Publications by authors named "Gulab S Zode"

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Therapeutic mRNA delivery of CRISPR-Cas9 to the trabecular meshwork reverses ocular hypertension in myocilin glaucoma.
Sam Yacoub, Balasankara Reddy Kaipa, Linya Li, Sarahi Rios, Ramesh Kasetti, Gulab S Zode

Mol Ther Methods Clin Dev· December 2025

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Genetic and pharmacological correction of impaired mitophagy in retinal ganglion cells rescues glaucomatous neurodegeneration.
Prabhavathi Maddineni, Bindu Kodati, Balasankara Reddy Kaipa, Karthikeyan Kesavan, J Cameron Millar, Gulab S Zode

bioRxiv· February 2025

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C/EBP Homologous Protein Expression in Retinal Ganglion Cells Induces Neurodegeneration in Mice.
William C Mayhew, Balasankara Reddy Kaipa, Linya Li, Prabhavathi Maddineni, Yogapriya Sundaresan, Gulab S Zode

Int J Mol Sci· February 2025

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Impaired axonal transport contributes to neurodegeneration in a Cre-inducible mouse model of myocilin-associated glaucoma.
Balasankara Reddy Kaipa, Ramesh Kasetti, Yogapriya Sundaresan, Linya Li, Sam Yacoub, Gulab S Zode

JCI Insight· January 2025

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Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches.
Ted S Acott, Michael P Fautsch, Weiming Mao, C Ross Ethier, Alex S Huang, Gulab S Zode

Invest Ophthalmol Vis Sci· December 2024

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Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Shruti V Patil, Balasankara Reddy Kaipa, Sujata Ranshing, Yogapriya Sundaresan, J Cameron Millar, Gulab S Zode

Sci Rep· March 2024

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Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Shruti V Patil, Balasankara Reddy Kaipa, Sujata Ranshing, Yogapriya Sundaresan, J Cameron Millar, Gulab S Zode

Res Sq· December 2023

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Viral Vector-Induced Ocular Hypertension in Mice.
J Cameron Millar, Yogapriya Sundaresan, Gulab S Zode, Abbot F Clark

Methods Mol Biol· August 2023

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A Novel Mouse Model of TGFβ2-Induced Ocular Hypertension Using Lentiviral Gene Delivery.
Shruti V Patil, Ramesh B Kasetti, J Cameron Millar, Gulab S Zode

Int J Mol Sci· June 2022

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Sodium 4-Phenylbutyrate Reduces Ocular Hypertension by Degrading Extracellular Matrix Deposition via Activation of MMP9.
Prabhavathi Maddineni, Ramesh B Kasetti, Bindu Kodati, Sam Yacoub, Gulab S Zode

Int J Mol Sci· September 2021

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Technical brief: Direct, real-time electrochemical measurement of nitric oxide in ex vivo cultured human corneoscleral segments.
Pinkal D Patel, Ramesh B Kasetti, Swapnil K Sonkusare, Gulab S Zode

Mol Vis· May 2021

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Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma.
Pinkal D Patel, Yen-Lin Chen, Ramesh B Kasetti, Prabhavathi Maddineni, William Mayhew, Gulab S Zode

Proc Natl Acad Sci U S A· April 2021

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Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension.
Zdravka Daneva, Corina Marziano, Matteo Ottolini, Yen-Lin Chen, Thomas M Baker, Gulab S Zode

Proc Natl Acad Sci U S A· April 2021

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Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin.
Ramesh B Kasetti, Prabhavathi Maddineni, Charles Kiehlbauch, Shruti Patil, Charles C Searby, Gulab S Zode

JCI Insight· March 2021

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ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load.
Ramesh B Kasetti, Pinkal D Patel, Prabhavathi Maddineni, Shruti Patil, Charles Kiehlbauch, Gulab S Zode

Nat Commun· November 2020

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Mechanisms underlying selective coupling of endothelial Ca signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries.
Matteo Ottolini, Zdravka Daneva, Yen-Lin Chen, Eric L Cope, Ramesh B Kasetti, Gulab S Zode

J Physiol· September 2020

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Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork.
Ramesh B Kasetti, Pinkal D Patel, Prabhavathi Maddineni, Gulab S Zode

PLoS One· August 2020

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Correction: Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork.
Ramesh B Kasetti, Pinkal D Patel, Prabhavathi Maddineni, Gulab S Zode

PLoS One· August 2020

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CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma.
Prabhavathi Maddineni, Ramesh B Kasetti, Pinkal D Patel, J Cameron Millar, Charles Kiehlbauch, Gulab S Zode

Mol Neurodegener· August 2020

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Zika Virus Infects Trabecular Meshwork and Causes Trabeculitis and Glaucomatous Pathology in Mouse Eyes.
Pawan Kumar Singh, Ramesh B Kasetti, Gulab S Zode, Anju Goyal, Mark S Juzych

mSphere· May 2019

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Methods for Analyzing Endoplasmic Reticulum Stress in the Trabecular Meshwork of Glaucoma Models.
Prabhavathi Maddineni, Ramesh B Kasetti, Gulab S Zode

Methods Mol Biol· July 2018

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Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.
Kate E Keller, Sanjoy K Bhattacharya, Theresa Borrás, Thomas M Brunner, Sunee Chansangpetch, Gulab S Zode

Exp Eye Res· June 2018

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Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension.
Ramesh B Kasetti, Prabhavathi Maddineni, Pinkal D Patel, Charles Searby, Val C Sheffield, Gulab S Zode

J Biol Chem· June 2018

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Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork.
Ramesh B Kasetti, Prabhavathi Maddineni, J Cameron Millar, Abbot F Clark, Gulab S Zode

Sci Rep· November 2017

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Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration.
Gaurang C Patel, Tien N Phan, Prabhavathi Maddineni, Ramesh B Kasetti, J Cameron Millar, Gulab S Zode

Am J Pathol· April 2017

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