Publications by authors named "Guoquan Yan"

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Large-scale glycoproteome analysis reveals inverted distribution of Neu5Gc and Neu5Ac in mouse liver tissues and cell lines.
Siyuan Kong, Mengxi Wu, Xinmeng Wang, Huanhuan Zhao, Xinwen Zhou, Guoquan Yan

Carbohydr Polym· November 2025

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A Simple and Flexible Strategy for Single-Cell Proteomic Analysis Based on Protein Immobilization and Digestion Tube Reactor.
Wenjia Zhang, Lingxiao Weng, Guoquan Yan, Wei Liu, Xuantang Wang

Anal Chem· November 2025

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Ultrafast Tyrosinase-Mediated Biotinylation of Living Cell Surface Analysis Reveals Novel Cell Surface Proteins Responsible for Influenza A Virus Entry.
Yuying Liang, Jian Chen, Shiyun Ma, Haoru Song, Daobin Feng, Guo-Quan Yan

J Am Chem Soc· September 2025

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A Chromatography-Guided Co-Fractionation Mass Spectrometry Strategy for Rapid Profiling of Drug-Perturbed Protein Complexes.
Wei Liu, Jiayu Tang, Guoquan Yan, Shun Shen, Mingxia Gao

Anal Chem· September 2025

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Molecular architecture of language-related cortical areas revealed by integrative proteomic and connectome analyses.
Jinsong Wu, Zixian Wang, Fengjiao Li, Shuolei Bu, Lianglong Sun, Luhao Yang, Guoquan Yan, Jiaxuan Yang, Jing Yan

Clin Transl Med· September 2025

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Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy.
Yunfeng Yuan, Qianyu Li, Guoquan Yan, Yifei Qian, Wenyun Guo, Yanan Wang, Yanfeng Liu

Adv Sci (Weinh)· May 2025

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Mitochondrial NAD deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm.
Jingjing Zhang, Yuyi Tang, Shan Zhang, Zhuxin Xie, Wenrui Ma, Guoquan Yan, Yang Liu, Yanhui Xu

Nat Cardiovasc Res· March 2025

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Multidimensional Proteomic Landscape Reveals Distinct Activated Pathways Between Human Brain Tumors.
Shuang Yang, Yongtao Zheng, Chengbin Zhou, Jun Yao, Guoquan Yan

Adv Sci (Weinh)· February 2025

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Correcting mitochondrial loss mitigates NOTCH1-related aortopathy in mice.
Yuyi Tang, Jingjing Zhang, Yixuan Fang, Kai Zhu, Jingqiao Zhu, Guoquan Yan, Chenxi Yang, Yang Liu, Yanhui Xu

Nat Cardiovasc Res· February 2025

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A comprehensive view of the molecular features within the serum and serum EV of Alzheimer's disease.
Jiayi Zhang, Xiaoqin Cheng, Anqi Hu, Xin Zhang, Meng Zhang, Guoquan Yan

Analyst· February 2025

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Efficient Cancer Biomarker Screening and Multicancer Detection Enabled by a Multidimensional Serum Proteomic Strategy.
Anqi Hu, Jiayi Zhang, Lei Zhang, Zhenxin Wang, Jiawei Dai, Guoquan Yan

Anal Chem· December 2024

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Unraveling of Phosphotyrosine Signaling Complexes Associated with T Cell Exhaustion Using Multiplex Co-Fractionation/Mass Spectrometry.
Wei Liu, Hailong Yu, Guoquan Yan, Shun Shen, Mingxia Gao

Anal Chem· December 2024

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Uncovering missing glycans and unexpected fragments with pGlycoNovo for site-specific glycosylation analysis across species.
Wen-Feng Zeng, Guoquan Yan, Huan-Huan Zhao, Chao Liu, Weiqian Cao

Nat Commun· September 2024

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Global analysis of N-myristoylation and its heterogeneity by combining N-terminomics and nanographite fluoride-based solid-phase extraction.
Guanghui Ji, Yingying Xiong, Yueyue Li, Guoquan Yan, Jun Yao

Talanta· August 2024

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CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.
Yanfeng Liu, Fan Wang, Guoquan Yan, Yu Tong, Wenyun Guo

Cancer Lett· July 2024

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Picoliter Single-Cell Reactor for Proteome Profiling by In Situ Cell Lysis, Protein Immobilization, Digestion, and Droplet Transfer.
Lingxiao Weng, Guoquan Yan, Wei Liu, Qunfei Tai, Mingxia Gao

J Proteome Res· July 2024

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Integrated Platform for Large-Scale Quantitative Profiling of Phosphotyrosine Signaling Complexes Based on Cofractionation/Mass Spectrometry and Complex-Centric Algorithm.
Wei Liu, Xuantang Wang, Hailong Yu, Guoquan Yan, Shun Shen

Anal Chem· June 2024

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Glyco-signatures in patients with advanced lung cancer during anti-PD-1/PD-L1 immunotherapy.
Xinyi Cao, Zhihuang Hu, Xiangying Sheng, Zhenyu Sun, Lijun Yang, Guoquan Yan

Acta Biochim Biophys Sin (Shanghai)· June 2024

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Immunomagnetic capture and traceless release of native tumor-derived exosomes from human plasma for exploring interaction with recipient cells by aptamer-functionalized nanoflowers.
Haoyang Zheng, Ning Su, Guoquan Yan, Mengran Li, Huimin Chu

Anal Chim Acta· January 2024

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Elucidation of -/-glycosylation and site-specific mapping of sialic acid linkage isomers of SARS-CoV-2 human receptor angiotensin-converting enzyme 2.
Liming Wei, Yuning Chen, Xiaoxiao Feng, Jun Yao, Lei Zhang, Guoquan Yan

Analyst· October 2023

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Rapid and High-Sensitive Phosphoproteomics Elucidated the Spatial Dynamics of the Mouse Brain.
Shuang Yang, Yutong Han, Yafeng Li, Lei Zhang, Guoquan Yan

Anal Chem· July 2023

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Multi-comparative Thermal Proteome Profiling Uncovers New O-GlcNAc Proteins in a System-wide Method.
Guoli Wang, Yang Li, Ting Wang, Jun Wang, Jun Yao, Guoquan Yan

Anal Chem· January 2023

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pGlycoQuant with a deep residual network for quantitative glycoproteomics at intact glycopeptide level.
Siyuan Kong, Pengyun Gong, Wen-Feng Zeng, Biyun Jiang, Xinhang Hou, Yang Zhang, Guoquan Yan, Pengyuan Yang

Nat Commun· December 2022

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AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.
Yanan Wang, Mengjun Luo, Fan Wang, Yu Tong, Linfeng Li, Guoquan Yan, Yanfeng Liu

Nat Commun· November 2022

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Nascent Proteome and Glycoproteome Reveal the Inhibition Role of ALG1 in Hepatocellular Carcinoma Cell Migration.
Xinyi Cao, Yuyin Shao, Peiyi Meng, Zhao Cao, Guoquan Yan

Phenomics· August 2022

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