Publications by authors named "Guy A Rutter"

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Additive Effects of Dorzagliatin and Glucagon-Like Peptide 1 Receptor Agonism in a Novel Mouse Model of GCK-MODY and in Obese db/db Mice.
Shadai Salazar, Luis Fernando Delgadillo-Silva, Priscila Carapeto, Mohamed Mourad Kenfaoui, Karen Dakessian, Guy A Rutter

Diabetes· January 2026

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I-BET151 modulates glucokinase gene expression and beta cell function in part through changes in FOXO1 expression.
Qing Wei Calvin Ho, James A Miller, Divya Gunaseelan, Rosi Chelliah, Hemapriya Jayaranga Babu, Guy A Rutter

Diabetologia· December 2025

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ER calcium stores contribute to glucose-induced Ca waves and intercellular connectivity in mouse pancreatic islets.
Luis Fernando Delgadillo-Silva, Karen Dakessian, Audrey Provencher-Girard, William E Louch, Guy A Rutter

Cell Calcium· December 2025

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A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins.
Siyi He, Daniel Meister, Samra Khan, Azam Mohammadzadeh, Luis Delgadillo Silva, Guy A Rutter

Cell Death Dis· November 2025

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Editorial: magnetic resonance imaging of metabolic disorders.
An Tang, Martin Lepage, Guy A Rutter, André C Carpentier

Front Endocrinol (Lausanne)· November 2025

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Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.
Yusman Manchanda, Ben Jones, Gaelle Carrat, Zenouska Ramchunder, Piero Marchetti, Guy A Rutter

Diabetes Obes Metab· October 2025

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Effects of SGLT2 ablation or inhibition on corticosterone secretion in high-fat-fed mice: exploring a nexus with cytokine levels.
Niki F Brisnovali, Isabelle Franco, Amira Abdelgawwad, Hio Lam Phoebe Tsou, Thong Huy Cao, Guy A Rutter

Diabetologia· September 2025

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LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes.
Jin Li, Yamei Deng, Marie Gasser, Jie Zhu, Emily M Walker, Guy A Rutter

Nat Metab· August 2025

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Pancreatic α-cells are functionally heterogeneous and sex-dependently regulated by neighboring endocrine cells.
Ya-Chi Huang, Marjan Slak Rupnik, Guy A Rutter

bioRxiv· August 2025

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Serine palmitoyltransferase-mediated de novo sphingolipid biosynthesis is required for normal insulin production and glucose tolerance.
Chloé Amouyal, Shiou Ping Chen, Jessica Denom, Ilyès Raho, Nadim Kassis, Guy A Rutter

bioRxiv· May 2025

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Exploration of individual beta cell function over time effects of hyperglycemia and glucagon-like peptide-1 receptor (GLP1R) agonism.
Luis Fernando Delgadillo-Silva, Shadai Salazar, Livia Lopez Noriega, Audrey Provencher-Girard, Sandra Larouche, Guy A Rutter

bioRxiv· April 2025

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ER calcium stores contribute to glucose-induced Ca waves and intercellular connectivity in mouse pancreatic islets.
Luis Fernando Delgadillo-Silva, Karen Dakessian, Guy A Rutter

bioRxiv· March 2025

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functional profiling and structural characterisation of the human A316T variant.
Liliane El Eid, Kieran Deane-Alder, Roxana-Maria Rujan, Zamara Mariam, Affiong I Oqua, Guy A Rutter

bioRxiv· January 2025

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Severe neonatal hypotonia due to variant affecting function of ZnT5 zinc transporter.
Vadim Dolgin, Pauline Chabosseau, Jacob Bistritzer, Iris Noyman, Orna Staretz-Chacham, Guy A Rutter

JIMD Rep· January 2025

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Roles for the long non-coding RNA / in pancreatic beta cell function.
Livia Lopez-Noriega, Rebecca Callingham, Aida Martinez-Sánchez, Sameena Nawaz, Grazia Pizza, Guy A Rutter

iScience· January 2025

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Binding Kinetics, Bias, Receptor Internalization and Effects on Insulin Secretion and of a Novel GLP-1R/GIPR Dual Agonist, HISHS-2001.
Yusman Manchanda, Ben Jones, Gaelle Carrat, Zenouska Ramchunder, Piero Marchetti, Guy A Rutter

bioRxiv· January 2025

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Investigating the pathogenicity of the recessive p.A251T variant in monogenic diabetes using iPSC-derived beta-like cells.
Ines Cherkaoui, Qian Du, Dieter M Egli, Camille Dion, Harry G Leitch, Guy A Rutter

medRxiv· December 2024

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Exploring pancreatic beta-cell subgroups and their connectivity.
Guy A Rutter, Anne Gresch, Luis Delgadillo Silva, Richard K P Benninger

Nat Metab· November 2024

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Publisher Correction: Exploring pancreatic beta-cell subgroups and their connectivity.
Guy A Rutter, Anne Gresch, Luis Delgadillo Silva, Richard K P Benninger

Nat Metab· November 2024

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Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of -MODY.
Shadai Salazar, Luis Fernando Delgadillo-Silva, Priscila Carapeto, Karen Dakessian, Rana Melhem, Guy A Rutter

bioRxiv· November 2024

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Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence.
Priscila Carapeto, Kanako Iwasaki, Francesko Hela, Jiho Kahng, Ana B Alves-Wagner, Guy A Rutter

Nat Metab· October 2024

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Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells.
Nejc Haberman, Rebecca Cheung, Grazia Pizza, Nevena Cvetesic, Dorka Nagy, Guy A Rutter

FASEB J· August 2024

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Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling.
Yusman Manchanda, Liliane ElEid, Affiong I Oqua, Zenouska Ramchunder, Jiyoon Choi, Guy A Rutter

Sci Signal· July 2024

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Optogenetic β cell interrogation in vivo reveals a functional hierarchy directing the Ca response to glucose supported by vitamin B6.
Luis Fernando Delgadillo-Silva, Emirhan Tasöz, Sumeet Pal Singh, Prateek Chawla, Eleni Georgiadou, Guy A Rutter

Sci Adv· June 2024

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Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells.
Nejc Haberman, Rebecca Cheung, Grazia Pizza, Nevena Cvetesic, Dorka Nagy, Guy A Rutter

bioRxiv· May 2024

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