Publications by authors named "Hagit Achdout"

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Induction of Superior Systemic and Mucosal Protective Immunity to SARS-CoV-2 by Nasal Administration of a VSV-ΔG-Spike Vaccine.
Yfat Yahalom-Ronen, Sharon Melamed, Boaz Politi, Noam Erez, Hadas Tamir, Hagit Achdout

Vaccines (Basel)· May 2024

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Synergistic effect of two human-like monoclonal antibodies confers protection against orthopoxvirus infection.
Hadas Tamir, Tal Noy-Porat, Sharon Melamed, Lilach Cherry-Mimran, Moria Barlev-Gross, Hagit Achdout

Nat Commun· April 2024

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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Melissa L Boby, Daren Fearon, Matteo Ferla, Mihajlo Filep, Lizbé Koekemoer, Hagit Achdout

Science· November 2023

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Generation of recombinant mAbs to vaccinia virus displaying high affinity and potent neutralization.
Tal Noy-Porat, Hadas Tamir, Ron Alcalay, Ronit Rosenfeld, Eyal Epstein, Hagit Achdout

Microbiol Spectr· September 2023

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Identification of T-Cell Epitopes Using a Combined In-Silico and Experimental Approach in a Mouse Model for SARS-CoV-2.
Noam Erez, Hagit Achdout, Yfat Yahalom-Ronen, Shimrit Adutler-Lieber, Liat Bar-On

Curr Issues Mol Biol· September 2023

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VSV-ΔG-Spike Candidate Vaccine Induces Protective Immunity and Protects K18-hACE2 Mice against SARS-CoV-2 Variants.
Yfat Yahalom-Ronen, Hadas Tamir, Sharon Melamed, Boaz Politi, Hagit Achdout

Viruses· June 2023

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ICAMs are dispensable for influenza clearance and anti-viral humoral and cellular immunity.
Stav Kozlovski, Ofer Regev, Anita Sapoznikov, Marina Kizner, Hagit Achdout

Front Immunol· March 2023

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Antiviral activity of glucosylceramide synthase inhibitors in alphavirus infection of the central nervous system.
Roy Avraham, Sharon Melamed, Hagit Achdout, Noam Erez, Ofir Israeli

Brain Commun· March 2023

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Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern.
Hadas Cohen-Dvashi, Jonathan Weinstein, Michael Katz, Maayan Eilon-Ashkenazy, Yuval Mor, Hagit Achdout

iScience· October 2022

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Monkeypox DNA levels correlate with virus infectivity in clinical samples, Israel, 2022.
Nir Paran, Yfat Yahalom-Ronen, Ohad Shifman, Shirley Lazar, Ronen Ben-Ami, Hagit Achdout

Euro Surveill· September 2022

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rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits.
Amir Rosner, Michal Steiner, Sharon Melamed, Boaz Politi, Einat Vitner, Hagit Achdout

Arch Toxicol· August 2022

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Matrix Metalloproteinases Expression Is Associated with SARS-CoV-2-Induced Lung Pathology and Extracellular-Matrix Remodeling in K18-hACE2 Mice.
Hila Gutman, Moshe Aftalion, Sharon Melamed, Boaz Politi, Reinat Nevo, Hagit Achdout

Viruses· July 2022

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Prolonged Protective Immunity Induced by Mild SARS-CoV-2 Infection of K18-hACE2 Mice.
Liat Bar-On, Moshe Aftalion, Efi Makdasi, David Gur, Ron Alcalay, Hagit Achdout

Vaccines (Basel)· April 2022

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Preliminary nonclinical safety and immunogenicity of an rVSV-ΔG-SARS-CoV-2-S vaccine in mice, hamsters, rabbits and pigs.
Noa Madar-Balakirski, Amir Rosner, Sharon Melamed, Boaz Politi, Michal Steiner, Hagit Achdout

Arch Toxicol· March 2022

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Neutralization of SARS-CoV-2 Variants by rVSV-ΔG-Spike-Elicited Human Sera.
Yfat Yahalom-Ronen, Noam Erez, Morly Fisher, Hadas Tamir, Boaz Politi, Hagit Achdout

Vaccines (Basel)· February 2022

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Induction of Innate Immune Response by TLR3 Agonist Protects Mice against SARS-CoV-2 Infection.
Hadas Tamir, Sharon Melamed, Noam Erez, Boaz Politi, Yfat Yahalom-Ronen, Hagit Achdout

Viruses· January 2022

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SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection.
Abigael Eva Chaouat, Hagit Achdout, Inbal Kol, Orit Berhani, Gil Roi

PLoS Pathog· December 2021

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Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity.
Hagit Achdout, Einat B Vitner, Boaz Politi, Sharon Melamed, Yfat Yahalom-Ronen

Nat Commun· October 2021

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Monitoring Group Activity of Hamsters and Mice as a Novel Tool to Evaluate COVID-19 Progression, Convalescence, and rVSV-ΔG-Spike Vaccination Efficacy.
Sharon Melamed, Boaz Politi, Ettie Grauer, Hagit Achdout, Moshe Aftalion

Front Bioeng Biotechnol· October 2021

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Human Kidney Spheroids and Monolayers Provide Insights into SARS-CoV-2 Renal Interactions.
Dorit Omer, Oren Pleniceanu, Yehudit Gnatek, Michael Namestnikov, Osnat Cohen-Zontag, Hagit Achdout

J Am Soc Nephrol· September 2021

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Implementation of Adenovirus-Mediated Pulmonary Expression of Human ACE2 in HLA Transgenic Mice Enables Establishment of a COVID-19 Murine Model for Assessment of Immune Responses to SARS-CoV-2 Infection.
Theodor Chitlaru, Erez Bar-Haim, Liat Bar-On, Shahar Rotem, Hila Cohen, Hagit Achdout

Pathogens· July 2021

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Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
Reut Falach, Liat Bar-On, Shlomi Lazar, Tamar Kadar, Ohad Mazor, Hagit Achdout

JCI Insight· June 2021

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Spike vs nucleocapsid SARS-CoV-2 antigen detection: application in nasopharyngeal swab specimens.
Moria Barlev-Gross, Shay Weiss, Amir Ben-Shmuel, Assa Sittner, Keren Eden, Hagit Achdout

Anal Bioanal Chem· May 2021

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Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice.
Tal Noy-Porat, Adva Mechaly, Yinon Levy, Efi Makdasi, Ron Alcalay, Hagit Achdout

iScience· May 2021

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Neutralizing Monoclonal Anti-SARS-CoV-2 Antibodies Isolated from Immunized Rabbits Define Novel Vulnerable Spike-Protein Epitope.
Efi Makdasi, Yinon Levy, Ron Alcalay, Tal Noy-Porat, Eran Zahavy, Hagit Achdout

Viruses· March 2021

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