Publications by authors named "Haibin Ruan"

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Cutting the Gordian knot: Untangling gasdermin C from pyroptosis.
Zhaoyu Lin, Hai-Bin Ruan

Immunity· October 2025

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Corrigendum to "Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia" [Genes & Dis 11 (2024) 413-429].
Dongsheng Zhang, Wenjuan Tang, Haitao Niu, William Tse, Hai-Bin Ruan

Genes Dis· September 2025

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Ketone body driven lipid remodeling supports thermogenic adaptation to fasting.
Zahra Moazzami, Eric D Queathem, Jiawen Ma, Qian Chen, Rini Arianti, Hai-Bin Ruan

bioRxiv· June 2025

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Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation.
Eric D Queathem, Zahra Moazzami, David B Stagg, Alisa B Nelson, Kyle Fulghum, Hai-Bin Ruan

Sci Adv· January 2025

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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Kautilya K Jena, Julien Mambu, Daniel Boehmer, Benedetta Sposito, Virginie Millet, Hai-Bin Ruan

Cell· December 2024

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Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation.
Eric D Queathem, Zahra Moazzami, David B Stagg, Alisa B Nelson, Kyle Fulghum, Hai-Bin Ruan

bioRxiv· July 2024

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To die or not to die: Gasdermins in intestinal health and disease.
Zhaoyu Lin, Qianyue Chen, Hai-Bin Ruan

Semin Immunol· February 2024

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Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia.
Dongsheng Zhang, Wenjuan Tang, Haitao Niu, William Tse, Hai-Bin Ruan

Genes Dis· January 2024

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Supraclavicular brown adipocytes originate from Tbx1+ myoprogenitors.
Zan Huang, Chenxin Gu, Zengdi Zhang, Rini Arianti, Aneesh Swaminathan, Hai-Bin Ruan

PLoS Biol· December 2023

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Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH.
Haiguang Wang, Fanta Barrow, Gavin Fredrickson, Kira Florczak, Huy Nguyen, Hai-Bin Ruan

bioRxiv· October 2023

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O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors.
Zengdi Zhang, Zan Huang, Mohamed Awad, Mohammed Elsalanty, James Cray, Hai-Bin Ruan

Elife· March 2023

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Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity.
Xiwen Xiong, Chenyan Yang, Wei-Qi He, Jiahui Yu, Yue Xin, Hai-Bin Ruan

Nat Commun· September 2022

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Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Deletion.
Xiwen Xiong, Rong Huang, Zun Li, Chenyan Yang, Qingzhi Wang, Hai-Bin Ruan

Int J Mol Sci· September 2022

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Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C.
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Hai-Bin Ruan

Immunity· July 2022

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An OGT-STAT5 Axis in Regulatory T Cells Controls Energy and Iron Metabolism.
Zengdi Zhang, Oscar C Salgado, Bing Liu, Zahra Moazzami, Kristin A Hogquist, Hai-Bin Ruan

Front Immunol· July 2022

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Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C.
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Hai-Bin Ruan

Immunity· April 2022

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Brown adipose tissue involution associated with progressive restriction in progenitor competence.
Zan Huang, Zengdi Zhang, Zahra Moazzami, Ryan Heck, Ping Hu, Hai-Bin Ruan

Cell Rep· April 2022

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Glucosamine facilitates cardiac ischemic recovery via recruiting Ly6C monocytes in a STAT1 and O-GlcNAcylation-dependent fashion.
Wenjing Zhou, Xuan Jiang, Qingsong Tang, Liang Ding, Weizhang Xiao, Hai-Bin Ruan

Clin Transl Med· March 2022

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Editorial: Crosstalk Between the Metabolic and Cardiovascular Systems in the Brain.
Jin Kwon Jeong, Hai-Bin Ruan, Chitoku Toda

Front Physiol· January 2022

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Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice.
Ramkumar Mohan, Seokwon Jo, Elina Da Sol Chung, Eunice Oribamise, Amber Lockridge, Hai-Bin Ruan

Cells· October 2021

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Developmental and functional heterogeneity of thermogenic adipose tissue.
Hai-Bin Ruan

J Mol Cell Biol· October 2020

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Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells.
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Meng Cheng, Zengdi Zhang, Hai-Bin Ruan

Cell Rep· August 2020

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O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth.
Jay Prakash Singh, Kevin Qian, Jeong-Sang Lee, Jinfeng Zhou, Xuemei Han, Hai-Bin Ruan

Oncogene· January 2020

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The glycoprotein follistatin-like 1 promotes brown adipose thermogenesis.
Dongliang Fang, Xinyi Shi, Tao Lu, Haibin Ruan, Yan Gao

Metabolism· September 2019

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Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control colitis.
Ruixue Liu, Richard Moriggl, Dongsheng Zhang, Haifeng Li, Rebekah Karns, Hai-Bin Ruan

Life Sci Alliance· April 2019

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