Publications by authors named "Guizhu Hong"

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Emodin facilitates the transformation of A1/A2 reactive astrocytes through the 11β-HSD1/AKT signaling pathway in the context of cerebral ischemia.
Wenfang Lai, Huiling Wu, Yuting Jiang, Xuerui Zheng, Jingquan Chen, Haimian Hong, Guizhu Hong

Int Immunopharmacol· December 2025

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Neuroprotective effects of Rosavin via HIF-1α signaling in a rat model of ischemic stroke.
Wenfang Lai, Jingwen Nie, Anqi Hong, Yan Zhang, Jingquan Chen, Guizhu Hong

Phytomedicine· September 2025

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Salidroside facilitates neuroprotective effects in ischemic stroke by promoting axonal sprouting through promoting autophagy.
Wenfang Lai, Yanfeng He, Binbin Zhou, Qingqing Wu, Huiling Wu, Guizhu Hong

Phytomedicine· December 2024

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Toll-like receptor 4-dependent innate immune responses are mediated by intracrine corticosteroids and activation of glycogen synthase kinase-3β in astrocytes.
Wenfang Lai, Siying Huang, Junjie Liu, Binbin Zhou, Zhengshuang Yu, Guizhu Hong

FASEB J· July 2024

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Salidroside directly activates HSC70, revealing a new role for HSC70 in BDNF signalling and neurogenesis after cerebral ischemia.
Wenfang Lai, Rui Luo, Yuheng Tang, Zhengshuang Yu, Binbin Zhou, Guizhu Hong

Phytother Res· June 2024

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Synthesis and identification of a novel derivative of salidroside as a selective, competitive inhibitor of monoamine oxidase B with enhanced neuroprotective properties.
Zelin Yang, Xin Huang, Wenfang Lai, Yuheng Tang, Junjie Liu, Guizhu Hong

Eur J Med Chem· January 2021

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Inhibition of Complement Drives Increase in Early Growth Response Proteins and Neuroprotection Mediated by Salidroside After Cerebral Ischemia.
Wenfang Lai, XiuLi Xie, Xiaoqin Zhang, Yingzheng Wang, Kedan Chu, Guizhu Hong

Inflammation· March 2018

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Salidroside Inhibits Inflammation Through PI3K/Akt/HIF Signaling After Focal Cerebral Ischemia in Rats.
Yicong Wei, Haimian Hong, Xiaoqin Zhang, Wenfang Lai, Yingzheng Wang, Guizhu Hong

Inflammation· August 2017

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Salidroside-Mediated Neuroprotection is Associated with Induction of Early Growth Response Genes (Egrs) Across a Wide Therapeutic Window.
Wenfang Lai, Zhenwei Zheng, Xiaoqin Zhang, Yicong Wei, Kedan Chu, Guizhu Hong

Neurotox Res· August 2015

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11β-HSD1 modulates LPS-induced innate immune responses in adipocytes by altering expression of PTEN.
Wenfang Lai, Xue Tian, Qing Xiang, Kedan Chu, Yicong Wei, Guizhu Hong

Mol Endocrinol· April 2015

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Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar.
Colin Spraggs, Alun McCarthy, Linda McCarthy, Guizhu Hong, Arlene Hughes

Pharmacogenet Genomics· December 2007

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Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes.
Hassan Rahmoune, Paul W Thompson, Joanna M Ward, Chari D Smith, Guizhu Hong

Diabetes· December 2005

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Delineation of positron emission tomography imaging agent binding sites on beta-amyloid peptide fibrils.
Liang Ye, Jennifer L Morgenstern, Antony D Gee, Guizhu Hong, John Brown

J Biol Chem· June 2005

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Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils.
Andrew Lockhart, Liang Ye, Duncan B Judd, Andy T Merritt, Peter N Lowe, Guizhu Hong

J Biol Chem· March 2005

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PPARgamma activation enhances cell surface ENaCalpha via up-regulation of SGK1 in human collecting duct cells.
Guizhu Hong, Andrew Lockhart, Bill Davis, Hassan Rahmoune, Sharon Baker

FASEB J· October 2003

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PPAR gamma-dependent anti-inflammatory action of rosiglitazone in human monocytes: suppression of TNF alpha secretion is not mediated by PTEN regulation.
Guizhu Hong, Bill Davis, Nachima Khatoon, Sharon F Baker, John Brown

Biochem Biophys Res Commun· April 2003

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The peripheral benzodiazepine receptor ligand PK11195 binds with high affinity to the acute phase reactant alpha1-acid glycoprotein: implications for the use of the ligand as a CNS inflammatory marker.
Andrew Lockhart, Bill Davis, Julian C Matthews, Hassan Rahmoune, Guizhu Hong

Nucl Med Biol· February 2003

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