Publications by authors named "Gurdarshan Singh"

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Scoparone chemical modification into semi-synthetic analogues featuring 3-substitution for their anti-inflammatory activity.
Chetan Kumar, Pankaj Chibber, Ritu Painuli, Syed Assim Haq, Ram A Vishwakarma, Gurdarshan Singh

Mol Divers· August 2024

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Gentiacaulein inhibits glucose transport to induce PRKAA1-mediated autophagy to clear amyloid beta and associated inflammation in primary astrocytes.
Ankita Sharma, Sukhleen Kaur, Abubakar Wani, Dilpreet Kour, Mehboob Ali, Lakhvinder Singh, Gurdarshan Singh

Autophagy Rep· January 2024

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Antifibrotic Agent Mediated Tumor Microenvironment Modulation and Improved Nanomedicine Delivery in Solid Tumor.
Kamalpreet Kaur Sandha, Chittaranjan Behera, Pankaj Chibber, Rajesh Kumar, Amit Kumar, Gurdarshan Singh

Mol Pharm· June 2023

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Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP.
Ashish Dogra, Dilpreet Kour, Abhishek Gour, Mahir Bhardwaj, Swarnendu Bag, Gurdarshan Singh

Drug Chem Toxicol· May 2023

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Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress.
Shipra Bhatt, Ankita Sharma, Ashish Dogra, Priyanka Sharma, Amit Kumar, Gurdarshan Singh

Drug Chem Toxicol· September 2022

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Investigating the Potential Use of Andrographolide as a Coadjuvant in Sickle Cell Anemia Therapy.
Abhishek Gour, Pankul Kotwal, Ashish Dogra, Dilpreet Kour, Sumit Dhiman, Gurdarshan Singh

ACS Omega· April 2022

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Assessment of water quality condition and spatiotemporal patterns in selected wetlands of Punjab, India.
Yadvinder Singh, Gurdarshan Singh, Jasvirinder Singh Khattar, Sophia Barinova, Jasneet Kaur, Davinder Pal Singh

Environ Sci Pollut Res Int· January 2022

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Speckle Tracking Echocardiographic Assessment of Left Ventricular Function by Myocardial Strain Before and After Aortic Valve Replacement.
Gajinder Pal Singh Kaler, Rakesh Mahla, Himanshu Mahla, Sarita Choudhary, Gurdarshan Singh

J Saudi Heart Assoc· January 2022

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Antiarthritic activity of OA-DHZ; a gastroprotective NF-κB/MAPK/COX inhibitor.
Pankaj Chibber, Syed Assim Haq, Anil Kumar, Chetan Kumar, Divya Gupta, Surjeet Singh, Gurdarshan Singh

Cytokine· December 2021

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Pharmacokinetic Assessment of Rottlerin from Using a Highly Sensitive Liquid Chromatography-Tandem Mass Spectrometry-Based Bioanalytical Method.
Diksha Manhas, Abhishek Gour, Nivedita Bhardwaj, Deepak K Sharma, Kuhu Sharma, Gurdarshan Singh

ACS Omega· December 2021

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Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway.
Abubakar Wani, Sweilem B Al Rihani, Ankita Sharma, Brenna Weadick, Rajgopal Govindarajan, Gurdarshan Singh

Autophagy· November 2021

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Glabridin ameliorates methotrexate-induced liver injury via attenuation of oxidative stress, inflammation, and apoptosis.
Ashish Dogra, Divya Gupta, Swarnendu Bag, Irfan Ahmed, Shipra Bhatt, Gurdarshan Singh

Life Sci· August 2021

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Evaluation of analgesic and anti-inflammatory activities and molecular docking analysis of steroidal lactones from Datura stramonium L.
Gourav Chandan, Chetan Kumar, Pankaj Chibber, Ashwani Kumar, Gurdarshan Singh

Phytomedicine· August 2021

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Safranal inhibits NLRP3 inflammasome activation by preventing ASC oligomerization.
Mehak Gupta, Abubakar Wani, Aitizaz Ul Ahsan, Mehboob Ali, Pankaj Chibber, Surjeet Singh, Gurdarshan Singh

Toxicol Appl Pharmacol· July 2021

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Amalgamation of , and approach to establish glabridin as a potential CYP2E1 inhibitor.
Shipra Bhatt, Vinay Kumar, Ashish Dogra, Probir Kumar Ojha, Priya Wazir, Gurdarshan Singh

Xenobiotica· June 2021

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Effect of Concomitant Hydroxyurea Therapy with Rutin and Gallic Acid: Integration of Pharmacokinetic and Pharmacodynamic Approaches.
Abhishek Gour, Ashish Dogra, Dilpreet Kour, Gurdarshan Singh, Ajay Kumar

ACS Omega· June 2021

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Whole-exome sequencing reveals a novel homozygous mutation in the COQ8B gene associated with nephrotic syndrome.
Mohd Fareed, Vikas Makkar, Ravi Angral, Mohammad Afzal, Gurdarshan Singh

Sci Rep· June 2021

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IIIM-941, a Stilbene Derivative Inhibits NLRP3 Inflammasome Activation by Inducing Autophagy.
Mehboob Ali, Mehak Gupta, Abubakar Wani, Ankita Sharma, Mohd Abdullaha, Gurdarshan Singh

Front Pharmacol· June 2021

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Whole-Exome Sequencing Reveals a Rare Variant of Gene Causing Congenital Non-syndromic Hearing Loss Among Large Muslim Families Favoring Consanguinity.
Mohd Fareed, Varun Sharma, Inderpal Singh, Sayeed Ur Rehman, Gurdarshan Singh

Front Genet· May 2021

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Streptomycin sulphate loaded solid lipid nanoparticles show enhanced uptake in macrophage, lower MIC in Mycobacterium and improved oral bioavailability.
Mandeep Singh, Nicola Schiavone, Laura Papucci, Prathiba Maan, Jagdeep Kaur, Gurdarshan Singh, Ramandeep Singh

Eur J Pharm Biopharm· March 2021

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Effect of rutin on pharmacokinetic modulation of diclofenac in rats.
Ashish Dogra, Abhishek Gour, Shipra Bhatt, Priyanka Sharma, Anjna Sharma, Gurdarshan Singh

Xenobiotica· November 2020

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A highly sensitive UPLC-MS/MS method for hydroxyurea to assess pharmacokinetic intervention by phytotherapeutics in rats.
Abhishek Gour, Ashish Dogra, Priya Wazir, Gurdarshan Singh, Utpal Nandi

J Chromatogr B Analyt Technol Biomed Life Sci· October 2020

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Advances in the possible treatment of COVID-19: A review.
Pankaj Chibber, Syed Assim Haq, Irfan Ahmed, Nusrit Iqbal Andrabi, Gurdarshan Singh

Eur J Pharmacol· September 2020

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Anti-inflammatory and analgesic potential of OA-DHZ; a novel semisynthetic derivative of dehydrozingerone.
Pankaj Chibber, Chetan Kumar, Amarinder Singh, Syed Assim Haq, Irfan Ahmed, Surjeet Singh, Gurdarshan Singh

Int Immunopharmacol· June 2020

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Description of Druglike Properties of Safranal and Its Chemistry behind Low Oral Exposure.
Ashish Dogra, Pankul Kotwal, Abhishek Gour, Shipra Bhatt, Gurdarshan Singh

ACS Omega· May 2020

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