Publications by authors named "Gyan Modi"

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FTIR spectroscopy of plasma exosomes reveals distinct lipidomic and proteomic signatures for early Alzheimer's disease detection.
Rishabh Singh, Abhay Mishra, Vipin Kumar, Anu Gupta, Sadaqa Zehra, Gyan Prakash Modi

Clin Chim Acta· December 2025

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Design, synthesis, and biological evaluation of caffeic acid-based novel multifunctional molecules for the management of Alzheimer's disease.
Sunil Kumar, Gyan Modi

Eur J Med Chem· October 2025

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Unveiling Exosome Potential: Transforming Treatments for Neurodegeneration.
Ankit Tiwari, Brijesh Singh, Gireesh Kumar Singh, Jairam Meena, Ashish Kumar Agrawal, Gyan Modi

ACS Appl Bio Mater· July 2025

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New D-π-A-Based Coumarin- Derived Fluorescent Theranostic Probes With Broad-Spectrum Antimicrobial Activity.
Himanshu Rai, Atul Kumar Tiwari, Aishwarya Nikhil, Ankit Tiwari, Prahalad Singh Bharti, Gyan Modi

Arch Pharm (Weinheim)· July 2025

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A simplified and efficient method for isolating small extracellular vesicles for comparative and comprehensive translational research.
Prahalad Singh Bharti, Komal Rani, Rishabh Singh, Sanskriti Rai, Simran Rastogi, Gyan Prakash Modi

Sci Rep· May 2025

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Discovery of novel hybrid tryptamine-rivastigmine molecules as potent AChE and BChE inhibitors exhibiting multifunctional properties for the management of Alzheimer's disease.
Gauri Shankar, Prabhat Kumar, Sanskriti Rai, Aparajita Ghosh, Tanmaykumar Varma, Gyan Modi

Eur J Med Chem· February 2025

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Discovery of novel substituted (Z)-N'-hydroxy-3-(3-phenylureido)benzimidamide derivatives as multifunctional molecules targeting pathological hallmarks of Alzheimer's disease.
Gauri Shankar, C Praveen Kumar, Meenu Yadav, Aparajita Ghosh, Samir Ranjan Panda, Gyan Modi

Eur J Med Chem· December 2024

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Repurposing the in-house generated Alzheimer's disease targeting molecules through computational and preliminary in-vitro studies for the management of SARS-coronavirus-2.
Gourav Singh, Jobin Thomas, Sahil Wadhawa, Anurag Kashyap, Syed Ajijur Rahaman, Gyan Modi

Mol Divers· October 2024

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Molecular Targets of Valeric Acid: A Bioactive Natural Product for Endocrine, Metabolic, and Immunological Disorders.
Bindu Kumari, Usha Kumari, Dhananjay Kumar Singh, Gulam Mohammed Husain, Dinesh Kumar Patel, Gyan Prakash Modi

Endocr Metab Immune Disord Drug Targets· September 2024

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Design, Synthesis, and Biological Evaluation of Ferulic Acid-Piperazine Derivatives Targeting Pathological Hallmarks of Alzheimer's Disease.
Gourav Singh, Sunil Kumar, Samir Ranjan Panda, Prabhat Kumar, Sanskriti Rai, Gyan Modi

ACS Chem Neurosci· August 2024

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Extraction, isolation, synthesis, and biological evaluation of novel piperic acid derivatives for the treatment of Alzheimer's disease.
Jitendra Kumar, Gauri Shankar, Sunil Kumar, Jobin Thomas, Neha Singh, Gyan Modi

Mol Divers· June 2024

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Circulating small extracellular vesicles in Alzheimer's disease: a case-control study of neuro-inflammation and synaptic dysfunction.
Rishabh Singh, Sanskriti Rai, Prahalad Singh Bharti, Sadaqa Zehra, Priya Kumari Gorai, Gyan Prakash Modi

BMC Med· June 2024

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Design, Synthesis, and Biological Evaluation of Ferulic Acid Template-Based Novel Multifunctional Ligands Targeting NLRP3 Inflammasome for the Management of Alzheimer's Disease.
Gourav Singh, Gauri Shankar, Samir Ranjan Panda, Sunil Kumar, Sanskriti Rai, Gyan Modi

ACS Chem Neurosci· April 2024

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Spectroscopic insight into breast cancer: profiling small extracellular vesicles lipids via infrared spectroscopy for diagnostic precision.
Abhay Mishra, Sadaqa Zehra, Prahalad Kumar Bharti, Sandeep R Mathur, Piyush Ranjan, Gyan Prakash Modi

Sci Rep· April 2024

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Ferroptosis and its modulators: A raising target for cancer and Alzheimer's disease.
Gourav Singh, Prashant Kesharwani, Gireesh Kumar Singh, Saroj Kumar, Anjaneyulu Putta, Gyan Modi

Bioorg Med Chem· January 2024

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Circulating plasma miR-23b-3p as a biomarker target for idiopathic Parkinson's disease: comparison with small extracellular vesicle miRNA.
Sanskriti Rai, Prahalad Singh Bharti, Rishabh Singh, Simran Rastogi, Komal Rani, Gyan Prakash Modi

Front Neurosci· November 2023

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Synthesis of phenylethanoid glycosides from acrylic esters of glucose and aryldiazonium salts via palladium-catalyzed cross-coupling reactions and evaluation of their anti-Alzheimer activity.
Aswathi C Narayanan, Rapelly Venkatesh, Shweta Singh, Gourav Singh, Gyan Modi

Carbohydr Res· October 2023

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Fluorescence-tagged salivary small extracellular vesicles as a nanotool in early diagnosis of Parkinson's disease.
Simran Rastogi, Komal Rani, Sanskriti Rai, Rishabh Singh, Prahalad Singh Bharti, Gyan Prakash Modi

BMC Med· September 2023

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Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer's Disease.
Himanshu Rai, Sarika Gupta, Saroj Kumar, Jian Yang, Sushil K Singh, Gyan Modi

J Med Chem· July 2022

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Multicomponent Synthesis of -Benzyl Dithiocarbamates from -Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer's Disease.
Rapelly Venkatesh, Gauri Shankar, Aswathi C Narayanan, Gyan Modi, Shahulhameed Sabiah

J Org Chem· May 2022

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Exploration of Neuroprotective Properties of a Naturally Inspired Multifunctional Molecule (F24) against Oxidative Stress and Amyloid β Induced Neurotoxicity in Alzheimer's Disease Models.
Yash Pal Singh, Navneet Kumar, Khushbu Priya, Brijesh Singh Chauhan, Gauri Shankar, Gyan Modi

ACS Chem Neurosci· January 2022

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The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Infections.
Gyan Modi, Gary M Marqus, Mohana Rao Vippila, Deviprasad R Gollapalli, Youngchang Kim

ACS Infect Dis· November 2021

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Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.
Yash Pal Singh, Gauri Shankar, Shagufta Jahan, Gourav Singh, Navneet Kumar, Gyan Modi

Bioorg Med Chem· September 2021

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Identification of high affinity and low molecular alternatives of boceprevir against SARS-CoV-2 main protease: A virtual screening approach.
Subhomoi Borkotoky, Manidipa Banerjee, Gyan Prakash Modi, Vikash Kumar Dubey

Chem Phys Lett· May 2021

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A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease.
Yash Pal Singh, Himanshu Rai, Gourav Singh, Gireesh Kumar Singh, Sunil Mishra, Gyan Modi

Eur J Med Chem· April 2021

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