Publications by authors named "Gum Hwa Lee"

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Dab1 expression level controls Reelin-induced PI3K-Akt activation in early GABAergic neurons.
Kavitha Sajukumar, Prabhakar Yadav, Gum Hwa Lee

Biochem Biophys Res Commun· March 2025

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Preclinical studies and transcriptome analysis in a model of Parkinson's disease with dopaminergic ZNF746 expression.
Ji Hun Kim, Sumin Yang, Hyojung Kim, Dang-Khoa Vo, Han-Joo Maeng, Gum Hwa Lee, Yunjong Lee

Mol Neurodegener· February 2025

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Dual inhibition of aminoacyl-tRNA synthetase interacting multifunctional protein-2 and α-synuclein by steroid derivative is neuroprotective in Parkinson's model.
Jeong-Yong Shin, Min Woo Ha, Ji Hun Kim, Jiwon Cheon, Gum Hwa Lee, Yunjong Lee

iScience· November 2024

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AIMP2 accumulation in brain leads to cognitive deficits and blood secretion in Parkinson's disease.
Heejeong Kim, Jeong-Yong Shin, Sangwoo Ham, Ji Hun Kim, Gum Hwa Lee, Nae-Eung Lee, Yunjong Lee

J Transl Med· October 2024

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Effects of psoralidin on the expression of glutamate decarboxylases and inhibitory synapse development.
Seong-Eun Lee, Gum Hwa Lee

J Asian Nat Prod Res· September 2024

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Maf1 is an intrinsic suppressor against spontaneous neural repair and functional recovery after ischemic stroke.
Chi Kwan Tsang, Qiongjie Mi, Guangpu Su, Gum Hwa Lee, Xuemin Xie

J Adv Res· September 2023

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Survival and functional recovery of primary cortical neurons exposed to actinomycin D.
Seong-Eun Lee, Gum Hwa Lee

Biochem Biophys Res Commun· December 2022

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Reelin Affects Signaling Pathways of a Group of Inhibitory Neurons and the Development of Inhibitory Synapses in Primary Neurons.
Seong-Eun Lee, Gum Hwa Lee

Int J Mol Sci· July 2021

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Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32-Dependent D Dopamine Receptor Signaling and Behaviors.
Raozhou Lin, Lisa N Learman, Chan-Hyun Na, Santosh Renuse, Kevin T Chen, Gum-Hwa Lee

Biol Psychiatry· June 2021

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Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion.
Sangwoo Ham, Seung Pil Yun, Hyojung Kim, Donghoon Kim, Bo Am Seo, Gum Hwa Lee, Yun Il Lee, Yunjong Lee

Sci Transl Med· November 2020

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Luteolin prevents liver from tunicamycin-induced endoplasmic reticulum stress via nuclear factor erythroid 2-related factor 2-dependent sestrin 2 induction.
Kyung Hwan Jegal, Eun Ok Kim, Jae Kwang Kim, Sang Mi Park, Dae Hwa Jung, Gum Hwa Lee

Toxicol Appl Pharmacol· July 2020

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Enhanced phosphorylation of S6 protein in mouse cortical layer V and subplate neurons.
Seong-Eun Lee, Seojin Hwang, Sang-Gun Ahn, Gabriella D'Arcangelo, Gum Hwa Lee

Neuroreport· July 2020

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Induction of E6AP by microRNA-302c dysregulation inhibits TGF-β-dependent fibrogenesis in hepatic stellate cells.
Ji Young Kim, Kyu Min Kim, Ji Hye Yang, Sam Seok Cho, Seung Jung Kim, Gum Hwa Lee

Sci Rep· January 2020

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The regulation of glutamic acid decarboxylases in GABA neurotransmission in the brain.
Seong-Eun Lee, Yunjong Lee, Gum Hwa Lee

Arch Pharm Res· December 2019

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Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates.
Sangwoo Ham, Hyojung Kim, Seojin Hwang, Hyunook Kang, Seung Pil Yun, Yun-Song Lee, Gum Hwa Lee, Yunjong Lee

Mol Cells· June 2019

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Correction to: Psoralidin Stimulates Expression of Immediate-Early Genes and Synapse Development in Primary Cortical Neurons.
Seojin Hwang, Seong-Eun Lee, Sang-Gun Ahn, Gum Hwa Lee

Neurochem Res· February 2019

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Psoralidin Stimulates Expression of Immediate-Early Genes and Synapse Development in Primary Cortical Neurons.
Seojin Hwang, Seong-Eun Lee, Sang-Gun Ahn, Gum Hwa Lee

Neurochem Res· December 2018

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Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons.
Seojin Hwang, Sangwoo Ham, Seong-Eun Lee, Yunjong Lee, Gum Hwa Lee

Neurotoxicology· March 2018

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Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models.
Hyojung Kim, Sangwoo Ham, Joon Yeop Lee, Areum Jo, Gum Hwa Lee, Yun-Song Lee, Yun-Il Lee, Yunjong Lee

Oncotarget· December 2017

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CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation.
Hyojung Kim, Sangwoo Ham, Minkyung Jo, Gum Hwa Lee, Yun-Song Lee, Yunjong Lee

Int J Mol Sci· October 2017

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Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson's disease model.
Sangwoo Ham, Yun-Il Lee, Minkyung Jo, Hyojung Kim, Hojin Kang, Gum Hwa Lee, Yun Song Lee, Yunjong Lee

Sci Rep· April 2017

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VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2.
Seung Pil Yun, Hyojung Kim, Sangwoo Ham, Seung-Hwan Kwon, Gum Hwa Lee, Sang Hun Lee, Yunjong Lee

Cell Death Dis· April 2017

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Therapeutic Strategies for Neuropathic Pain: Potential Application of Pharmacosynthetics and Optogenetics.
Gum Hwa Lee, Sang Seong Kim

Mediators Inflamm· December 2016

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Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123).
Beth Crowell, Gum Hwa Lee, Ina Nikolaeva, Valentina Dal Pozzo, Gabriella D'Arcangelo

eNeuro· September 2016

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New Insights into Reelin-Mediated Signaling Pathways.
Gum Hwa Lee, Gabriella D'Arcangelo

Front Cell Neurosci· May 2016

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