Publications by authors named "Gunther Hartmann"

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Modulating Placebo Effects in Clinical Trials: Study Team Briefing to Optimize Drug-Placebo Differences.
Martin Coenen, Ulrike Bingel, Maria Soledad Berdaguer, Christine Fuhrmann, Robert Németh, Gunther Hartmann

Clin Transl Sci· November 2025

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Expression Analysis of let-7a-5p and miR-21-3p in Extracellular Vesicles Derived from Serum of NSCLC Patients.
Dian Jamel Salih, Katrin S Reiners, Domenico Loizzi, Nicoletta Pia Ardò, Teresa Antonia Santantonio, Gunther Hartmann

Biomedicines· August 2025

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Immunoengineering of a Photocaged 5´-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer.
Sandra Anika Lewash, Vivien Rose McKenney, Christine Wuebben, Janos Ludwig, Racha Hosni, Gunther Hartmann

Angew Chem Int Ed Engl· May 2025

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Case Report: Practical approach to unmask unspecific adverse effects under lipid-lowering medication.
Thomas Büttner, Gunther Hartmann, Martin Coenen

Front Cardiovasc Med· May 2025

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Immune training enhances anti-viral responses and improves outcomes in Pax5 mice susceptible to chronic infection.
Zhe Lu, Olivia Stencel, Wei Liu, Eleni Vasileiou, Haifeng C Xu, Gunther Hartmann

EMBO Mol Med· April 2025

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Isolation and characterization of extracellular vesicles from EGFR mutated lung cancer cells.
Dian Jamel Salih, Katrin S Reiners, Roberta Alfieri, Ahmed Mohammed Salih, Zulema Antonia Percario, Gunther Hartmann

Clin Exp Med· April 2025

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RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I.
Alexander Kirchhoff, Anna-Maria Herzner, Christian Urban, Antonio Piras, Robert Düster, Gunther Hartmann

EMBO J· February 2025

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ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.
Ole Kristian Greiner-Tollersrud, Máté Krausz, Vincent Boehler, Aikaterini Polyzou, Maximilian Seidl, Gunther Hartmann

Cell Rep· November 2024

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Synthetic RIG-I agonist-mediated cancer immunotherapy synergizes with MAP kinase inhibition against BRAF-mutated melanoma.
Christian Grützner, Yu Pan Tan, Patrick Müller, Thais M Schlee-Guimaraes, Marius Jentzsch, Gunther Hartmann

Mol Ther Nucleic Acids· September 2024

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Note on uncertainty in Monte Carlo dose calculations and its relation to microdosimetry.
Günther H Hartmann, Hans G Menzel

Z Med Phys· August 2024

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Induction and antiviral activity of ferret myxovirus resistance (Mx) protein 1 against influenza A viruses.
Rubaiyea Farrukee, Lara S U Schwab, James B Barnes, Andrew G Brooks, Sarah L Londrigan, Gunther Hartmann

Sci Rep· June 2024

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Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release.
Sarah Rösing, Fabian Ullrich, Susann Meisterfeld, Franziska Schmidt, Laura Mlitzko, Gunther Hartmann

Nat Commun· February 2024

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Cooperative activation of human TLR9 and consequences for the clinical development of antisense and CpG oligodeoxynucleotides.
Gunther Hartmann

Mol Ther Nucleic Acids· December 2023

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A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
Ann Kristin de Regt, Kanchan Anand, Katrin Ciupka, Felix Bender, Karl Gatterdam, Gunther Hartmann

Nucleic Acids Res· November 2023

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Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles.
Alexandra Brahmer, Carsten Geiß, Andriani Lygeraki, Elmo Neuberger, Theophilos Tzaridis, Gunther Hartmann

Cell Commun Signal· October 2023

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Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.
Simon Heidegger, Florian Stritzke, Sarah Dahl, Juliane Daßler-Plenker, Laura Joachim, Gunther Hartmann

Cell Rep Med· September 2023

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Poly(I:C) Treatment Prevents Skin Tumor Formation in the Preclinical HPV8 Transgenic Mouse Model.
Martin Hufbauer, Stephanie Rattay, Christian Hagen, Alexander Quaas, Herbert Pfister, Gunther Hartmann

J Invest Dermatol· July 2023

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Dose Recommendations for Common Drugs in Patients with Liver Cirrhosis: A Systematic Literature Review.
Katharina Karsten Dafonte, Lisa Weber, Florian Chmielewski, Anna Maria Böhmer, Philipp Lutz, Gunther Hartmann

Clin Drug Investig· July 2023

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RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma.
Silke Lambing, Yu Pan Tan, Paraskevi Vasileiadou, Stefan Holdenrieder, Patrick Müller, Gunther Hartmann

J Mol Cell Biol· June 2023

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Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode .
Johanna F Scheunemann, Frederic Risch, Julia J Reichwald, Benjamin Lenz, Anna-Lena Neumann, Gunther Hartmann

Vaccines (Basel)· May 2023

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Quantitative protein biomarker panels: a path to improved clinical practice through proteomics.
Johannes Hartl, Florian Kurth, Kai Kappert, David Horst, Michael Mülleder, Gunther Hartmann

EMBO Mol Med· April 2023

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Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.
Julia Wegner, Charlotte Hunkler, Katrin Ciupka, Gunther Hartmann, Martin Schlee

Front Immunol· March 2023

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Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.
Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Gunther Hartmann

J Exp Med· January 2023

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Loss of the Immunomodulatory Transcription Factor BATF2 in Humans Is Associated with a Neurological Phenotype.
Gábor Zsurka, Maximilian L T Appel, Maximilian Nastaly, Kerstin Hallmann, Niels Hansen, Gunther Hartmann

Cells· January 2023

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Correction: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.
Nina Kessler, Susanne F Viehmann, Calvin Krollmann, Karola Mai, Katharina M Kirschner, Gunther Hartmann

J Exp Med· December 2022

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