Publications by authors named "Gyoonhee Han"

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Discovery of PAR2 antagonists through fragment molecular orbital-based hotspot analysis and allosteric sodium site dynamics simulations.
Junyoung Park, Hocheol Lim, Yechan Lee, Taegun Kim, Heejeong Song, Gyoonhee Han

Bioorg Chem· December 2025

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Correction to "Development and Evaluation of Indole-Based Phospholipase D Inhibitors for Lung Cancer Immunotherapy".
Doona Song, Seong Hun Lim, Yeji Kim, Hyesung Lee, Taehyun Kim, Gyoonhee Han

J Med Chem· October 2025

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Structure-based optimization of TEAD inhibitors: Exploring a novel subpocket near Glu347 for the treatment of NF2-mutant cancer.
Jin Kwan Kim, Jinhyuk Kim, Hadong Kim, Haiyan Jin, Youngki Yoo, Han-Joo Maeng, Gyoonhee Han

Bioorg Chem· June 2025

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Development and Evaluation of Indole-Based Phospholipase D Inhibitors for Lung Cancer Immunotherapy.
Doona Song, Seong Hun Lim, Yeji Kim, Hyesung Lee, Taehyun Kim, Gyoonhee Han

J Med Chem· March 2025

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Combination of Aβ40, Aβ42, and Tau Plasma Levels to Distinguish Amyloid-PET Positive Alzheimer Patients from Normal Controls.
Seungyeop Baek, Jinny Claire Lee, Byung Hyun Byun, Su Yeon Park, Jeong Ho Ha, Gyoonhee Han

Exp Neurobiol· February 2025

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Propolis suppresses atopic dermatitis through targeting the MKK4 pathway.
Ye-Ryeong Cho, Eui Jeong Han, Eun Heo, Arachchige Maheshika Kumari Jayasinghe, Jihyun Won, Gyoonhee Han

Biofactors· December 2024

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Pan-Transcriptional Enhanced Associated Domain Palmitoylation Pocket Covalent Inhibitor.
Jinhyuk Kim, Hadong Kim, Jongwan Kim, Seon Yeon Cho, Sungho Moon, Hanseong Kim, Gyoonhee Han

J Med Chem· November 2024

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Discovery of Protease-activated receptor 2 antagonists derived from phenylalanine for the treatment of breast cancer.
Taegun Kim, Yechan Lee, Hocheol Lim, Yeonhwa Kim, Haeun Cho, Gyoonhee Han

Bioorg Chem· September 2024

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Novel small molecule-mediated restoration of the surface expression and anion exchange activity of mutated pendrin causing Pendred syndrome and DFNB4.
Jinsei Jung, Shin Hye Noh, Sungwoo Jo, Doona Song, Min Jin Kang, Gyoonhee Han

Biomed Pharmacother· November 2023

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A newly developed PLD1 inhibitor ameliorates rheumatoid arthritis by regulating pathogenic T and B cells and inhibiting osteoclast differentiation.
Jin-Sil Park, SeungCheon Yang, Doona Song, Sung-Min Kim, JeongWon Choi, Gyoonhee Han

Immunol Lett· November 2023

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Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy.
Minjee Kim, Hyeyoung Kim, Bu-Gyeong Kang, Jooyoung Lee, Taegun Kim, Gyoonhee Han

Theranostics· September 2023

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Inhibition of CXXC5 function rescues Alzheimer's disease phenotypes by restoring Wnt/β-catenin signaling pathway.
Minguen Yoon, Heejene Kim, Heewon Shin, HeeYang Lee, Min-Jeong Kang, Gyoonhee Han

Pharmacol Res· August 2023

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Combination of the LARS1 Inhibitor, BC-LI-0186 with a MEK1/2 Inhibitor Enhances the Anti-Tumor Effect in Non-Small Cell Lung Cancer.
Sang Hoon Lee, Eun Young Kim, Jung Min Han, Gyoonhee Han, Yoon Soo Chang

Cancer Res Treat· July 2023

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AB-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus.
Jina Ahn, Ji Eun Yu, Hanna Kim, Jemin Sung, Gyoonhee Han

Toxins (Basel)· June 2023

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CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD.
Yeong Chan Ryu, Jiyeon Park, You-Rin Kim, Sehee Choi, Geon-Uk Kim, Gyoonhee Han

Cells· February 2023

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Structural optimization of novel Ras modulator for treatment of Colorectal cancer by promoting β-catenin and Ras degradation.
Seonghwi Choi, Hyuntae Kim, Won-Ji Ryu, Kang-Yell Choi, Taegun Kim, Gyoonhee Han

Bioorg Chem· January 2023

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Selective cytotoxicity of a novel mitochondrial complex I inhibitor, YK-135, against EMT-subtype gastric cancer cell lines due to impaired glycolytic capacity.
Yeojin Sung, Seungbin Cha, Sang Bum Kim, Hakhyun Kim, Seonghwi Choi, Gyoonhee Han

BMB Rep· December 2022

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Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling.
Yeong Chan Ryu, You-Rin Kim, Jiyeon Park, Sehee Choi, Won-Ji Ryu, Gyoonhee Han

Pharmaceutics· December 2022

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Wnt/β-catenin signaling activator restores hair regeneration suppressed by diabetes mellitus.
Yeong Chan Ryu, You-Rin Kim, Jiyeon Park, Sehee Choi, Geon-Uk Kim, Gyoonhee Han

BMB Rep· November 2022

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Hemsl. Extract and Its Active Component Hesperidin Accelerate Cutaneous Wound Healing via Activation of Wnt/β-Catenin Signaling Pathway.
Minguen Yoon, Seol Hwa Seo, Seonghwi Choi, Gyoonhee Han, Kang-Yell Choi

Molecules· October 2022

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Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer.
Won Chan Hwang, Doona Song, Hyesung Lee, Changmok Oh, Seong Hun Lim, Gyoonhee Han

Exp Mol Med· September 2022

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Indirubin-3'-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction.
Doona Song, Yunja Lee, Min-Jeong Kang, Jae Won Kim, Soung-Hoon Lee, Gyoonhee Han

Bioorg Chem· April 2022

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Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2.
Hanbyeol Moon, Jung-Won Choi, Byeong-Wook Song, Il-Kwon Kim, Soyeon Lim, Gyoonhee Han

Cells· February 2022

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Development of a DABCO-Succinic Acid Based Catalytic System for the Aza-Michael Addition and Aza-Michael/Knoevenagel Tandem Reaction of Thiazolidine-2,4-dione to Electron Deficient Alkenes.
Kilsoo Jung, Sunmi Kim, Seonghwi Choi, Ikyon Kim, Gyoonhee Han

J Org Chem· December 2021

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Suppressing Pyroptosis Augments Post-Transplant Survival of Stem Cells and Cardiac Function Following Ischemic Injury.
Chang Youn Lee, Seahyoung Lee, Seongtae Jeong, Jiyun Lee, Hyang-Hee Seo, Gyoonhee Han

Int J Mol Sci· July 2021

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