boxiang Yun, Yumin Zhao, Ling Jin, Yanning Zong, Guanzhen Yu, Shaoqing Yu

Bioengineering (Basel)· December 2024

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An analysis on efficacy of applying β-elemene intervention on chemically -induced tongue lesions using SAM algorithm.
Feng Liu, Qinlong Zhang, Weijie Zhang, Deqiang Cheng, Feng Zhang, Guanzhen Yu

Anat Histol Embryol· September 2024

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Metformin dampens the progression of cholangiofibrosis induced by thioacetamide using deep learning.
Chaofu Li, Yating Deng, Yating Pan, Xinyi Liao, Huadong Xie, Shaoqing Yu, Wenlong Yu, Guanzhen Yu

Heliyon· September 2024

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Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma.
Xing Jin, Lei Liu, Dan Liu, Jia Wu, Congcong Wang, Guanzhen Yu, Yu-Wen Xue, Yuriy L Orlov

Cell Death Differ· May 2024

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Nuclear translocation of cleaved PCDH9 impairs gastric cancer metastasis by downregulating CDH2 expression.
Yajuan Zhang, Yingwei Zhu, Ying Chen, Yanli Wang, Bing Liu, Guanzhen Yu

iScience· February 2024

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Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Dan Liu, Changsheng Dong, Fengying Wang, Wei Liu, Xing Jin, Yuejiao Cai, Guanzhen Yu, Yu-Wen Xue

Phytomedicine· May 2023

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PI3K/ c-Myc/AFF4 axis promotes pancreatic tumorigenesis through fueling nucleotide metabolism.
Chenming Ni, Wenyu Liu, Kailian Zheng, Shiwei Guo, Bin Song, Guanzhen Yu

Int J Biol Sci· April 2023

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Piperine alleviates acute pancreatitis: A possible role for FAM134B and CCPG1 dependent ER-phagy.
Weiguo Huang, Jie Zhang, Wenzhang Jin, Jintao Yang, Guanzhen Yu

Phytomedicine· October 2022

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New Metabolic Alterations and A Predictive Marker Pipecolic Acid in Sera for Esophageal Squamous Cell Carcinoma.
Lei Liu, Jia Wu, Minxin Shi, Fengying Wang, Haimin Lu, Guanzhen Yu

Genomics Proteomics Bioinformatics· August 2022

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The Chemopreventive Role of β-Elemene in Cholangiocarcinoma by Restoring Expression.
Qing Wu, Xintong Shi, Yating Pan, Xinyi Liao, Jiahua Xu, Wenlong Yu, Guanzhen Yu

Front Oncol· July 2022

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Extract of (Roxb.) Moon [Apocynaceae] Suppresses Hepatocellular Carcinoma by Inhibiting Angiogenesis.
Yating Pan, Xinyi Liao, Lili Yang, Chunlei Zhang, Jue Wang, Guanzhen Yu

Front Pharmacol· June 2022

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MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion.
Yajuan Zhang, Ming Zhao, Hong Gao, Guanzhen Yu, Yun Zhao

Nat Metab· March 2022

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Oleanolic acid blocks the purine salvage pathway for cancer therapy by inactivating SOD1 and stimulating lysosomal proteolysis.
Dan Liu, Xing Jin, Guanzhen Yu, Mingsong Wang, Lei Liu

Mol Ther Oncolytics· December 2021

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[Hydrogen-rich water improves progressive sperm motility in rats by reducing oxidative stress and upregulating CLDN3 and SRD5A2 expressions].
Hong Tang, Guan-Zhen Yu, Chao-Fu Li, Yang Wang, Guo-Tao Chen

Zhonghua Nan Ke Xue· December 2021

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Accurate prediction of acute pancreatitis severity based on genome-wide cell free DNA methylation profiles.
Hong-Wei Sun, Sheng-Jie Dai, Hong-Ru Kong, Jie-Xiang Fan, Fang-Yuan Yang, Yue-Peng Jin, Guan-Zhen Yu

Clin Epigenetics· December 2021

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Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine.
Yajuan Zhang, Hua Yu, Jie Zhang, Hong Gao, Siyao Wang, Guanzhen Yu

J Clin Invest· November 2021

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Diagnostic assessment of deep learning for melanocytic lesions using whole-slide pathological images.
Wei Ba, Rui Wang, Guang Yin, Zhigang Song, Jinyi Zou, Guanzhen Yu, Hongyu Yang

Transl Oncol· September 2021

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A multi-omics study delineates new molecular features and therapeutic targets for esophageal squamous cell carcinoma.
Xing Jin, Lei Liu, Jia Wu, Xiaoxia Jin, Guanzhen Yu

Clin Transl Med· September 2021

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The Preventive Role of Hydrogen-Rich Water in Thioacetamide-Induced Cholangiofibrosis in Rat Assessed by Automated Histological Classification.
Chaofu Li, Xing Zhao, Xiaoqiang Gu, Ying Chen, Guanzhen Yu

Front Pharmacol· August 2021

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S100 Calcium Binding Protein A10, A Novel Oncogene, Promotes the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma.
Xing Zhou, Min Shi, Jun Cao, Tianwen Yuan, Guanzhen Yu

Front Genet· June 2021

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