Publications by authors named "Hamish Allen"

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Effect-based monitoring of two rivers under urban and agricultural influence reveals a range of biological activities in sediment and water extracts.
Frederic D L Leusch, Hamish Allen, Nuwan A L De Silva, Roger Hodson, Matthew Johnson

J Environ Manage· February 2024

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Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1).
Paul Galatsis, Bradley Caprathe, John Gilmore, Anthony Thomas, Kristin Linn, Hamish Allen

Bioorg Med Chem Lett· September 2010

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Inhibition of interleukin-1beta converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones.
Paul Galatsis, Bradley Caprathe, Dennis Downing, John Gilmore, William Harter, Hamish Allen

Bioorg Med Chem Lett· September 2010

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Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-alpha production.
Kevin Cusack, Hamish Allen, Agnieszka Bischoff, Anca Clabbers, Richard Dixon

Bioorg Med Chem Lett· March 2009

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Discovery of thieno[2,3-c]pyridines as potent COT inhibitors.
Dawn George, Michael Friedman, Hamish Allen, Maria Argiriadi, Claude Barberis

Bioorg Med Chem Lett· September 2008

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Comparative analysis of various in vitro COT kinase assay formats and their applications in inhibitor identification and characterization.
Yong Jia, Christopher M Quinn, Anca Clabbers, Robert Talanian, Yajun Xu, Hamish Allen

Anal Biochem· March 2006

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Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kappa B1 p105.
Yong Jia, Christopher M Quinn, Nancy J Bump, Kevin M Clark, Anca Clabbers, Hamish Allen

Arch Biochem Biophys· September 2005

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Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction.
Stefan Frantz, Anique Ducharme, Douglas Sawyer, Luis E Rohde, Lester Kobzik, Hamish Allen

J Mol Cell Cardiol· June 2003

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betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.
Valerie Lang, Julia Janzen, Gregory Zvi Fischer, Yasmina Soneji, Sören Beinke, Hamish Allen

Mol Cell Biol· January 2003

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Structure-based design of nonpeptide inhibitors of interleukin-1beta converting enzyme (ICE, caspase-1).
Aurash B Shahripour, Mark S Plummer, Elizabeth A Lunney, Hans P Albrecht, Sheryl J Hays, Hamish J Allen

Bioorg Med Chem· January 2002

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