Publications by authors named "Halide Edip Temel"

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Cyclooxygenase Inhibitor 4-Methylthiazole Derivative Compound Alleviates Lipopolysaccharides-Induced Neuroinflammation in Male Rats With Regulating Cytokine Levels.
Ezgi Kar, Özkan Alataş, Fatih Kar, Leyla Yurttaş, Asaf Evrim Evren, Halide Edip Temel

J Biochem Mol Toxicol· December 2025

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Synthesis, molecular docking, and molecular dynamic simulation studies of new 1,3,4-thiadiazole derivatives as potential apoptosis inducers in A549 lung cancer cell line.
Leyla Yurttaş, Asaf Evrim Evren, Huda AlChaib, Halide Edip Temel, Gülşen Akalin Çiftçi

J Biomol Struct Dyn· May 2025

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Development and Biological Assessment of Thiazole-Based Pyridines for Targeted Therapy in Lung Cancer.
Demokrat Nuha, Sam Dawbaa, Asaf Evrim Evren, Zennure Şevval Çi Yanci, Halide Edip Temel

ACS Omega· May 2025

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Design, synthesis of novel thiazole-thiomorpholine derivatives and evaluation of their anticancer activity via in vitro and in silico studies.
Sam Dawbaa, Asaf Evrim Evren, Demokrat Nuha, Halide Edip Temel, Gülşen Akalin Çiftçi

Arch Pharm (Weinheim)· March 2025

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Chemical profile, pharmacological activity and Ten. evaluation of essential oil based on distillation time.
Gülsüm Yıldız, Selen İlgün, Gökçe Şeker Karatoprak, Yavuz Bülent Köse, Fatih Göger, Halide Edip Temel

Int J Environ Health Res· April 2024

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Synthesis of Some New 1,3,4-Oxadiazole Derivatives and Evaluation of Their Anticancer Activity.
Leyla Yurttaş, Asaf Evrim Evren, Aslıhan Kubilay, Mehmet Onur Aksoy, Halide Edip Temel

ACS Omega· December 2023

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Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action.
Mehlika Dilek Altıntop, Gülşen Akalın Çiftçi, Nalan Yılmaz Savaş, İpek Ertorun, Betül Can, Halide Edip Temel

Int J Mol Sci· January 2023

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Design, synthesis and biological evaluation of a new series of arylidene indanones as small molecules for targeted therapy of non-small cell lung carcinoma and prostate cancer.
Mehlika Dilek Altıntop, Ahmet Özdemir, Halide Edip Temel, Bahar Demir Cevizlidere, Belgin Sever

Eur J Med Chem· December 2022

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New chromanone derivatives containing thiazoles: Synthesis and antitumor activity evaluation on A549 lung cancer cell line.
Leyla Yurttaş, Halide Edip Temel, Mehmet Onur Aksoy, Emre Fatih Bülbül, Gülşen Akalin Çiftçi

Drug Dev Res· April 2022

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Biological Activity Evaluation of Novel 1,2,4-Triazine Derivatives Containing Thiazole/Benzothiazole Rings.
Leyla Yurttas, Gulsen Akalin Ciftci, Halide Edip Temel, Begum Nurpelin Saglik, Bahar Demir

Anticancer Agents Med Chem· June 2019

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Synthesis and Evaluation of a New Series of Thiazolyl-pyrazoline Derivatives as Cholinesterase Inhibitors.
Halide Edip Temel, Mehlika Dilek Altintop, Ahmet Özdemir

Turk J Pharm Sci· December 2018

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New Thiazoline-Tetralin Derivatives and Biological Activity Evaluation.
Gülhan Turan-Zitouni, Leyla Yurttaş, Aouatef Tabbi, Gülşen Akalın Çiftçi, Halide Edip Temel

Molecules· January 2018

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Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors.
Zafer Asim Kaplancikli, Mehlika Dilek Altıntop, Ozlem Atli, Belgin Sever, Merve Baysal, Halide Edip Temel

Anticancer Agents Med Chem· September 2017

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Synthesis and Evaluation of New Oxadiazole, Thiadiazole, and Triazole Derivatives as Potential Anticancer Agents Targeting MMP-9.
Ahmet Özdemir, Belgin Sever, Mehlika Dilek Altıntop, Halide Edip Temel, Özlem Atlı

Molecules· July 2017

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Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities.
Betul Demirci, Hasan Soliman Yusufoglu, Nurhayat Tabanca, Halide Edip Temel, Ulrich R Bernier

Saudi Pharm J· July 2017

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Synthesis and Evaluation of New Benzodioxole- Based Thiosemicarbazone Derivatives as Potential Antitumor Agents.
Mehlika Dilek Altıntop, Halide Edip Temel, Belgin Sever, Gülşen Akalın Çiftçi, Zafer Asım Kaplancıklı

Molecules· November 2016

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NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na(+)/K(+) ATPase activity and lipid profile.
Neslihan Tekin, Fahrettin Akyüz, Halide Edip Temel

Diabetes Metab Syndr· July 2016

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The impact of klotho gene polymorphisms on urinary tract stone disease.
Abdullah Gürel, İyimser Üre, Halide Edip Temel, Oğuz Çilingir, Sema Uslu

World J Urol· July 2016

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Supplemental carvacrol can reduce the severity of inflammation by influencing the production of mediators of inflammation.
Mehmet Kara, Sema Uslu, Fatih Demirci, Halide Edip Temel, Canan Baydemir

Inflammation· February 2016

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Synthesis and evaluation of bis-thiazole derivatives as new anticancer agents.
Gülhan Turan-Zitouni, Mehlika Dilek Altıntop, Ahmet Özdemir, Zafer Asım Kaplancıklı, Gülşen Akalın Çiftçi, Halide Edip Temel

Eur J Med Chem· January 2016

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Butrylcholinesterase activity in chronic liver disease patients and correlation with Child-Pugh classification and MELD scoring system.
Halide Edip Temel, Tuncer Temel, Dondu Uskudar Cansu, Ayşegul Ozakyol

Clin Lab· June 2015

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Serum thrombopoietin levels and its relationship with thrombocytopenia in patients with cirrhosis.
Tuncer Temel, Dondu Uskudar Cansu, Halide Edip Temel, Aysegul Harmanc Ozakyol

Hepat Mon· May 2014

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Synthesis and biological evaluation of some thiazole derivatives as new cholinesterase inhibitors.
Gülhan Turan-Zitouni, Ahmet Ozdemir, Zafer Asim Kaplancikli, Mehlika Dilek Altintop, Halide Edip Temel

J Enzyme Inhib Med Chem· June 2013

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Effects of lipoprotein-associated phospholipase A2 on arginase/nitric oxide pathway in hemodialysis patients.
Ayşegül Korkmaz Tektaş, Sema Uslu, Ahmet Uğur Yalçin, Garip Sahin, Gökhan Temiz, Halide Edip Temel

Ren Fail· October 2012

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Synthesis and anticholinesterase activity and cytotoxicity of novel amide derivatives.
Mehlika Dilek Altintop, Zafer Asim Kaplancikli, Ahmet Ozdemir, Gülhan Turan-Zitouni, Halide Edip Temel

Arch Pharm (Weinheim)· February 2012

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