Publications by authors named "Guy Simpson"

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Is oncolytic adenoviral-mediated immunotherapy through p53-overexpression the solution to refractory pancreatic ductal adenocarcinoma?
Lucy J A Harriss, Lewis Stevens, Charles J Rayner, Guy Simpson, Nicola E Annels

Expert Rev Gastroenterol Hepatol· June 2024

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Analysis of ICAM-1 Expression on Bladder Carcinoma Cell Lines and Infectivity and Oncolysis by Coxsackie Virus A21.
Kate Relph, Mehreen Arif, Hardev Pandha, Nicola Annels, Guy R Simpson

Methods Mol Biol· July 2023

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HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme.
Einthavy Arunachalam, William Rogers, Guy R Simpson, Carla Möller-Levet, Gemma Bolton

BMC Cancer· April 2022

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Growth and thermal maturation of the Toba magma reservoir.
Ping-Ping Liu, Luca Caricchi, Sun-Lin Chung, Xian-Hua Li, Qiu-Li Li, Guy Simpson

Proc Natl Acad Sci U S A· November 2021

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Oncolytic Reovirus-Mediated Recruitment of Early Innate Immune Responses Reverses Immunotherapy Resistance in Prostate Tumors.
Nicola E Annels, Guy R Simpson, Mick Denyer, Mehreen Arif, Matt Coffey

Mol Ther Oncolytics· March 2021

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Magma diversity reflects recharge regime and thermal structure of the crust.
Gregor Weber, Guy Simpson, Luca Caricchi

Sci Rep· July 2020

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Modifying the Non-muscle Invasive Bladder Cancer Immune Microenvironment for Optimal Therapeutic Response.
Nicola E Annels, Guy R Simpson, Hardev Pandha

Front Oncol· February 2020

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A Specific Blood Signature Reveals Higher Levels of S100A12: A Potential Bladder Cancer Diagnostic Biomarker Along With Urinary Engrailed-2 Protein Detection.
Ayssar A Elamin, Saskia Klunkelfuß, Susanne Kämpfer, Wulf Oehlmann, Matthias Stehr, Guy R Simpson

Front Oncol· January 2020

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Phase I Trial of an ICAM-1-Targeted Immunotherapeutic-Coxsackievirus A21 (CVA21) as an Oncolytic Agent Against Non Muscle-Invasive Bladder Cancer.
Nicola E Annels, David Mansfield, Mehreen Arif, Carmen Ballesteros-Merino, Guy R Simpson

Clin Cancer Res· October 2019

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Membrane insertion and secretion of the Engrailed-2 (EN2) transcription factor by prostate cancer cells may induce antiviral activity in the stroma.
Natasha Punia, Monika Primon, Guy R Simpson, Hardev S Pandha, Richard Morgan

Sci Rep· March 2019

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Synergistic antitumour effects of rapamycin and oncolytic reovirus.
Charles Comins, Guy Richard Simpson, William Rogers, Kate Relph, Kevin Harrington

Cancer Gene Ther· June 2018

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Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus.
Nicola E Annels, Mehreen Arif, Guy R Simpson, Mick Denyer, Carla Moller-Levet

Mol Ther Oncolytics· June 2018

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Validation of a protein panel for the noninvasive detection of recurrent non-muscle invasive bladder cancer.
Selma Gogalic, Ursula Sauer, Sara Doppler, Andreas Heinzel, Paul Perco, Guy Simpson

Biomarkers· November 2017

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Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells.
Raed A Alharbi, Hardev S Pandha, Guy R Simpson, Ruth Pettengell, Krzysztof Poterlowicz

Oncotarget· October 2017

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Tempo of magma degassing and the genesis of porphyry copper deposits.
Cyril Chelle-Michou, Bertrand Rottier, Luca Caricchi, Guy Simpson

Sci Rep· January 2017

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Cancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advances.
Guy R Simpson, Kate Relph, Kevin Harrington, Alan Melcher, Hardev Pandha

Oncolytic Virother· August 2016

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Multiplatform Biomarker Discovery for Bladder Cancer Recurrence Diagnosis.
Marine De Paoli, Selma Gogalic, Ursula Sauer, Claudia Preininger, Hardev Pandha, Guy Simpson

Dis Markers· August 2016

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HOX transcription factors are potential targets and markers in malignant mesothelioma.
Richard Morgan, Guy Simpson, Sophie Gray, Cheryl Gillett, Zsuzsanna Tabi

BMC Cancer· February 2016

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Adenovirally delivered enzyme prodrug therapy with herpes simplex virus-thymidine kinase in composite tissue free flaps shows therapeutic efficacy in rat models of glioma.
Rohit Seth, Aadil A Khan, Timothy D Pencavel, Michelle J Wilkinson, Joan N Kyula, Guy Simpson

Plast Reconstr Surg· February 2015

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Zircons reveal magma fluxes in the Earth's crust.
Luca Caricchi, Guy Simpson, Urs Schaltegger

Nature· July 2014

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Targeting HOX transcription factors in prostate cancer.
Richard Morgan, Angie Boxall, Kevin J Harrington, Guy R Simpson, Agnieszka Michael

BMC Urol· February 2014

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Targeting the HOX/PBX dimer in breast cancer.
Richard Morgan, Angie Boxall, Kevin J Harrington, Guy R Simpson, Cheryl Gillett

Breast Cancer Res Treat· November 2012

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Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer.
Lucy Heinemann, Guy R Simpson, Angela Boxall, Timothy Kottke, Kate L Relph

BMC Cancer· June 2011

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The effect of cell cycle synchronization on tumor sensitivity to reovirus oncolysis.
Lucy Heinemann, Guy R Simpson, Nicola E Annels, Richard Vile, Alan Melcher

Mol Ther· December 2010

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Expression of RNA interference triggers from an oncolytic herpes simplex virus results in specific silencing in tumour cells in vitro and tumours in vivo.
Anna-Maria Anesti, Guy R Simpson, Toby Price, Hardev S Pandha, Robert S Coffin

BMC Cancer· September 2010

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