Publications by authors named "Gunther Spohn"

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Endogenous polyclonal anti-IL-1 antibody responses potentiate IL-1 activity during pathogenic inflammation.
Gunther Spohn, Natalia Arenas-Ramirez, Gregory Bouchaud, Onur Boyman

J Allergy Clin Immunol· June 2017

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Development of an Interleukin-1β Vaccine in Patients with Type 2 Diabetes.
Claudia Cavelti-Weder, Katharina Timper, Eleonora Seelig, Cornelia Keller, Martin Osranek, Gunther Spohn

Mol Ther· May 2016

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Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes.
Gunther Spohn, Christian Schori, Iris Keller, Katja Sladko, Christina Sina

Mol Ther Methods Clin Dev· May 2015

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A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis.
Alain C Tissot, Gunther Spohn, Gary T Jennings, Abdijapar Shamshiev, Michael O Kurrer

Eur J Immunol· March 2013

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Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis.
Stefan Freigang, Franziska Ampenberger, Gunther Spohn, Sebastian Heer, Abdijapar T Shamshiev

Eur J Immunol· July 2011

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A recombinant influenza A virus expressing domain III of West Nile virus induces protective immune responses against influenza and West Nile virus.
Byron E E Martina, Petra van den Doel, Penelope Koraka, Geert van Amerongen, Gunther Spohn

PLoS One· April 2011

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Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice.
Reto Guler, Suraj P Parihar, Gunther Spohn, Pål Johansen, Frank Brombacher

Vaccine· February 2011

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A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice.
Gunther Spohn, Gary T Jennings, Byron Ee Martina, Iris Keller, Markus Beck

Virol J· July 2010

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Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis.
Gunther Spohn, Iris Keller, Markus Beck, Paula Grest, Gary T Jennings

Eur J Immunol· March 2008

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Exploiting viral properties for the rational design of modern vaccines.
Gunther Spohn, Martin F Bachmann

Expert Rev Vaccines· February 2008

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Targeting osteoporosis and rheumatoid arthritis by active vaccination against RANKL.
Gunther Spohn, Martin F Bachmann

Adv Exp Med Biol· December 2007

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Transcriptional regulation of stress response and motility functions in Helicobacter pylori is mediated by HspR and HrcA.
Davide Roncarati, Alberto Danielli, Gunther Spohn, Isabel Delany, Vincenzo Scarlato

J Bacteriol· October 2007

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A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis.
Gunther Spohn, Reto Guler, Pål Johansen, Iris Keller, Muazzam Jacobs

J Immunol· June 2007

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Expression, purification and characterization of the membrane-associated HrcA repressor protein of Helicobacter pylori.
Davide Roncarati, Gunther Spohn, Nunzio Tango, Alberto Danielli, Isabel Delany

Protein Expr Purif· February 2007

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Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles.
Gunther Spohn, Katrin Schwarz, Patrik Maurer, Harald Illges, Narendiran Rajasekaran

J Immunol· November 2005

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CrgA is an inducible LysR-type regulator of Neisseria meningitidis, acting both as a repressor and as an activator of gene transcription.
Raffaele Ieva, Cristina Alaimo, Isabel Delany, Gunther Spohn, Rino Rappuoli

J Bacteriol· May 2005

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Dual control of Helicobacter pylori heat shock gene transcription by HspR and HrcA.
Gunther Spohn, Alberto Danielli, Davide Roncarati, Isabel Delany, Rino Rappuoli

J Bacteriol· May 2004

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An anti-repression Fur operator upstream of the promoter is required for iron-mediated transcriptional autoregulation in Helicobacter pylori.
Isabel Delany, Gunther Spohn, Rino Rappuoli, Vincenzo Scarlato

Mol Microbiol· November 2003

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Therapeutic vaccination to block receptor-ligand interactions.
Gunther Spohn, Martin F Bachmann

Expert Opin Biol Ther· June 2003

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Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site.
Isabel Delany, Gunther Spohn, Ana-Beatriz F Pacheco, Raffaele Ieva, Cristina Alaimo

Mol Microbiol· November 2002

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Growth phase-dependent regulation of target gene promoters for binding of the essential orphan response regulator HP1043 of Helicobacter pylori.
Isabel Delany, Gunther Spohn, Rino Rappuoli, Vincenzo Scarlato

J Bacteriol· September 2002

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Characterization of the HspR-mediated stress response in Helicobacter pylori.
Gunther Spohn, Isabel Delany, Rino Rappuoli, Vincenzo Scarlato

J Bacteriol· June 2002

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In vitro selection of high affinity HspR-binding sites within the genome of Helicobacter pylori.
Isabel Delany, Gunther Spohn, Rino Rappuoli, Vincenzo Scarlato

Gene· January 2002

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