Publications by authors named "Hack-Sun Choi"

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Pharmacological inhibition of Ubiquitin-Specific Peptidase 10 (USP10) with spautin-1 attenuates adipogenesis through CCAAT/Enhancer-Binding Protein Beta (C/EBPβ) destabilization.
Zolzaya Erdenebileg, Desy Damayanti Simamora, Joong-Kwon Park, Rosana Nogueira, Young Bin Kim, Jeong-Yun Choi, Hack Sun Choi

Mol Biomed· December 2025

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Protective effects of lipid mediators, obtained from docosahexaenoic acid via soybean lipoxygenase, on lipopolysaccharide‑induced acute lung injury through the NF‑κB and Nrf2/HO‑1 signaling pathways.
Yan Su, Hack Sun Choi, Soon Kyu Kwon, Yunjon Han, Soon-Chang Cho, Jong Hyun Choi

Mol Med Rep· September 2025

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Auranofin, an antirheumatic drug, shows anticancer stem cell potential via suppression of the Stat3 signal.
Seung-Yeon Ko, Yuna Kim, Jin Sun Chung, Young Bin Kim, Su-Lim Kim, Hack Sun Choi

BMB Rep· July 2025

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LPS stimulation-induced regulation of LECT2 expression via TLR4 in hepatocytes.
Ayoub El Bakiallah, Desy Simamora Damayanti, Rosana Nogueira, Hack Sun Choi, Kyung-Hee Chun

BMB Rep· June 2025

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Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase alleviate ovalbumin‑induced allergic asthma in mice by reducing airway inflammation and oxidative stress.
Yan Su, Hack Sun Choi, Soon Kyu Kwon, Yunjon Han, Soon-Chang Cho, Jong Hyun Choi

Mol Med Rep· April 2025

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Sertaconazole, an Imidazole Antifungal Agent, Suppresses the Stemness of Breast Cancer Cells by Inhibiting Stat3 Signaling.
Su-Lim Kim, Won-Kyung Hong, Hack Sun Choi, Dong-Sun Lee

In Vivo· December 2024

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Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase attenuate RANKL-induced osteoclast differentiation and rheumatoid arthritis.
Yan Su, Yunjon Han, Hack Sun Choi, Gil-Yong Lee, Hee Won Cho, Heonsik Choi, Jong Hyun Choi

Biomed Pharmacother· February 2024

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Lipid mediators derived from DHA alleviate DNCB-induced atopic dermatitis and improve the gut microbiome in BALB/c mice.
Yan Su, Yunjon Han, Hack Sun Choi, Gil-Yong Lee, Hee Won Cho, Heonsik Choi, Jong Hyun Choi

Int Immunopharmacol· November 2023

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BRD4/nuclear PD-L1/RelB circuit is involved in the stemness of breast cancer cells.
Su-Lim Kim, Hack Sun Choi, Dong-Sun Lee

Cell Commun Signal· November 2023

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13-Oxo-9Z,11E-octadecadienoic Acid Down-regulates c-Myc and Attenuates Breast Cancer Cell Stemness.
Yu-Chan Ko, Hack Sun Choi, Su-Lim Kim, Dong-Sun Lee

In Vivo· May 2023

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Isophysalin A Inhibits the Stemness of Breast Cancer Cells Possibly Stat3 and IL-6 Signaling.
Yu-Chan Ko, Hack Sun Choi, Su-Lim Kim, Dong-Sun Lee

Anticancer Res· March 2023

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Effects of Fish Oil, Lipid Mediators, Derived from Docosahexaenoic Acid, and Their Co-Treatment against Lipid Metabolism Dysfunction and Inflammation in HFD Mice and HepG2 Cells.
Yan Su, Hack-Sun Choi, Jong-Hyun Choi, Hee-Sik Kim, Gil-Yong Lee, Heonsik Choi

Nutrients· January 2023

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7,15-Dihydroxy-16,17-epoxy-docosapentaenoic Acid Overcomes Chemoresistance of 5-Fluorouracil by Suppressing the Infiltration of Tumor-Associated Macrophages and Inhibiting the Activation of Cancer Stem Cells in a Colorectal Cancer Xenograft Model.
Yan Su, Hack Sun Choi, Jong Hyun Choi, Hee-Sik Kim, Yong-Suk Jang

