Publications by authors named "Han Witjes"

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Exposure-Response Analysis of Donidalorsen for the Treatment of Hereditary Angioedema.
Pratap Singh, Han Witjes, Huub Jan Kleijn, John K Diep, Laura Bordone

Clin Transl Sci· November 2025

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Characterizing the exposure-response relationship of idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma.
Jamie N Connarn, Han Witjes, Marielle van Zutphen-van Geffen, Rik de Greef, Timothy B Campbell

CPT Pharmacometrics Syst Pharmacol· November 2023

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Mobocertinib Dose Rationale in Patients with Metastatic NSCLC with EGFR Exon 20 Insertions: Exposure-Response Analyses of a Pivotal Phase I/II Study.
Neeraj Gupta, Anna Largajolli, Han Witjes, Paul M Diderichsen, Steven Zhang

Clin Pharmacol Ther· August 2022

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Magnesium sulfate pharmacokinetics after intramuscular dosing in women with preeclampsia.
Kathleen Brookfield, Hadiza Galadanci, Lihong Du, Larissa Wenning, Idris Mohammed, Han Witjes

AJOG Glob Rep· November 2021

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Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis.
Brian M Maas, Jos Lommerse, Nele Plock, Radha A Railkar, S Y Amy Cheung, Han Witjes

EBioMedicine· November 2021

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Meta-Analyses of Clinical Efficacy of Risankizumab and Adalimumab in Chronic Plaque Psoriasis: Supporting Evidence of Risankizumab Superiority.
Han Witjes, Amit Khatri, Paul M Diderichsen, Jaap Mandema, Ahmed A Othman

Clin Pharmacol Ther· February 2020

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Alternative Magnesium Sulfate Dosing Regimens for Women With Preeclampsia: A Population Pharmacokinetic Exposure-Response Modeling and Simulation Study.
Lihong Du, Larissa A Wenning, Brendan Carvalho, Lelia Duley, Kathleen F Brookfield, Han Witjes

J Clin Pharmacol· November 2019

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Maternal-Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing.
Jos Lommerse, Diana Clarke, Thomas Kerbusch, Henri Merdjan, Han Witjes

CPT Pharmacometrics Syst Pharmacol· September 2019

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Operating characteristics of stepwise covariate selection in pharmacometric modeling.
Malidi Ahamadi, Anna Largajolli, Paul M Diderichsen, Rik de Greef, Thomas Kerbusch, Han Witjes

J Pharmacokinet Pharmacodyn· June 2019

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Population Pharmacokinetic Modeling to Evaluate Standard Magnesium Sulfate Treatments and Alternative Dosing Regimens for Women With Preeclampsia.
Lihong Du, Larissa Wenning, Elizabeth Migoya, Yan Xu, Brendan Carvalho, Han Witjes

J Clin Pharmacol· March 2019

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Population pharmacokinetics and exposure-response of osimertinib in patients with non-small cell lung cancer.
Kathryn Brown, Craig Comisar, Han Witjes, John Maringwa, Rik de Greef

Br J Clin Pharmacol· June 2017

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Comparative analysis of the effects of nomegestrol acetate/17 β-estradiol and drospirenone/ethinylestradiol on premenstrual and menstrual symptoms and dysmenorrhea.
Han Witjes, Mitchell D Creinin, Inger Sundström-Poromaa, Allison Martin Nguyen, Tjeerd Korver

Eur J Contracept Reprod Health Care· March 2016

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Large, comparative, randomized double-blind trial confirming noninferiority of pregnancy rates for corifollitropin alfa compared with recombinant follicle-stimulating hormone in a gonadotropin-releasing hormone antagonist controlled ovarian stimulation protocol in older patients undergoing in vitro fertilization.
Robert Boostanfar, Bruce Shapiro, Michael Levy, Zev Rosenwaks, Han Witjes

Fertil Steril· July 2015

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Prognostic models for high and low ovarian responses in controlled ovarian stimulation using a GnRH antagonist protocol.
Frank J Broekmans, Pierre J M Verweij, Marinus J C Eijkemans, Bernadette M J L Mannaerts, Han Witjes

Hum Reprod· August 2014

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Short follicular phase of stimulation following corifollitropin alfa or daily recombinant FSH treatment does not compromise clinical outcome: a retrospective analysis of the Engage trial.
Tonko Mardešič, Bernadette Mannaerts, Mostafa Abuzeid, Michael Levy, Han Witjes

Reprod Biomed Online· April 2014

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Reply of the authors.
Georg Griesinger, Bernadette Mannaerts, Claus Yding Andersen, Han Witjes, Efstratios M Kolibianakis

Fertil Steril· January 2014

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Progesterone elevation does not compromise pregnancy rates in high responders: a pooled analysis of in vitro fertilization patients treated with recombinant follicle-stimulating hormone/gonadotropin-releasing hormone antagonist in six trials.
Georg Griesinger, Bernadette Mannaerts, Claus Yding Andersen, Han Witjes, Efstratios M Kolibianakis

Fertil Steril· December 2013

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Clinical impact of LH rises prior to and during ganirelix treatment started on day 5 or on day 6 of ovarian stimulation.
John L Frattarelli, Torbjörn Hillensjö, Frank J Broekmans, Han Witjes, Jolanda Elbers

Reprod Biol Endocrinol· September 2013

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Corifollitropin alfa or rFSH treatment flexibility options for controlled ovarian stimulation: a post hoc analysis of the Engage trial.
Arthur Leader, Paul Devroey, Han Witjes, Keith Gordon

Reprod Biol Endocrinol· June 2013

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High ovarian response does not jeopardize ongoing pregnancy rates and increases cumulative pregnancy rates in a GnRH-antagonist protocol.
Human M Fatemi, Kevin Doody, Georg Griesinger, Han Witjes, Bernadette Mannaerts

Hum Reprod· February 2013

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A randomized controlled trial of the GnRH antagonist ganirelix in Chinese normal responders: high efficacy and pregnancy rates.
Jie Qiao, Guangxiu Lu, H W Zhang, Hua Chen, Caihong Ma, Han Witjes

Gynecol Endocrinol· October 2012

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A comparison of live birth rates and cumulative ongoing pregnancy rates between Europe and North America after ovarian stimulation with corifollitropin alfa or recombinant follicle-stimulating hormone.
Robert Boostanfar, Bernadette Mannaerts, Samuel Pang, Manuel Fernandez-Sanchez, Han Witjes

Fertil Steril· June 2012

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No association between endogenous LH and pregnancy in a GnRH antagonist protocol: part II, recombinant FSH.
George Griesinger, Daniel B Shapiro, Efstratios M Kolibianakis, Han Witjes, Bernadette M Mannaerts

Reprod Biomed Online· October 2011

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No association between endogenous LH and pregnancy in a GnRH antagonist protocol: part I, corifollitropin alfa.
Kevin J Doody, Paul Devroey, Arthur Leader, Han Witjes, Bernadette M Mannaerts

Reprod Biomed Online· October 2011

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Corifollitropin alfa in a long GnRH agonist protocol: proof of concept trial.
Human M Fatemi, Janine Oberyé, Biljana Popovic-Todorovic, Han Witjes, Bernadette Mannaerts

Fertil Steril· October 2010

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