Publications by authors named "Guido Hansen"

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A critical residue in a conserved RBD epitope determines neutralization breadth of pan-sarbecovirus antibodies with recurring YYDRxxG motifs.
Saskia C Stein, George Ssebyatika, Tim Benecke, Luisa Ströh, Manoj K Rajak, Guido Hansen

mBio· September 2025

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evolution of ceftazidime-avibactam resistance in -positive potentially linked to PBP3 insertion and mutations in and PBP2.
Kaan Kocer, Sébastien Boutin, Guido Hansen, Dennis Nurjadi, Niklas Maximilian Weidner

JAC Antimicrob Resist· August 2025

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A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation.
Saskia C Stein, Guido Hansen, George Ssebyatika, Luisa J Ströh, Okechukwu Ochulor

J Virol· December 2024

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Inhibitory effect of sorangicin A against mutant DNA-dependent RNA polymerase in the obligate intracellular bacterium Chlamydia trachomatis.
Qiang Li, Hendrik Jansen, Guido Hansen, Dennis Nurjadi, Jennifer Herrmann

Int J Antimicrob Agents· May 2024

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Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2 Variants of Concern.
Ivan Odak, Christian R Schultze-Florey, Swantje I Hammerschmidt, Christiane Ritter, Stefanie Willenzon, Guido Hansen

Front Immunol· April 2022

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Association of body surface scanner-based abdominal volume with parameters of the Metabolic Syndrome and comparison with manually measured waist circumference.
Lina Jaeschke, Astrid Steinbrecher, Guido Hansen, Stefan Sommer, Carolin Adler

Sci Rep· June 2020

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Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins.
Sebastian Pomplun, Claudia Sippel, Andreas Hähle, Donald Tay, Kensuke Shima, Guido Hansen

J Med Chem· April 2018

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Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor.
Jian Lei, Guido Hansen, Christoph Nitsche, Christian D Klein, Linlin Zhang

Science· July 2016

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Production, crystallization and X-ray diffraction analysis of the protease CT441 from Chlamydia trachomatis.
Friedrich Kohlmann, Kensuke Shima, Jan Rupp, Werner Solbach, Rolf Hilgenfeld, Guido Hansen

Acta Crystallogr F Struct Biol Commun· December 2015

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Structures of DegQ from Legionella pneumophila Define Distinct ON and OFF States.
Alexander Schubert, Robert Wrase, Rolf Hilgenfeld, Guido Hansen

J Mol Biol· August 2015

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Structural basis of the proteolytic and chaperone activity of Chlamydia trachomatis CT441.
Friedrich Kohlmann, Kensuke Shima, Rolf Hilgenfeld, Werner Solbach, Jan Rupp, Guido Hansen

J Bacteriol· January 2015

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Fungal effector Ecp6 outcompetes host immune receptor for chitin binding through intrachain LysM dimerization.
Andrea Sánchez-Vallet, Raspudin Saleem-Batcha, Anja Kombrink, Guido Hansen, Dirk-Jan Valkenburg

Elife· July 2013

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Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response.
Guido Hansen, Rolf Hilgenfeld

Cell Mol Life Sci· March 2013

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Structural and mechanistic analysis of the membrane-embedded glycosyltransferase WaaA required for lipopolysaccharide synthesis.
Helgo Schmidt, Guido Hansen, Sonia Singh, Anna Hanuszkiewicz, Buko Lindner

Proc Natl Acad Sci U S A· April 2012

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The macromolecular complex of ICP and falcipain-2 from Plasmodium: preparation, crystallization and preliminary X-ray diffraction analysis.
Guido Hansen, Britta Schwarzloh, Annika Rennenberg, Volker T Heussler, Rolf Hilgenfeld

Acta Crystallogr Sect F Struct Biol Cryst Commun· November 2011

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Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
Guido Hansen, Anna Heitmann, Tina Witt, Honglin Li, Hualiang Jiang

Structure· July 2011

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Crystal structure of the Leishmania major MIX protein: a scaffold protein that mediates protein-protein interactions.
Michael A Gorman, Alex D Uboldi, Peter J Walsh, Kher Shing Tan, Guido Hansen

Protein Sci· June 2011

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Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
Guido Hansen, Heike Gielen-Haertwig, Peter Reinemer, Dietmar Schomburg, Axel Harrenga

J Mol Biol· June 2011

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The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies.
Robert Wrase, Hannah Scott, Rolf Hilgenfeld, Guido Hansen

Proc Natl Acad Sci U S A· June 2011

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ppGpp analogues inhibit synthetase activity of Rel proteins from Gram-negative and Gram-positive bacteria.
Ezequiel Wexselblatt, Jehoshua Katzhendler, Raspudin Saleem-Batcha, Guido Hansen, Rolf Hilgenfeld

Bioorg Med Chem· June 2010

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Exoerythrocytic Plasmodium parasites secrete a cysteine protease inhibitor involved in sporozoite invasion and capable of blocking cell death of host hepatocytes.
Annika Rennenberg, Christine Lehmann, Anna Heitmann, Tina Witt, Guido Hansen

PLoS Pathog· March 2010

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Structure of the GTPase and GDI domains of FeoB, the ferrous iron transporter of Legionella pneumophila.
Nele Petermann, Guido Hansen, Christian L Schmidt, Rolf Hilgenfeld

FEBS Lett· February 2010

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Crystallization and preliminary X-ray analysis of glutathione transferases from cyanobacteria.
Susanne C Feil, Julian Tang, Guido Hansen, Michael A Gorman, Eric Wiktelius

Acta Crystallogr Sect F Struct Biol Cryst Commun· May 2009

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The SARS-unique domain (SUD) of SARS coronavirus contains two macrodomains that bind G-quadruplexes.
Jinzhi Tan, Clemens Vonrhein, Oliver S Smart, Gerard Bricogne, Michela Bollati, Guido Hansen

PLoS Pathog· May 2009

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Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property.
Yvonne Piotrowski, Guido Hansen, A Linda Boomaars-van der Zanden, Eric J Snijder, Alexander E Gorbalenya

Protein Sci· January 2009

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