Mar Drugs· January 2023

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Protective effect of 17S‑epoxy‑docosapentaenoic acid against dextran sulfate sodium induced ulcerative colitis in BALB/c mice.
Lifang Wang, Hack Sun Choi, Yan Su, Binna Lee, Jong Hyun Choi

Mol Med Rep· September 2022

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Dihydroconiferyl Ferulate Isolated from H.Lév. Suppresses Stemness of Breast Cancer Cells via Nuclear EGFR/c-Myc Signaling.
Yu-Chan Ko, Ren Liu, Hu-Nan Sun, Bong-Sik Yun, Hack Sun Choi

Pharmaceuticals (Basel)· May 2022

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The docosahexaenoic acid derivatives, diHEP-DPA and TH-DPA, synthesized via recombinant lipoxygenase, ameliorate disturbances in lipid metabolism and liver inflammation in high fat diet-fed mice.
Lifang Wang, Hack Sun Choi, Yan Su, Jung-Hyun Ju, Sun-Yeon Heo

Life Sci· February 2022

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Anti-Inflammatory Effects of (9Z,11E)-13-Oxooctadeca-9,11-dienoic Acid (13-KODE) Derived from L. on Lipopolysaccharide-Stimulated Murine Macrophage via NF-kB and MAPK Inhibition and Nrf2/HO-1 Signaling Activation.
Yu-Chan Ko, Hack Sun Choi, Su-Lim Kim, Bong-Sik Yun, Dong-Sun Lee

Antioxidants (Basel)· January 2022

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Primaquine Inhibits the Endosomal Trafficking and Nuclear Localization of EGFR and Induces the Apoptosis of Breast Cancer Cells by Nuclear EGFR/Stat3-Mediated c-Myc Downregulation.
Ji-Hyang Kim, Hack-Sun Choi, Dong-Sun Lee

Int J Mol Sci· November 2021

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Extracellular Vesicles from Korean fragile and Negatively Regulate Melanin Synthesis.
Bohee Jang, Heesung Chung, Hyejung Jung, Hyun-Kuk Song, Eunhye Park, Hack Sun Choi

Mol Cells· October 2021

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5-Desmethylsinensetin isolated from Artemisia princeps suppresses the stemness of breast cancer cells via Stat3/IL-6 and Stat3/YAP1 signaling.
Ren Liu, Hack Sun Choi, Yu-Chan Ko, Bong-Sik Yun, Dong-Sun Lee

Life Sci· September 2021

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7S,15R-Dihydroxy-16S,17S-Epoxy-Docosapentaenoic Acid, a Novel DHA Epoxy Derivative, Inhibits Colorectal Cancer Stemness through Repolarization of Tumor-Associated Macrophage Functions and the ROS/STAT3 Signaling Pathway.
Lifang Wang, Hack Sun Choi, Yan Su, Binna Lee, Jae Jun Song

Antioxidants (Basel)· September 2021

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5-Hydroxymaltol Derived from Beetroot Juice through Fermentation Suppresses Inflammatory Effect and Oxidant Stress via Regulating NF-kB, MAPKs Pathway and NRF2/HO-1 Expression.
Su-Lim Kim, Hack Sun Choi, Yu-Chan Ko, Bong-Sik Yun, Dong-Sun Lee

Antioxidants (Basel)· August 2021

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Physalin A, 13,14-Seco-16, 24-Cyclo-Steroid, Inhibits Stemness of Breast Cancer Cells by Regulation of Hedgehog Signaling Pathway and Yes-Associated Protein 1 (YAP1).
Yu-Chan Ko, Hack Sun Choi, Ren Liu, Dong-Sun Lee

Int J Mol Sci· August 2021

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13,20-Dihydroxydocosahexaenoic Acid, a Novel Dihydroxy- DHA Derivative, Inhibits Breast Cancer Stemness through Regulation of the Stat3/IL-6 Signaling Pathway by Inducing ROS Production.
Lifang Wang, Hack Sun Choi, Binna Lee, Jong Hyun Choi, Yong-Suk Jang

Antioxidants (Basel)· March 2021

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The Antiasthma Medication Ciclesonide Suppresses Breast Cancer Stem Cells through Inhibition of the Glucocorticoid Receptor Signaling-Dependent YAP Pathway.
Su-Lim Kim, Hack Sun Choi, Ji-Hyang Kim, Dong-Sun Lee

Molecules· December 2020

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