Publications by authors named "Guixiong Fan"

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Tumor-derived apolipoprotein E confers resistance to temozolomide in pancreatic neuroendocrine tumors.
Xin Lou, Yihua Shi, Yi Qin, Wuhu Zhang, Zeng Ye, Guixiong Fan

Cell Death Dis· December 2025

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ACSS2/AATF Drives Soluble FasL-Mediated CD8 T Cell Apoptosis in Pancreatic Neuroendocrine Tumors.
Qin Dang, Ting Wang, Yan Wang, Zeng Ye, Borui Li, Guixiong Fan

Adv Sci (Weinh)· October 2025

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Small extracellular vesicle-miR-183-5p mediated crosstalk between tumor cells and macrophages in high-risk pancreatic neuroendocrine tumors.
Wuhu Zhang, Junfeng Xu, Dan Huang, Yi Qin, Xin Lou, Guixiong Fan

Oncogene· August 2025

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Pancreatic Neuroendocrine Tumors Secrete Apolipoprotein E to Induce Tip Endothelial Cells That Remodel the Tumor-Stroma Ratio and Promote Cancer Progression.
Xin Lou, Yihua Shi, Faming Zhao, Xiaowu Xu, Yan Wang, Guixiong Fan

Cancer Res· August 2025

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Acyl-CoA thioesterase 8 induces gemcitabine resistance via regulation of lipid metabolism and antiferroptotic activity in pancreatic ductal adenocarcinoma.
Bo-Rui Li, Ting Wang, Hai-Feng Hu, Di Wu, Chen-Jie Zhou, Gui-Xiong Fan

Acta Pharmacol Sin· June 2025

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Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups.
Shunrong Ji, Lihua Cao, Jing Gao, Yang Du, Zeng Ye, Guixiong Fan

Cancer Cell· April 2025

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knockdown enhances RSL3-induced ferroptosis in pancreatic cancer cells and increases the sensitivity to gemcitabine.
Yuming Jia, Zeng Ye, Xin Wang, Yanli Deng, Chao Wang, Guixiong Fan

Acta Biochim Biophys Sin (Shanghai)· March 2025

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Transcription factor EB reprograms branched-chain amino acid metabolism and promotes pancreatic cancer progression via transcriptional regulation of BCAT1.
Ting Wang, Qiangsheng Hu, Borui Li, Guixiong Fan, Desheng Jing

Cell Prolif· November 2024

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YBX1 as a therapeutic target to suppress the LRP1-β-catenin-RRM1 axis and overcome gemcitabine resistance in pancreatic cancer.
Borui Li, Faliang Xing, Jingyi Wang, Xiaohong Wang, Chenjie Zhou, Guixiong Fan

Cancer Lett· October 2024

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MEN1 Deficiency-Driven Activation of the β-Catenin-MGMT Axis Promotes Pancreatic Neuroendocrine Tumor Growth and Confers Temozolomide Resistance.
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Guixiong Fan

Adv Sci (Weinh)· September 2024

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SMAD4 endows TGF-β1-induced highly invasive tumor cells with ferroptosis vulnerability in pancreatic cancer.
Hai-di Chen, Zeng Ye, Hai-Feng Hu, Gui-Xiong Fan, Yu-Heng Hu

Acta Pharmacol Sin· April 2024

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The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes.
Zeng Ye, Qiang Li, Yuheng Hu, Haifeng Hu, Junfeng Xu, Guixiong Fan

Cancer Lett· April 2024

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Lactate-induced protein lactylation: A bridge between epigenetics and metabolic reprogramming in cancer.
Ting Wang, Zeng Ye, Zheng Li, De-Sheng Jing, Gui-Xiong Fan

Cell Prolif· October 2023

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Nuclear receptor coactivator 6 (NCoA6) promotes cell proliferation, migration, and invasion in pancreatic cancer.
Xin Wang, Yuming Jia, Xiaowu Xu, Yuheng Hu, Guixiong Fan

Cancer Med· September 2023

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A new glance at autophagolysosomal-dependent or -independent function of transcriptional factor EB in human cancer.
Ting Wang, Yi Qin, Zeng Ye, De-Sheng Jing, Gui-Xiong Fan

Acta Pharmacol Sin· August 2023

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MEN1 Degradation Induced by Neddylation and the CUL4B-DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression.
Junfeng Xu, Zeng Ye, Qifeng Zhuo, Heli Gao, Yi Qin, Guixiong Fan

Cancer Res· July 2023

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Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway.
Chang-Feng Song, Yu-Heng Hu, Zhi-Guo Mang, Zeng Ye, Hai-di Chen, Gui-Xiong Fan

Acta Pharmacol Sin· April 2023

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SETD8 inhibits ferroptosis in pancreatic cancer by inhibiting the expression of RRAD.
Zekun Lu, Qiangsheng Hu, Yi Qin, Hao Yang, Bingkai Xiao, Guixiong Fan

Cancer Cell Int· March 2023

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MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors.
Zeng Ye, Haidi Chen, Shunrong Ji, Yuheng Hu, Xin Lou, Guixiong Fan

Acta Biochim Biophys Sin (Shanghai)· November 2022

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Value of lymphadenectomy in patients with surgically resected pancreatic neuroendocrine tumors.
Zheng Zhang, Fei Wang, Zheng Li, Zeng Ye, Qifeng Zhuo, Guixiong Fan

BMC Surg· May 2022

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Pevonedistat Suppresses Pancreatic Cancer Growth Inactivation of the Neddylation Pathway.
Junfeng Xu, Zheng Li, Qifeng Zhuo, Zeng Ye, Guixiong Fan

Front Oncol· January 2022

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SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Mengqi Liu, Yihua Shi, Qiangsheng Hu, Yi Qin, Shunrong Ji, Guixiong Fan

Acta Biochim Biophys Sin (Shanghai)· December 2021

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MTAP Deficiency-Induced Metabolic Reprogramming Creates a Vulnerability to Cotargeting Purine Synthesis and Glycolysis in Pancreatic Cancer.
Qiangsheng Hu, Yi Qin, Shunrong Ji, Xiuhui Shi, Weixing Dai, Guixiong Fan

Cancer Res· October 2021

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ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells.
Haidi Chen, Zeng Ye, Xiaowu Xu, Yi Qin, Changfeng Song, Guixiong Fan

Cancer Cell Int· September 2021

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Improved tumor control with antiangiogenic therapy after treatment with gemcitabine and nab-paclitaxel in pancreatic cancer.
Zheng Zhang, Shunrong Ji, Qiangsheng Hu, Qifeng Zhuo, Wei Liu, Guixiong Fan

Clin Transl Med· August 2021

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