Publications by authors named "Guy Krippner"

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CD14 Blockade Modulates Macrophage-Mediated Immunological Injury in a Translational Model of Reperfused ST-Segment Elevation Myocardial Infarction.
Aascha A D'Elia Nee Brown, Helen Kiriazis, Jason Bloom, Jonathan Noonan, Ian Hsu, Guy Krippner

JACC Basic Transl Sci· November 2025

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A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
Johannes Zeller, Karen S Cheung Tung Shing, Tracy L Nero, James D McFadyen, Guy Krippner

EMBO Mol Med· January 2023

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Pharmacokinetic study of the novel phosphocholine derivative 3-dibutylaminopropylphosphonic acid by LC-MS coupling.
Michel G Kather, Johannes Zeller, Dietmar Plattner, Bernhard Breit, Sheena Kreuzaler, Guy Krippner

J Chromatogr B Analyt Technol Biomed Life Sci· December 2021

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Platelets in Multiple Sclerosis: Early and Central Mediators of Inflammation and Neurodegeneration and Attractive Targets for Molecular Imaging and Site-Directed Therapy.
Jacqueline M Orian, Claretta S D'Souza, Pece Kocovski, Guy Krippner, Matthew W Hale

Front Immunol· June 2021

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Treatment of type 2 diabetes with the designer cytokine IC7Fc.
Maria Findeisen, Tamara L Allen, Darren C Henstridge, Helene Kammoun, Amanda E Brandon, Guy Krippner

Nature· October 2019

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Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists.
Girdhar Singh Deora, Cheng Xue Qin, Elizabeth A Vecchio, Aaron J Debono, Daniel L Priebbenow, Guy Krippner

J Med Chem· May 2019

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Targeting the CDA1/CDA1BP1 Axis Retards Renal Fibrosis in Experimental Diabetic Nephropathy.
Zhonglin Chai, Tieqiao Wu, Aozhi Dai, Pacific Huynh, Frank Koentgen, Guy Krippner

Diabetes· February 2019

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A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry.
Karen Alt, Brett M Paterson, Erik Westein, Stacey E Rudd, Stan S Poniger, Guy Y Krippner

Angew Chem Int Ed Engl· June 2015

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The structure of vanin 1: a key enzyme linking metabolic disease and inflammation.
Ykelien L Boersma, Janet Newman, Timothy E Adams, Nathan Cowieson, Guy Krippner

Acta Crystallogr D Biol Crystallogr· December 2014

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Efficacy and safety of oral methazolamide in patients with type 2 diabetes: a 24-week, placebo-controlled, double-blind study.
Richard W Simpson, Geoffrey C Nicholson, Joseph Proietto, Alana Sarah, Kerrie M Sanders, Guy Krippner

Diabetes Care· November 2014

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The modified selenenyl amide, M-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE/GPx1 double knockout mice.
Sih Min Tan, Arpeeta Sharma, Derek Y C Yuen, Nada Stefanovic, Guy Krippner

PLoS One· February 2014

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Glycosylation of pramlintide: synthetic glycopeptides that display in vitro and in vivo activities as amylin receptor agonists.
Yusuke Tomabechi, Guy Krippner, Phillip M Rendle, Marie A Squire, Antony J Fairbanks

Chemistry· November 2013

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Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction.
Jonathon Habersberger, Frederik Strang, Amelie Scheichl, Nay Htun, Nicole Bassler, Guy Krippner

Cardiovasc Res· October 2012

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Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo.
Nicky Konstantopoulos, Juan C Molero, Sean L McGee, Briana Spolding, Tim Connor, Guy Krippner

Diabetes· August 2012

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An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus.
Susanne C Feil, Stephanie Hamilton, Guy Y Krippner, Bo Lin, Angela Luttick

ACS Med Chem Lett· April 2012

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An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia.
Denijal Topcic, Wookhyun Kim, Jessica K Holien, Fu Jia, Paul C Armstrong, Guy Krippner

Arterioscler Thromb Vasc Biol· September 2011

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GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors.
Houyuan Hu, Paul C J Armstrong, Elie Khalil, Yung-Chih Chen, Andreas Straub, Guy Krippner

PLoS One· April 2011

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A gene expression signature for insulin resistance.
Nicky Konstantopoulos, Victoria C Foletta, David H Segal, Katherine A Shields, Andrew Sanigorski, Guy Krippner

Physiol Genomics· February 2011

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Structure activity relationship of dendrimer microbicides with dual action antiviral activity.
David Tyssen, Scott A Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Guy Krippner

PLoS One· August 2010

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Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-l-lysine dendrimers.
Lisa M Kaminskas, Brian D Kelly, Victoria M McLeod, Ben J Boyd, Guy Y Krippner

Mol Pharm· September 2009

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The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of PEGylated poly l-lysine dendrimers.
Lisa M Kaminskas, Ben J Boyd, Peter Karellas, Guy Y Krippner, Romina Lessene

Mol Pharm· August 2008

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Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition.
Lisa M Kaminskas, Ben J Boyd, Peter Karellas, Scott A Henderson, Michael P Giannis, Guy Y Krippner

Mol Pharm· February 2008

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Cationic poly-L-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats.
Ben J Boyd, Lisa M Kaminskas, Peter Karellas, Guy Krippner, Romina Lessene

Mol Pharm· January 2007

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Improving the membrane permeability of sialic acid derivatives.
Timothy M Altamore, Peter J Duggan, Guy Y Krippner

Bioorg Med Chem· February 2006

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2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder.
Renee N Brown, Rachel Cameron, David K Chalmers, Stephanie Hamilton, Angela Luttick, Guy Y Krippner

Bioorg Med Chem Lett· April 2005

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