Publications by authors named "Hal A Lewis"

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Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors.
Guanglin Luo, Ling Chen, Swanee Jacutin-Porte, Ying Han, Catherine R Burton, Hal A Lewis

Bioorg Med Chem Lett· February 2023

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Neutrophil-predominant bullous pemphigoid induced by checkpoint inhibitors: A case series.
Lisa M Morris, Hal A Lewis, Lynn A Cornelius, David Y Chen, Ilana S Rosman

J Cutan Pathol· August 2020

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Pemphigus foliaceus in a patient with gastrointestinal stromal tumor treated with adjuvant imatinib mesylate.
Hal A Lewis, David Y Chen, Ilana S Rosman, Joel Picus, Milan J Anadkat

Dermatol Online J· June 2020

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5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors.
Kevin M Peese, Christopher W Allard, Timothy Connolly, Barry L Johnson, Chen Li, Hal A Lewis

J Med Chem· February 2019

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Overuse of Magnetic Resonance Imaging in the Diagnosis and Treatment of Moderate to Severe Osteoarthritis.
Seth L Sherman, Trevor R Gulbrandsen, Hal A Lewis, Martin H Gregory, Nicholas M Capito

Iowa Orthop J· December 2018

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Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form.
Micah T Nelp, Patrick A Kates, John T Hunt, John A Newitt, Aaron Balog, Hal A Lewis

Proc Natl Acad Sci U S A· March 2018

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Methotrexate-induced cutaneous ulceration in 3 nonpsoriatic patients: Report of a rare side effect.
Hal A Lewis, Kathleen M Nemer, Rebecca J Chibnall, Amy C Musiek

JAAD Case Rep· May 2017

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Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors.
Guanglin Luo, Ling Chen, Catherine R Burton, Hong Xiao, Prasanna Sivaprakasam, Hal A Lewis

J Med Chem· February 2016

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Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.
Annette Ehrhardt, W Joon Chung, Louise C Pyle, Wei Wang, Krzysztof Nowotarski, Hal A Lewis

J Biol Chem· January 2016

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Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core.
Prasanna Sivaprakasam, Xiaojun Han, Rita L Civiello, Swanee Jacutin-Porte, Kevin Kish, Hal A Lewis

Bioorg Med Chem Lett· May 2015

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Human apolipoprotein E4 worsens acute axonal pathology but not amyloid-β immunoreactivity after traumatic brain injury in 3xTG-AD mice.
Rachel E Bennett, Thomas J Esparza, Hal A Lewis, Eddie Kim, Christine L Mac Donald

J Neuropathol Exp Neurol· May 2013

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Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.
Samuel W Gerritz, Christopher Cianci, Sean Kim, Bradley C Pearce, Carol Deminie, Hal A Lewis

Proc Natl Acad Sci U S A· September 2011

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Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Shane Atwell, Christie G Brouillette, Kris Conners, Spencer Emtage, Tarun Gheyi, Hal A Lewis

Protein Eng Des Sel· May 2010

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SGX393 inhibits the CML mutant Bcr-AblT315I and preempts in vitro resistance when combined with nilotinib or dasatinib.
Thomas O'Hare, Christopher A Eide, Jeffrey W Tyner, Amie S Corbin, Matthew J Wong, Hal A Lewis

Proc Natl Acad Sci U S A· April 2008

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Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure.
Hal A Lewis, Xun Zhao, Chi Wang, J Michael Sauder, Isabelle Rooney

J Biol Chem· January 2005

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Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Hal A Lewis, Sean G Buchanan, Stephen K Burley, Kris Conners, Mark Dickey

EMBO J· January 2004

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